Audiology Lesson 5 - Middle Ear Disorders Flashcards

1
Q

Describe Otitis Media and list its various manifestations

A

Otitis media is a middle ear inflammation.

  • Otitis media with effusion,
  • Acute suppurative otitis media,
  • Barotrauma of the middle ear,
  • Chronic suppurative otitis media,
  • Chronic otitis
    media with cholesteatoma.

All of these disorders are related to a dysfunction of the Eustachian tube

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2
Q

Describe how middle ear disorders are related to Eustachian Tube Dysfunction

A

Eustachian tube dysfunction leads to a middle ear disventilation, so a negative pressure that leads to edema and flogosis of the middle ear.

Note: These infections are more common in pediatric patients because the eustachian tube in infants and children is different from that of adults - it is shorter
in pediatric age and it runs more horizontally; in this way infections derived from the nasopharynx are more frequent

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3
Q

Describe the main causes of Eustachian tube obstruction

A

Extrinsic pressure

i. adenoids (usually a bilateral problem)
ii. tumors of the rhinopharynx or cysts in adults
iii. nasal packing
iv. nasogastric feeding tube.

Edema: 
i.	Rhinosinusitis
ii.	Allergies
iii.	Wegener granulomatosis 
	a very important vasculitis that involves the upper airways and sometimes also the ear
iv.	radiotherapy 

c. Malfunction of tubal muscles: (The levator and tensor palatini)
i. Down syndrome
ii. cleft palate.

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4
Q

When should you suspect a tumour in a case of otitis media?

A

If there is an inflammation of the upper airways, usually the problem is BILATERAL ;

if there is adenoids (which are typical in
children) also the problem is BILATERAL.

A MONOLATERAL problem in adults without history of inflammation should lead you to suspect a tumor, which is a unilateral condition. In these
patients you must perform a fibroscopy to evaluate the nasopharynx and to exclude a tumor.

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5
Q

Describe Otitis Media with Effusions and elaborate on the types of effusions

A

This is otitis media which is characterized by the presence of effusive fluids, which means non suppurative fluids in the middle ear.

Very frequent in pre-school age; it generally affects both ears and it is typical of the winter season.

Symptoms:
▪ Hearing loss & fullness
▪ Mild ear pain.

TYPES OF EFFUSIONS

Serous effusion can be observed, through the tympanic membrane with air bubbles in the middle ear

Mucous effusion has a bulging of the tympanic membrane due to the presence of mucous in the middle ear.

Glue Ear where the mucous in the middle ear resembles glue. It is characterized by a metaplasia of the epithelium of the middle ear, in particular there is a change from cuboidal to columnar mucous producing epithelium and the result is a chronic conductive hearing loss.

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6
Q

Describe the management of Glue Ear

A

In this situation we need to resolve the conductive
hearing loss, which may be at about 60 dB, significant!

In this situation we must perform an incision in the tympanic membrane and remove the glue by means of aspiration

However, we need
to be sure that our clinical diagnosis is chronic otitis
media because it can sometimes be misdiagnosed with the other types of blue tympanum.

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7
Q

Explain what blue tympanum is and describe all it’s causes

A

Blue tympanum is an otomacroscopic finding characterized by a typical blue color of the tympanum.

CAUSES
- Blood collection after a barotraumatic event

  • An abnormal jugular bulb
  • Acute Otitis media with effusion
  • A glomus tumour (in this case making an incision in the tympanic membrane would be a big mistake!)
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8
Q

Describe the Tympanometry curves we may observe in otitis media

A

Type C - mild involvement of the conductive system

Type B - Complete conductive system involvement - severe conductive hearing loss

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9
Q

Fully describe suppurative otitis media, its diagnosis and clinical picture, natural history and compliactions

A

It is a suppurative infection with BACTERIAL etiology

The most common bacterial agents are:
▪ S. Pneumoniae (25-30%),
▪ H. Influenza (40-45%),
▪ M. Catarrhalis (10-15%).

