atrial fibrillation2 Flashcards

1
Q

what are the two long term strategies for AF

A
  1. rhythm control

2. rate control

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2
Q

what is the preferred long term strategy for long term AF?

why?

A

rate control is preferred because drugs are tolerated better (less side effects)

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3
Q

what long term strategy is to leave patient in AF, and protect against complicatoins (stroke and V fib)?

A

rate control

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4
Q

what is the goal heart rate for patients on rate control treatment for AF?

A

110 bpm

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5
Q

what are two main drug classes that control ventricular rate slowing conduction through AV node

A

B-blockers

Ca- channel blockers

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6
Q

why is digoxin not typically prefered for rate control?

A

because act parasympathetically;

won’t work for active people alone (given in combo with BB or CaB)

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7
Q

what is always part of rate control therapy?

A
  1. control ventricular rate

2. protect from stroke

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8
Q

what rate control class would be prefered in a patient with asthma

A

Ca channel blocker

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9
Q

what type of long term treatment of AF has goal of NSR

A

rhythm control

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10
Q

what AF tx drug is not for maintenence therapy, just for cardioversion

A

ibutilide

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11
Q

what must be done in every patient after conversion to NSR

A

4 weeks of anticoagulation minimum

becausing of stunting of myocardial tissue take s a while to recover

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12
Q

what chronic maintenance sinus rhythm control therapy drugs are preferred if no comorditities are present

A

dronedarone
flecainide
propafenone
sotalol

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13
Q

what chronic maintenance sinus rhythm control therapy drugs can’t be used with hypertension and thickining of ventricular walls (LVH)

A

dronedarone
flecainide
propafenone
sotalol

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14
Q

what is catherter ablation?

what type of patients can have this?

A

cathater inserted in groin that burns out any arrhythmia causing tissue.
any patient despite comorbitity

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15
Q

what chronic maintenance sinus rhythm control therapy drug is preferred in patients with hypertension and LVH

A

amiodorone

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16
Q

what chronic maintenance rhythm therapy drug is preferred in patients with coronary artery disease

A

dofetalide

sotalol

17
Q

what chronic maintenance sinus rhythm control therapy drug is preferred in patients with

A

amiodarone

dofetalide

18
Q

what are the two “classic” drugs for decreasing risk of stroke

A

warfarin and aspirin

19
Q

what is the therapeutic range of warfarin?

how much does it decrease the risk of stroke?

A

2-3

decrease risk by 62-68%

20
Q

what is an advantage of aspirin over warfarin?

how much does aspirin decrease the risk of stroke

A

aspirin has less bleeding risk

decreases risk of stroke by 21%

21
Q

what is the combination anticoagulants

A

ASA + clopidogrel

22
Q

list the anticoagulation effects in order of least to most:

warfarin, aspirin, clopidogrel, aspirin + clopidogrel

A

aspirin < aspirin + clopidogrel < warfarin

23
Q

what is the validated model used to predct the risk of eschemic stroke in patients with AF?

A

CHADS2

24
Q

when should CHADS2 be used?

when should it not be used?

A

use w/ chonic AF (rate control or rhythm control tx)

don’t use w/ new onset AF

25
Q

what is the most important predictor of increased risk of stroke

A

previos stroke or TIA (transient ischemic attack)

26
Q

what are the risk factors measured by CHADS2

A

1 congestive heart failure history

  1. hypertension
  2. age over 75
  3. diabetes mellitus
  4. secondary prevention = prior ischemic stroke or TIA (this one is worth 2 points
27
Q

what CHADS score is considered low risk, what kind of antithrombotic treatment should these patients get

A

CHADS score = 0

don’t get any antiplatelets or anticoagulants

28
Q

what drugs should be used on a patient with a CHADS score greater than 1

A

warfarin
dabigitran
rivaroxaban
epixiban

29
Q

what type of risk are people with a CHADS score greater than 1?
what type drug should be used on a patient with this score

A

intermediate to high risk

an oral anticoagulant (not an antithrombic agent