AF3

Question 1

list the antiarrhythmics that risk torsades

Answer 1

All class Ia (quinidine, disopyramide, procainamide)
and sotalol, dofetilide, ibutilide, and amiodorone

Question 2

what drugs can’t be given in combo with aniarrhythmics that risk TDP?

Answer 2

1. amitriptyline (tricyclic)
2. erythromycin and clarithromycin (macrolide)
3. levofloxacin and gatifloxacin (fluoroquinolones)
4. chlorpromazine and thioridazine (antipsychotics)

Question 3

what is the restricted access class III antiarrhythmic

Answer 3

dofetilide

Question 4

what disease states are included in Atherosclerotic CV Disease

Answer 4

coronary heart disease
stroke
peripheral arterial disease

Question 5

what is included in clinical ASCVD

Answer 5

acute coronary syndromes
MI hx
angina
stroke
TIA

Question 6

what anticoagulants should be used for pre-cardioversion anticoagulation

Answer 6

1. warfarin
   lmwh (full dose)
   dabigatran

Question 7

list high intensity statin options

Answer 7

atorvastatin 40-80 mg

rosuvastatin 20-40 mg

Question 8

a patient on amiodarone, amlodipine or ranolazine should not receive more than how much simvastatin

Answer 8

20 mg daily

Question 9

a patient on verapamil or diltiazem should not exceed how much simvastatin daily

Answer 9

10 mg daily

Question 10

what are the determinants of oxygen demand often targeted by drug tx for chd?

Answer 10

1. heart rate
2. contractility
3. systolic wall tension

Question 11

what are the determinants of wall tension

Answer 11

1. systolic or intraventricular pressure (afterload)
2. ventricular size and shape (preload)
3. ventricular wall thickness

Question 12

what determins oxygen supply

Answer 12

1. coronary blood flow
2. oxygen content of arterial blood
3. amount of oxygen extracted by myocardium

Question 13

what is the goal hemoglobin A1C

Answer 13

less than 7

Question 14

what ca blockers increase o2 supply to

Answer 14

diltiazem
verapamil
amlodipine

Question 15

what are the thienopyridines

Answer 15

1. clopidogrel
2. prasugrel
3. ticlopidine

Question 16

what is the moa of thienopyridines

Answer 16

inhibit adp-induced platelet aggregation by blocking adp from recepotr

Question 17

list the glycoprotein inhibitors

what is there moa

Answer 17

abciximab
eptifibatide
tirofiban
inhibit final step in platelet aggregation