Atropine

Question 1

What is Atropine used to treat?

Answer 1

Muscarinic antagonist. Used to treat bradycardia and for ophthalmic applications.

Example sentence: Atropine is commonly used to dilate the pupil during eye examinations.

Question 2

What are the actions of Atropine?

Answer 2

1 pupil dilation, cycloplegia

Bronchodilation, decreases secretions

+ decreases acid secretion

+ decreases motility

+ decreases urgency in cystitis

1 increases body temperature (due to t sweating); t HR;

dry mouth; dry, flushed skin; cycloplegia;

constipation; disorientation

Example sentence: Atropine can cause pupil dilation and dry mouth as adverse effects.

Question 3

What are some adverse effects of Atropine?

Answer 3

body temperature (due to t sweating); † HR; dry mouth; dry, flushed skin; cycloplegia; constipation; disorientation
Can cause acute angle-closure glaucoma in older adults (due to mydriasis), urinary retention in men with prostatic hyperplasia, and hyperthermia in infants

Example sentence: Atropine can cause dry mouth, increased body temperature, and constipation as adverse effects.

Question 4

What are some notes about Atropine?

Answer 4

Blocks muscarinic effects (DUMBBELSS) of anticholinesterases, but not the nicotinic effects

Adverse effects: Hot as a hare, Fast as a fiddle, Dry as a bone, Red as a beet, Blind as a bat, Mad as a hatter, Full as a flask

Atropine blocks muscarinic receptors in the salivary glands, producing dryness of the mouth (xerostomia). Sweat and lacrimal glands are similarly affected. [Note: Inhibition of secretions of sweat glands can cause elevated body temperature, which can be dangerous in children and the elderly

Example sentence: Atropine blocks muscarinic receptors and can cause dryness of the mouth.