It is a disorder typical of winter season

Typical symptoms are:

  • Severe ear pain,
  • Hearing loss,
  • Fever
  • Purulent aural discharge only if there is a perforation.

Diagnosis is otoscopic, there are distinguishable 3 phases in the natural history:

  1. Hyperemic and exudative phase -
    characterized by hyperemic tympanic membrane
  2. Rupture phase -
    Perforation of the tympanic membrane. There is aural discharge, and usually a resolution of ear pain (as earpain is usually caused by the bulging of the tympanic membrane)

c. Healing phase

When complications are suspected, imaging tests are required

COMPLICATIONS OF SUPPERATIVE OTITIS MEDIA

  • Sensorineural hearing loss: CT scan should be performed
  • Vertigo/dizziness: because vertigo is the expression of the involvement of the vestibular system of the inner ear.
  • Headache (may signify edema)

The treatment is systemic antibiotics

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10
Q

Describe Chronic suppurative otitis media and its symptoms

A

Chronic suppurative otitis media is characterized by a persistent perforation of the tympanic membrane and by suppurative involvement of the tympanic cavity.

The suppurative involvement comes from watery income of microorganism or an upper airways infection.

Eustachian tube dysfunction and nature, pathogenicity, resistance of infecting organisms (S. Aureus,Proteus,
Pseudomonas) are involved in chronic suppurative otitis media

SYMPTOMS

  • Aural discharge with fetid smell (due to presence of anaerobes)
  • Hearing loss (conductive or mixed, as infection may reach the inner ear via the round window)
  • Ear pain (rarely)

Chronic suppurative otitis media is a typical tympanoplasty candidate

Chronic suppurative otitis media may be wet or dry

  • dry (only chronic perforation)
  • wet (there is also a suppurative event)
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11
Q

Explain how to differentiate between the left ear and the right ear on otomicroscope

A

By looking at the manubrium of the malleus.

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12
Q

Fully describe what a cholesteatoma is and it’s histopathology and classification

A

“wrong skin in the wrong place” when put simply

From an histo-pathological point of view it is made up of three layers:

  1. A central mass characterized by an accumulation of keratin.
  2. A matrix which is a stratified squamous epithelium. It is very important to remove matrix during surgical removal of the cholesteatoma. If we do not completely remove the matrix there will be recurrence of the disease. Moreover the matrix determines the progressive uncontrolled growth of the cholesteatoma.
  3. The last layer is the peri-matrix, it is an inflammatory reactive tissue.
CLASSIFICATION
From a topographic point of view we classify it into:
1. choleastoma of the external ear
2. choleastoma of the middle ear
3.petrous bone cholesteatoma
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13
Q

Discuss the pathophysiology of cholesteatoma (congenital and aquired) - ALL THEORIES

A

There are 5 theories for the pathophysiology of cholesteatoma.

  1. Congenital theory - embryonic inclusions or rests of epithelial cells - probably epidermal rests in the amniotic fluid collecting in the tympanic cavity through the Eustachian tube and consequently cholesteatoma develops in the antero-superior quadrant of the tympanic cavity . This is related to the congenital form.
  2. Metaplasia theory - acquired cholesteatoma which is the result of recurrent otitis.
  3. Migration or invasion theory: the cholesteatoma is result of migration of squamous epithelial cell along the tympanic membrane perforation. Usually it happens when the perforation involves the annulus because annulus represents a protection between the middle ear and the external one.
  4. Basal cell hyperplasia or papillary ingrowth theory - cholesteatoma arisinf from an intact pars flaccida
  5. MOST IMPORTANT - the Invagination theory. A Dynfunctional eustachian tube results in –> impaired ventilation in the middle ear –>This results in a structural weakening of the TM –> retraction pockets can form (which aren’t self cleaning) –> lead to the accumulation of keratin debris which is the first step in the formation of a cholesteatoma. If it develops there will be a perforation of the tympanic membrane and a migration of the accumulation of the keratin in the tympanic cavity.

