AUBF 2 CIULLA Flashcards
- Why is the first-voided morning urine
specimen the most desirable specimen for
routine urinalysis?
A. Most dilute specimen of the day and
therefore any chemical compounds
present will not exceed the detectability
limits of the reagent strips
B. Least likely to be contaminated with
microorganisms because the bladder is
a sterile environment
C. Most likely to contain protein because
the patient has been in the orthostatic
position during the night
D. Most concentrated specimen of the
day and therefore it is more likely that
abnormalities will be detected
D. Most concentrated specimen of the
day and therefore it is more likely that
abnormalities will be detected
- The physical characteristic of color
is assessed when a routine urinalysis
is performed. What substance is
normally found in urine that is principally
responsible for its yellow coloration?
A. Bilirubin
B. Melanin
C. Carotene
D. Urochrome
D. Urochrome
- In certain malignant disorders, what
substance is found in the urine that turns
the urine dark brown or black on exposure
of the urine to air?
A. Urobilinogen
B. Indican
C. Melanin
D. Porphyrin
C. Melanin
- What is the expected pH range of a freshly voided urine specimen?
A. 3.5-8.0
B. 3.5-9.0
C. 4.0-8.5
D. 4.5-8.0
D. 4.5-8.0
- Urine specimens should be analyzed as
soon as possible after collection. If urine
specimens are allowed to stand at room
temperature for an excessive amount of
time, the urine pH will become alkaline
because of bacterial decomposition of
A. Protein
B. Urea
C. Creatinine
D. Ketones
B. Urea
- Which term is defined as a urine volume
in excess of 2000 mL excreted over a
24-hour period?
A. Anuria
B. Oliguria
C. Polyuria
D. Hypersthenuria
C. Polyuria
- The reagent test strips used for the
detection of protein in urine are most
reactive to
A. Albumin
B. Hemoglobin
C. Alpha-globulins
D. Beta-globulins
A. Albumin
- A urine specimen that exhibits yellow
foam on being shaken should be suspected
of having an increased concentration of
A. Protein
B. Hemoglobin
C. Bilirubin
D. Nitrite
C. Bilirubin
- How should controls be run to ensure the
precision and accuracy of the reagent test
strips used for the chemical analysis of
urine?
A. Positive controls should be run on a
daily basis and negative controls when
opening a new bottle of test strips.
B. Positive and negative controls should
be run when the test strips’ expiration
date is passed.
C. Positive and negative controls should
be run on a daily basis.
D. Positive controls should be run on a
daily basis and negative controls on a
weekly basis.
C. Positive and negative controls should
be run on a daily basis.
- The colorimetric reagent strip test for
protein is able to detect as little as 5-20 nig
of protein per deciliter. What may cause a
false-positive urine protein reading?
A. Uric acid concentration is greater than
0.5 g/day.
B. Vitamin C concentration is greater
than 0.5 g/day.
C. Glucose concentration is greater than
130mg/day.
D. pH is greater than 8.0.
D. pH is greater than 8.0.
- “Isosthenuria” is a term applied to a series of urine specimens from the same patient that exhibit a
A. Specific gravity of exactly 1.000
B. Specific gravity less than 1.007
C. Specific gravity greater than 1.020
D. Fixed specific gravity of approximately
1.010
D. Fixed specific gravity of approximately
1.010
- A urine specimen is tested by a reagent
strip test and the sulfosalicylic acid test to
determine whether protein is present. The
former yields a negative protein, whereas
the latter results in a reading of 2+
protein. Which of the following statements
best explains this difference?
A. The urine contained an excessive
amount of amorphous urates or
phosphates that caused the turbidity
seen with the sulfosalicylic acid test.
B. The urine pH was greater than 8,
exceeding the buffering capacity
of the reagent strip, thus causing
a false-negative reaction.
C. A protein other than albumin must be
present in the urine.
D. The reading time of the reagent strip
test was exceeded (the reading being
taken at 2 minutes), causing a falsenegative
reaction to be detected.
C. A protein other than albumin must be
present in the urine.
- Which of the following is the major
organic substance found in urine?
A. Sodium
B. Potassium
C. Glucose
D. Urea
D. Urea
- Each of the following is included in the
quality assurance program for a urinalysis
laboratory. Which one represents a
preanalytical component of testing?
