Auto-Antibodies Flashcards

1
Q

anti-dsDNA

A

50-75% specific for SLE

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2
Q

anti-Ro

A

95% specific for SLE, Sjogren’s

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3
Q

anti-SM

A

30% specific for SLE

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4
Q

anti-U1RNP (spliceosome)

A

mixed connective tissue disease

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5
Q

anti-histone

A

90% specific for drug lupus (ex: hydralazine)

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6
Q

rheumatoid factor

A

IgM against Fc of IgG; 85% specific for rheumatoid arthritis

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7
Q

anti-citrullinated protein antibody (APCA)

A

Agn –PADI–> Citrulline (neutral); HIGHLY specific for rheumatoid arthritis

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