Auto-Antibodies Flashcards
1
Q
Anti-CCP
A
Rheumatoid Arthritis
2
Q
ANA -Anti-nuclear antibody
A
SLE, Sjogren’s syndrome, systemic sclerosis, MCTD, autoimmune liver disease
3
Q
anti-double stranded DNA antibody - dsDNA
A
SLE
4
Q
Anti-Sm
A
SLE
5
Q
Anti-Ro
A
SLE, Sjogren’s syndrome
6
Q
Anti-La
A
Sjogren’s syndrome
7
Q
Anti-centromere antibody
A
Systemic sclerosis (limited)
8
Q
Anti-Scl-70 antibody
A
Systemic sclerosis (diffuse)
9
Q
Anti-RNP antibody
A
SLE, MCTD
10
Q
Anti-Jo-1 antibody
A
myositis
11
Q
Anti-cardiolipin antibody and lupus anti-coagulant
A
Anti-phospholipid syndrome
12
Q
ANCA
A
Small vessel vasculitis (GPA, EPGA, MPA)
13
Q
Rheumatoid arthritis
A
Anti-CCP (cyclic citrullinated peptide) - 70% sensitive, and 97% specific
Rheumatoid Factor - 70% and 90%
Inflammatory markers - PV, CRP, ESR