A. Setting collection guidelines for
24-hour urines
B. Setting a maintenance schedule for
microscopes
C. Reporting units to be used for crystals
D. Requiring acceptable results for
control specimens before any patient
results are reported out
A. Setting collection guidelines for 24-hour urines
- The presence of ketone bodies in urine
specimens may be detected by use of a
reagent strip impregnated with sodium
nitroprusside. This strip test is sensitive
to the presence of
A. Acetoacetic acid and betahydroxybutyric
acid
B. Acetoacetic acid and acetone
C. Diacetic acid and beta-hydroxybutyric
acid
D. Beta-hydroxybutyric acid and acetone
B. Acetoacetic acid and acetone
- A routine urinalysis is performed on a
young child suffering from diarrhea. The
reagent test strip is negative for glucose
but positive for ketones. These results may
be explained by which of the following
statements?
A. The child has Type 1 diabetes mellitus.
B. The child is suffering from lactic
acidosis, and the lactic acid has falsely
reacted with the impregnated reagent
area for ketones.
C. The child is suffering from increased
catabolism of fat because of decreased
intestinal absorption.
D. The reagent area for ketones was read
after the m
C. The child is suffering from increased
catabolism of fat because of decreased
intestinal absorption.
- The principle of the colorimetric reagent strip test for hemoglobin is based on the peroxidase activity of hemoglobin in
catalyzing the oxidation of a dye with
peroxide to form a colored compound.
This method may yield false-positive
results for the presence of hemoglobin
when the urine specimen contains
A. Ascorbic acid
B. Tetracycline
C. Myoglobin
D. Nitrite
C. Myoglobin
- A reagent test strip impregnated with
a diazonium salt such as diazotized
2,4-dichloroaniline may be used to
determine which analyte?
A. Glucose
B. Ketone
C. Hemoglobin
D. Bilirubin
D. Bilirubin
- Which of the following will contribute to a specimen’s specific gravity if it is present
in a person’s urine?
A. 50-100 RBC/hpf
B. 85 mg/dL glucose
C. 3+ amorphous phosphates
D. Moderate bacteria
B. 85 mg/dL glucose
- With infections of the urinary system,
white blood cells are frequently seen in
the urine sediment. What type of white
blood cell is seen the most frequently in
urine sediment?
A. Eosinophil
B. Lymphocyte
C. Monocyte
D. Neutrophil
D. Neutrophil
- A random urine is collected from a patient and the results obtained are as follows: urine albumin =16 mg/dL and urine
creatinine = 140 mg/dL. These findings are consistent with
A. Microalbuminuria
B. Macroalbuminuria
C. Nephrotic syndrome
D. Obstructive jaundice
A. Microalbuminuria
- To detect more easily the presence of casts in urine sediments, which microscopic
method can be used?
A. Fluorescent microscopy
B. Phase-contrast microscopy
C. Polarized microscopy
D. Brightfield microscopy
B. Phase-contrast microscopy
- Which substance found in urinary
sediment is more easily distinguished
by use of polarized microscopy?
A. Lipids
B. Casts
C. Red blood cells
D. Ketone bodies
A. Lipids
- “Glitter cell” is a term used to describe
a specific type of
A. Ketone body
B. Oval fat body
C. Fatty droplet
D. Neutrophil
D. Neutrophil
- The final phase of degeneration that
granular casts undergo is represented
by which of the following casts?
A. Fine
B. Coarse
C. Cellular
D. Waxy
D. Waxy
- A 40-year-old female patient with a history
of kidney infection is seen by her physician
because she has felt lethargic for a few
weeks. She has decreased frequency of
urination and a bloated feeling. Physical
examination shows periorbital swelling
and general edema, including a swollen
abdomen. Significant urinalysis results
show the following: color = yellow;
appearance = cloudy/frothy; specific
gravity = 1.022;pH = 7.0; protein =
4+; 0-3 WBC/hpf; 0-1 RBC/hpf; 0-2
renal epithelial cells/hpf; 10-20 hyaline
casts/lpf; 0-1 granular casts/lpf; 0-1 fatty
casts/lpf; occasional oval fat bodies. Her
serum chemistries show significantly
decreased albumin, increased urea
nitrogen, and increased creatinine. These
findings suggest which condition?
A. Multiple myeloma
B. Glomerulonephritis
C. Nephrotic syndrome
D. Chronic renal failure
C. Nephrotic syndrome