Atypical Antipsychotics

Question 1

Geodon

Answer 1

Ziprasidone

Question 2

Risperdal

Answer 2

Risperidone

Question 3

Seroquel

Answer 3

Quetiapine

Question 4

Invega

Answer 4

Paliperidone

Question 5

Zyprexa

Answer 5

Olanzapine

Question 6

Abilify

Answer 6

Aripiprazole

Question 7

Latuda

Answer 7

Lurasidone

Question 8

Clozaril

Answer 8

Clozapine

Question 9

Fanapt

Answer 9

Iloperidone

Question 10

Saphris

Answer 10

Asenapine

Question 11

Ziprasidone (Geodon) AEs

Answer 11

BBW- Increased mortality in elderly patients with dementia-related psychosis
abnormal vision, akathisia, asthenia, dizziness, extrapyramidal symptoms (dyskinesia, dystonia, extrapyramidal syndrome, hypertonia, hypokinesia, paralysis, somnolence, tremor, twitching), and vomiting.

Question 12

Risperidone (Risperdal) AEs

Answer 12

BBW: Increased mortality in elderly patients with dementia-related psychosis
Somnolence, Insomnia, Agitation, Anxiety, Headache, Rhinitis, Fatigue, Parkinsonism, Akathisia, Increased appetite, Vomiting, Drooling, Urinary incontinence, Tremor, Nasopharyngitis, Rhinorrhea, Enuresis (1-16%)

Question 13

Quetiapine (Seroquel) AEs

Answer 13

Same BBW
Dizziness (1-18%), Fatigue (3-14%), EPS (1-13%), Increased diastolic blood pressure (41%), Increased triglycerides (8-22%), Increased total cholesterol (7-18%), Increased appetite (2-12%), Constipation (6-11%), Dry mouth (9-44%), Headache (7-21), Somnolence (18-57%)

Question 14

Paliperidone (Invega) AEs

Answer 14

Akathisia, Somnolence, Insomnia, Parkinsonism, Tachycardia, Hyperprolactinemia, Others similar to placebo (eg, headache)

Question 15

Olanzapine (Zyprexa) AEs

Answer 15

Weight gain, dose dependent (5-40%), Hypertriglyceridemia (≤39%), Hypercholesterolemia (≤39%), Somnolence, dose dependent (6-39%), Extrapyramidal symptoms (EPS), dose dependent (15-32%), Xerostomia (9-22%), Weakness (2-20%), Dizziness (4-18%), Accidental injury (12%), Insomnia (12%), Elevated alanine aminotransferase (ALT) level (5-12%), Constipation (9-11%), Dyspepsia (7-11%), Hyperprolactinemia (30%), Hyperglycemia (12.8%)

Question 16

Aripiprazole (Abilify)

Answer 16

BBW: same + Suicidality and antidepressant drugs.
Weight gain (8-30%), Headache (27%), Agitation (19%), Insomnia (18%), Anxiety (17%), Nausea and vomiting (11-15%), Akathisia (10-13%), Lightheadedness (11%), Constipation (10-11%)

Question 17

Lurasidone (Latuda) AEs

Answer 17

BBW: same + Suicidality and antidepressant drugs.
Somnolence, dose related (22%), Akathisia, dose related (15%), Fasting glucose increased (10-14%), Nausea (12%), Parkinsonism (11%)

Question 18

Clozapine (Clozaril) AEs

Answer 18

BBW: Agranulocytosis, Orthostatic hypotension, bradycardia, syncope, Seizures, Myocarditis and cardiomyopathy, Increased mortality in elderly patients with dementia-related psychosis
Hypotension, tachycardia, Fever, sedation, seizures (with high doses), Appetite increase, Constipation, Heartburn, Nausea, Polyphagia, Sialorrhea, Vomiting, Weight gain

Question 19

Asenapine (Saphris) AEs

Answer 19

Somnolence (24%), Headache (12%), Dizziness (11%)