Autism Flashcards

1
Q

What is the triad of autism?

A
  1. Social interaction
  2. Social communication
  3. Social Imagination
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2
Q

How is social interaction seen in autism?

A
  • Difficulty recognising emotions, in themselves and others
  • Unwilling to make direct eye contact
  • Unaware of appropriate social behaviour - failure to share toys or take turns in conversation, indifferent or adverse to physical affection
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3
Q

How is social communication seen in autism?

A
  • Some children are late to start talking or remain nonverbal - if speaking, often monotone and lack of gestures
  • May not respond to own name
  • Difficulty understanding non-verbal communication and they themselves may have absent facial expressions
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4
Q

How is social imagination seen in autism?

A
  • Children often have a limited range of interests
  • They may favour one toy greatly or can’t talk about another topic apart from their interest
  • Patterns of play can be repetitive
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5
Q

What is autism linked to?

A
  • Anxiety and poor stress management
  • May have problems with loud noises, textures, water etc, consider seeking or avoiding behaviours
  • Low mood and depression (may worsen in adolescence)
  • OCD
  • Sleep disturbance
  • Gender dysmorphia
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6
Q

What is the management for autism?

A
  • No cure, just learning how to manage behaviour, become independent e.g. specialist teaching schools
  • Educate family on how to manage
  • 40% of autism patients having a learning disability
  • Getting help - health visitor and specialist health visitor, parent groups and voluntary organisations, specialist teaching and schools (to help develop social skills)
  • Education Health and Care Plan, Disability Living Allowance
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7
Q

What is the psychotherapy for autistic patients and their parents?

A
  • CBT
  • Behaviour management programmes
  • Applied Behavioural Analysis program - intense 40hrs/wk for 3yrs based on operant conditioning, imitation and reinforcement
  • TEACCH - treatment and education for autistic and related communication handicapped children programme - successful in reducing self-injurious behaviour and enhancing life skills
  • Educational psychology
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8
Q

What medications can be used as an adjunct to psychological interventions in autism?

A
  • SSRIs - main treatment for repetitive behaviours, anxiety, aggression. Require lower doses than needed for antidepressant effects.
  • 2nd gen antipsychotics - 1st line pharmacological treatment for aggression, self-injury etc is risperidone
  • Melatonin - help reduce sleep latency
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9
Q

What are risk factors for autism?

A
  • Male 4:1
  • Congenital rubella infections - exposure in 1st trimester in early brain development
  • Strong link between learning disabilities and seizure disorders
  • 90% heritability rate and recurrence rate of 2-8% among siblings
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10
Q

What social and emotional interaction questions do you want to ask in the history?

A
  • Can they make and keep friends
  • Do they understand emotions (their own and others)
  • Do they like making eye contact? Abnormal body postures? e.g. walking on tiptoes
  • Not clear of social cues (age appropriate
  • Special narrowed interests e.g. trains, jigsaw, TV stars, star wars etc, cannot talk details about other topic apart from their interest
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11
Q

What flexibility of thought questions do you want to ask in the history?

A
  • Imaginative or repetitive play
  • Mannerisms (tip toe walking/hand flapping)
  • How they cope with change?
  • Any obsessions? Routines? Rituals?
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12
Q

What language and communication questions do you want to ask in the history?

A
  • Can they have a two way conversation?
  • Pitch, tone and content of speech
  • Gestures while communicating
  • Echolalia (understanding < expression)
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13
Q

What questions do you ask about sensory features, sleep and diet?

A
  • Any problems with loud noises, textures, water - consider sensory seeking or avoiding behaviours
  • Consider co-morbidites: ADHD, developmental coordination disorder (dyspraxia), intellectual disability, tics, specific learning difficulties such as dyslexia, dyscalculia
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14
Q

What questions do you want to ask in the history about behaviour and development?

