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S3M3 > Atypical Pneumonias > Flashcards

Atypical Pneumonias Flashcards

1
Q

Atypical Pneumonia

S/S

A

Fever, Dry cough, interstitial pattern of fibronodular infiltrates, less severe than typical pneumonia

Sputum if present is white

Walking pneumonia - on X-ray
Less likely to have pleuritic pain or effusion

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2
Q

Mycoplasma pneumonia

A

2nd most common cause of CAP after strep
Spread by droplets by cough
rarely fatal

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3
Q

Legionella VF

A

LPS endotoxin and flagellin

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4
Q

how is legionella transmitted?

A

Not human to human !
only from environment
Host susceptibility increased in smokers COPD elderly and IC

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5
Q

Legionella Symptoms

A

Dry cough, fever
Abdominal pain and diarrhea common
Easy to confuse with strep pneumonia cause of lung consolidation
other general systemic symptoms for pneumonia

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6
Q

Chlamydia pneumonia - reproduction cycle

A

Reticulate body - osmotically fragile

Elementary body - contagious

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7
Q

Transmission of chlamydia

A

droplets
not seasonal
males more affected
antibodies no use coz it is IC

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8
Q

Chlamydia symptoms

A

Dry cough, sometimes no fever can last for weeks or months

Can also cause pharyngitis bronchitis otitis media and sinusitis

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9
Q

Chlamydophila - diagnosis

A

Serology by microimmunoflurescence
antigen detection
PCR

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10
Q

Chlamydophila and Atherosclerosis

A

Active field of research

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11
Q

Pertussis - VF

A

Adherence by fimbriae. filamentous hemagglutinin, pertactin
Secreted exotoxin - pertussis toxin - elevated intracellular cAMP by ADP-ribosylation of a G protein which acitvated adenyl cyclase

tracheal cytotoxin

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12
Q

Pertussis - pathogenesis

A

Tracheitis and bronchitis with accumulation of mucus, inflammatory cells, bacteria and dead epithelial cells
Intense coughing against closed vocal cords (valsalva maneuver) attempts to expel mucus

Leukocytosis
infection rarely extends to lung to cause pneumonia or otitis media- never cause bacteremia

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13
Q

What are whoops

A

series of short expiratory coughs to expel mucus

inspiratory gasp

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14
Q

Prevention of Whooping Cough

A

Infant vaccine

needs booster for adults

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15
Q

Pertussis vaccine

A

acelular aP is always combined with diptheria and tetanus DTaP
Contains - pertussis toxoid, filamentous hemagllutinin

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16
Q

Chlamydophila and Atherosclerosis

A

Active field of research

17
Q

Pertussis - VF

A

Adherence by fimbriae. filamentous hemagglutinin, pertactin
Secreted exotoxin - pertussis toxin - elevated intracellular cAMP by ADP-ribosylation of a G protein which acitvated adenyl cyclase

tracheal cytotoxin

18
Q

Pertussis - pathogenesis

A

Tracheitis and bronchitis with accumulation of mucus, inflammatory cells, bacteria and dead epithelial cells
Intense coughing against closed vocal cords (valsalva maneuver) attempts to expel mucus

Leukocytosis
infection rarely extends to lung to cause pneumonia or otitis media- never cause bacteremia

19
Q

What are whoops

A

series of short expiratory coughs to expel mucus

inspiratory gasp

20
Q

Prevention of Whooping Cough

A

Infant vaccine

needs booster for adults

21
Q

Pertussis vaccine

A

acelular aP is always combined with diptheria and tetanus DTaP
Contains - pertussis toxoid, filamentous hemagllutinin

22
Q

Chlamydophila and Atherosclerosis

A

Active field of research

23
Q

Pertussis - VF

A

Adherence by fimbriae. filamentous hemagglutinin, pertactin
Secreted exotoxin - pertussis toxin - elevated intracellular cAMP by ADP-ribosylation of a G protein which acitvated adenyl cyclase

tracheal cytotoxin

24
Q

Pertussis - pathogenesis

A

Tracheitis and bronchitis with accumulation of mucus, inflammatory cells, bacteria and dead epithelial cells
Intense coughing against closed vocal cords (valsalva maneuver) attempts to expel mucus

Leukocytosis
infection rarely extends to lung to cause pneumonia or otitis media- never cause bacteremia

25
Q

What are whoops

A

series of short expiratory coughs to expel mucus

inspiratory gasp

26
Q

Prevention of Whooping Cough

A

Infant vaccine

needs booster for adults

27
Q

Pertussis vaccine

A

acelular aP is always combined with diptheria and tetanus DTaP
Contains - pertussis toxoid, filamentous hemagllutinin

S3M3 (11 decks)

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