Atrial Fibrillation Flashcards

1
Q

What is the condition characterized by irregular pulse?

A

Atrial fibrillation

Atrial fibrillation is associated with various symptoms and can lead to serious complications.

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2
Q

List three symptoms of atrial fibrillation.

A

Irregular pulse with or without:
* Breathlessness
* Fatigue
* Dizziness
* Syncope/fainting
* Palpitations
* Chest discomfort

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3
Q

What is a potential consequence of atrial fibrillation related to blood flow?

A

Can contribute to stroke or heart attack

Blood can pool inside the heart, leading to clot formation.

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4
Q

What are the first-line treatments for atrial fibrillation?

A

(Direct) Oral anticoagulants like dabigatran, apixaban, rivaroxaban, and edoxaban.
And rate control drugs (digoxin)/beta-blockers (propanolol, metoprolol)/calcium channel blockers (diltiazem)

Discuss potential benefits and risks. CHA2DS2-VASc and ORBIT are used.

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5
Q

What is the second-line treatment for atrial fibrillation?

A

Vitamin K antagonists like warfarin, acenocoumarol and phenidione.

If contraindicated, refer to cardiology.

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6
Q

What diagnostic test is primarily used to identify atrial fibrillation?

A

Electrocardiogram (ECG)

Other tests may include echocardiogram, chest x-ray, and blood tests.

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7
Q

List two potential identifiable causes of atrial fibrillation.

A
  • High blood pressure
  • Heart failure

Other causes can include obesity, diabetes, and chronic kidney diseases.

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8
Q

True or False: Atrial fibrillation can be triggered by focal firing within the atria.

A

True

Atrial arrhythmias like atrial flutter can also trigger atrial fibrillation.

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9
Q

What are key contributing factors to atrial fibrillation?

A
  • Electrical remodelling
  • Structural remodelling
  • Cell death
  • Fibrosis

These factors can lead to the development and persistence of atrial fibrillation.

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10
Q

Fill in the blank: Atrial fibrillation can lead to _______ due to blood clot formation.

A

stroke or heart attack

Clots can form in the brain (stroke) or coronary vessels (heart attack) , resulting in serious health issues.

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11
Q

Three types of AF

A

Paroxysmal, persistent and permanent

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12
Q

Do not offer rate control as first line if a person has AF AND

A
  • A potentially reversible cause.
  • Heart failure thought to be primarily caused by AF.
  • New-onset AF within the past 48 hours.
  • A rhythm-control strategy is felt to be more suitable clinically — this will usually be a specialist decision.
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13
Q

When is DOAC considered for first line?

A

if a person has AF and a CHA2DS2-VASc score of 2 or above, and consider a DOAC for a man with AF and a CHA2DS2-VASc score of 1, taking into account the risk of bleeding

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14
Q

Do not offer anticoagulation to…

A

a person aged under 65 years with AF and no risk factors other than their sex (a very low risk of stroke equating to a CHA2DS2-VASc score of 0 for men or 1 for women).

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15
Q

CHA2 DAS2-VASC test

A

Determines a persons stroke risk

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16
Q

ORBIT score

A

bleeding risk score- identify people at high risk of bleeding to help guide decisions on anticoagulation treatment and monitoring