A
  • Temper problems? Meltdowns?
  • Obsessions, fears and phobias
  • How do they cope with being left alone/waiting?
  • Gross motor or fine motor movement
  • Hearing, speech and language - progression of speech, regression is a RED FLAG
  • Social interaction and play development
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15
Q

What do you want to know about the birth history?

A
  • Antenatal hx of alcohol, drugs, smoking or illness
  • Perinatal - delivery problems or LBW
  • Postnatal problems e.g. infections, epilepsy, delays
  • Congenital rubella and phenylketonuria are associated with autism
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16
Q

What do you want to know about the family hx?

A
  • Consanguinity
  • Developmental and learning problems
  • Epilepsy and fits
  • Alcohol and drug abuse, domestic violence or parents are care leavers
  • Consider attachment difficulties which can be confused with ASD
17
Q

What specific questions do you want to ask the parents?

A
  • What are the parent/teacher/caregiver’s main concerns?
  • Ask about all behaviours at home, school, day centre etc
  • Ask about family circumstances; how is everything at home? Any other siblings, are they like this?
18
Q

How would you assess suspected autism?

A
  • Interactive assessment/observation of communication skills and behaviours
  • Schedule of growing skills or Oriffith Mental Developmental Scales
  • ADOS2 (Autism Diagnostic Observation Schedule) - uses play and interview to examine communication, social interaction, imagination and restricted/repetitive behaviours
  • DISCO (Diagnostic Interview for Social and Communication Disorders)
  • ADI-R (Autism Diagnostic Interview-Revised)
19
Q

Describe ADOS2

A
  • Toddler module: 12-30mths, don’t consistently use phrase speech
  • Module 1: >/=31mths, don’t consistently use phrase speech
  • Module 2: children of any age who use phrase speech but not verbally fluent
  • Module 3: verbally fluent children + young adolescants
  • Module 4: verbally fluent older adolescants and adults
  • Score put in algorithm to give autism, autism spectrum, non-spectrum
20
Q

Describe the DISCO assessment tool

A

Interview with parent/carer of patient to gain holistic understanding of patient’s character/lifestyle.

21
Q

Describe the ADI-R assessment tool

A

Made up of 93 items: focuses on 3 functional domains: language + communication; reciprocal social interactions, restricted, repetitive and stereotyped behaviours and interests

22
Q

What physical exam would you want to do for autism?

A
  • General physical exam
  • Height, weight + head circumference
  • Gait + coordination (look at heel/toe)
  • Throwing/catching
  • Fogs test (tests movement to assess for neurological issues)
  • Skin stigmata and neurocutaneous markers
  • Injuries (self-harm or maltreatment)
  • Congenital anomalies or dysmorphic features - consider genetic testing
  • MSE (secondary MH conditions)
23
Q

How is a diagnosis of autism made?

A
  • Never diagnosed on 1st clinical appointment
  • Psychiatrist/psychologist/SALT/paediatrician assessments
  • Involve school
  • Cambridge questionnaire, CAST questionnaire
  • Map to DSM-V criteria/ICD-10
24
Q

What is a needs based management plan for autism?

A
  • Take the family and educational context into account
  • Communicate findings to parents and child if appropriate
  • Provide a written report explaining findings and reasons for conclusions, copy report to GP, parents, school
25
Q

What health professionals can help manage autism?

A
  • Health visitor and specialist health visitor
  • Parent groups and voluntary organisations
  • National Autistic Society of action for ASD
  • Portage (pre-school home visiting special educational needs support service)
  • ECHP (Education Health and Care Plan), DLA (Disability Living Allowance)
  • S+L therapists
26
Q

What factors are indicative of a good prognosis?

A
  • Communicative speech 6yrs old and above
  • Higher IQ (>50)
  • Skills that can be used to secure employment
27
Q

How is aggression managed in children?

A
  • Psychological interventions are tried and a physical cause for aggressive behaviour is ruled out or treated first.
  • Risperidone is the only licensed pharmacological treatment.