Autacoids Flashcards

1
Q

Name the uricosuric drugs.

A
  1. Probenecid
  2. Sulfinpyrazone
  3. Losartan
  4. Fenofibrate
  5. Lesinurad
  6. Benzbromarone (effective in renal failure)
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2
Q

Drugs used in acute gout.

A
  1. NSAIDS— Indimethacin (DOC), Naproxen, Piroxicam, Diclofenac, Etoricoxib
  2. Colchicine ( Inhibits release of chemotavtic factors and migration of leukocytes to the inflammed joints)
  3. Corticosteroids- If only 1-2 joints are involved, intraarticular Triamcenolone can be given. Systemic steroids (Prednisone) given only when patient cannot tolerate NSAIDs/Colchicine or they are contraindicated (renal failure or peptic ulcer)
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3
Q

Treatment of Status asthmaticus.

A
  1. 100 mg i.v. Hydrocortisone given immediately.
    Followed by 100-200 mg i.v. infusion over 4-8 hours.
  2. Nebulized Salbutamol (5mg) + Ipratropium bromide (0.5mg) - inhalational route
  3. High flow oxygen inhalational
  4. Salbutamol/Terbutaline i.m. or s.c. because inhalational drug may not reach peripheral bronchi adequately due to plugging of airways by mucus.
  5. Intubation+ mechanical ventilation
  6. Treat chest infection with intensive antibiotic therapy
  7. Correct acidosis by Sod bicarbonate

7.

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