It can occur at any age. The congenital type is quite uncommon. In the acquired form, there is an history of recurrent
or chronic otitis and history of previous surgery.

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14
Q

Fully describe the clinical manifestation of cholasteatoma

A

These patients usually present with a history of recurrent otitis and with effusion, sometimes glue ear. In the effusion there is usually no infection but there is only a problem of ventilation and so tympanic cavity is filled
with inflammatory fluids

Symptoms can include
- Aural fetid discharge -
frequently related to a super- infection of anaerobes or Pseudomonas
- Hearing loss (conductive or mixed)
- Pain is not typical (chronic perforation

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15
Q

Describe the diagnosis and treatment of cholesteatoma

A

Diagnosis

  • Otomicroscopy
  • CT scan (when cholestatoma is not directly visible, also allows to see the size)

Treatment
- Surgery with a retro-auricular access

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16
Q

Fully describe ALL the complications of cholesteatoma (and their diagnoses)

A

Complications are related to a bacterial or direct cholesteatoma invasion to adjacent structures.
Otitis media with cholesteatoma is associated with more complications, followed by chronic suppurative otitis media and then acute otitis media.

Remember that when you find a complication you have to look for another one. There is an high
percentage of synchronous complication

Complications are classified in three types:

  1. Intracranial bone complications
  2. Temporal bone complications
  3. Vascular complications
TEMPORAL BONE COMPLICATIONS
These are the most common: They include
- Mastoiditis
- Labrynthitis
- Facial nerve palsy

Mastoiditis
Most common temporal bone complication. Mastoid air cells become infected. It is influenced by the virulence of the infective organisms, the immunological status of the patients and also the anatomical situation. (We consider infants as a group of immunocompromised pts - system not yet developed)

Mastoiditis occurs when the when the aditus to antrum becomes obstructed by inflammation. The pressure generated by the purulent secretions within the mastoid, is relieved by egress through the cribiform area or the tympanomastoid fissure, resulting in inflammation and tenderness in the postauricular sulcus.

Diagnosis is clinical:
- Retro-auricular swelling
- Prominent auricle
- Narrowed external ear canal
Usually there is fever, pain and ear discharge
If we submit a patient to otomicroscope evaluation, we find a selective swelling of the posterosuperior portion of the external auditory canal.

Labryrinthitis
This is an infection of the inner ear. It may be:
- suppurative (bacterial)
- serous (non-bacterial)

Clinical picture:

  • Severe vertigo
  • Nystagmus
  • Sensorineural hearing loss
  • in some pts it can spead to subarachnoid space and cause meningitis

Treatment
Surgery is required IMMEDIATELY, because it could lead to the ossification of the inner ear -> permanent damage.

If the affected ear was the only hearing ear we can perform a cochlear implant. (ONLY if ossification has not occured)

Facial palsy
The tympanic portion is the most affected part of the nerve as it passes through the tympanic cavity

VASCULAR COMPLICATIONS
Lateral sinus 
• Thrombophlebitis
• Internal Jugular Vein Thrombophlebitis
• Cavernous Sinus thrombophlebitis 
Thrombophlebitis most commonly affecting one of the two Sigmoid sinuses.
INTRACRANIAL COMPLICATIONS
• Meningitis ( second most common)
• Subdural Empyema
• Extradural abscess
• Cerebral abscess
• Encephalitis

Headache is a clinical symptom that leads to a high suspicion of intracranial complications followed by vomiting without nausea and papilledema, the typical symptoms of endocranial hypertension. Moreover it can be present also the Gardenigo syndrome characterized by the involvement of the first two branches of the trigeminal nerve and in the involvement of the fourth cranial nerve with the result of diplopia.

Note:
Pediatric patients, immigrants, aged, immunocompromised, all of these are possible target to ear complications. Usually they are related to multi drug resistance bacteria and when we do suspect an otogenic hearing complication with clinical signs of mastoiditis, vertigo and worsening of hearing, facial nerve palsy, headache and neck stiffness, CT is required