Attention deficit hyperactivity disorders

Question 1

What are the symptoms of ADHD?

Answer 1

Inattention
- Short attention span
- Easily distracted
- Difficulty organising
Hyperactive + impulsive
- Can’t sit still
- Act w/o thinking
- Excessive talking

Question 2

What is the treatment for ADHD?

Answer 2

First line: Methylphenidate OR lisdexamfetamine
- Dexamfetamine - intolerant of long effect profile
ALT: atomoxetine (non-stimulant)

Question 3

What are the side effects of methylphenidate?

Answer 3

Insomnia
Tics + tourettes syndrome
- Caution: Hx
DEC appetite = weight loss
- Monitor: appetite
Growth restriction
- Monitor: height + weight
Psychiatric disorders
- Monitor: psychiatric symptoms
CVS
- Monitor: pulse, BP
- CI: CVD, severe HT, hyperthyroidism

Question 4

What are the interactions of methylphenidate?

Answer 4

INC risk of serotonin syndrome (amfetamines) w/ seratonergic drugs (INC 5HT or act on serotonin 5HT receptors)
- Antidepressants
- MAOB inhibitor (segiline)
- Methadone
- Tramadol