Atropine Flashcards

1
Q

How is atropine presented? (4)

A

Pre-filled syringe containing 1mg atropine sulfate in 10ml (100mcg/1ml)
Pre-filled syringe containing 1mg in 5ml (200mcg/1ml)
Pre-filled syringe containing 3mg in 10ml (300mcg/1ml)
Ampoules containing 600mcg in 1ml

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2
Q

What are some indications for the administration of atropine sulfate? (6)

A

Symptomatic bradycardia in the presence of ANY of these adverse signs:

Absolute bradycardia <40bpm
Low systolic BP
Sudden ventricular arrhythmia requiring suppression
Inadequate perfusion causing confusion
Bradycardia following ROSC

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3
Q

What is the most common cause of bradycardia in children?

A

Hypoxia

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4
Q

What is a contraindication for atropine?

A

DO NOT administer to treat bradycardia in suspected hypothermia

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5
Q

What 3 things does atropine do?

A

Reverse effects of vagal overdrive
Increases heart rate
Enhances AV conduction

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6
Q

How does atropine increase heart rate?

A

Blocks vagal activity in sinus bradycardia, second or third degree heart block

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7
Q

What are 6 side effects of atropine?

A

Dry mouth
Visual blurring
Pupil dilation
Confusion
Occasional hallucinations
Tachycardia

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8
Q

What can happen when you administer small doses of atropine <100mcg?

A

Can cause paradoxical bradycardia

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9
Q

Why should atropine not be administered with suspected myocardial infarction?

A

May induce tachycardia which will increase myocardial oxygen demand and worsen ischaemia

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10
Q

When can atropine be administered with suspected MI?

A

If low heart rate is causing problems with perfusion

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11
Q

What is the initial dose of atropine?

A

600mcg

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12
Q

What is the volume of atropine for administration with 600mcg per ml?

A

1ml

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13
Q

What is the volume of atropine to be administered with 300mcg of atropine per ml?

A

2ml

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14
Q

What is the max dose of atropine?

A

3mg

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15
Q

What is the repeat dose for atropine?

A

600mcg

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16
Q

What is the dose interval for atropine?

A

3-5 minutes

17
Q

How should atropine be administered?

A

IV or IO

18
Q

What is the volume of atropine to be administered with 200mcg per ml?

A

3ml

19
Q

What is the volume of atropine to be administered with 100mcg in 1ml?

A

6ml