Atropine Flashcards
Atropine Uses
C7 - Dysrhythmias - Bradycardia
DT7 - Organophosphates
DT5 - Nerve Agent Poisoning
Atropine type
Anticholinergic
Atropine contraindications
Nil for NSWAS
Atropine adverse effects 8
Dry mouth
Blurred vision
Tachycardia
Nausea & vomiting
Hyperthermia
Dysrhythmia
Urinary retention
Agitation, delirium, hallucinations, seizure and coma may occur in high doses
Atropine action
Antagonises the parasympathetic effects of acetylcholine on muscarinic receptors resulting in:
1 increase heart rate via increasing intrinsic rate of the SA node and conduction through the AV node
2 reducing smooth muscle contraction resulting in pupillary dilation, reduced GI motility and reduced bladder tone
3 blocks exocrine gland activity causing decreased salivary, bronchial, gastric and sweat secretions
Atropine
Route. Onset Peak Duration
IM
IV
Route. Onset Peak Duration
IM dependent on perfusion
IV <2min. <5min. 2-6hrs
Atropine special notes
As two concentrations are available: Read the label carefully and cross check prior to administration
IM atropine should only be used where IV access is not available
Paediatric bolus dose for Bradycardia may exceed the bolus dose for patients ≥16 years of age
Atropine for Bradycardia
Adult IV dose.
IV 600mcg
Repeat every 1minute
Max 3 milligrams
Atropine Adult Bradycardia IM dose
IM 600mcg
Repeat every three minutes
Max 3 milligrams
Atropine paediatric under what age
<16yo
Atropine paediatric IV/IO for bradycardia dose
20mcg / kilo
No repeat
May exceed adult dose
Atropine paediatric IM for bradycardia dose
20mcg / kilo
No repeat
May exceed adult dose
Atropine adult dose IV for organophosphate poisoning
600mcg undiluted
Repeat every 1 minute
No max
Atropine adult dose IM for organophosphate poisoning
2 mg undiluted
Repeat every 3 minutes
No max
Atropine paed dose IM for organophosphate poisoning
20 mcg / kilo undiluted Max bolus 600 mcg
Repeat every 3 minutes
No max
Atropine paed dose IV/IO for organophosphate poisoning
20 mcg / kilo undiluted bolus
Max bolus 600 mcg
every 1 mins
No max
Atropine indication for organophosphate poisoning
All ages
1heart rate less than 80 per min and/or
2 systolic BP less than 80 and or
3 increased secretions crackles or chest crepitations
Atropine nerve agent poisoning indication
All ages mild nerve agent poisoning
<6yrs moderate to severe nerve agent poisoning
=>6yrs as above if unresponsive to automatic injector or not available
Atropine nerve agent poisoning adult dose IV
600 mcg undiluted
Repeat every 1min
No Max
Atropine nerve agent poisoning adult dose IM
2 mg undiluted
Repeat every 3 min
No max
Atropine nerve agent poisoning 1-16 dose IV/IO
20mcg /kg diluted, Max bolus 600mcg
Repeat every 1min
No Max
Atropine nerve agent poisoning =<1 dose IM
50-100mcg diluted
Repeat every 3 min
No Max
Atropine nerve agent poisoning 1-16 dose IM
20 mcg\ kg undiluted bolus Max bolus 600 mcg
Repeat every 3 min
No max
