Atopic Dermatitis- Eczema Flashcards
Characteristics of mild atopic dermatitis
Areas of dry skin, infrequent itching (with or without small areas of redness), little impact on everyday activities, sleep, and psychosocial wellbeing
Characteristics of moderate atopic dermatitis
Areas of dry skin, frequent itching, redness (with or without excoriation and localized skin thickening), moderate impact on everyday activities and psychosocial wellbeing, frequently disturbed sleep
Characteristics of severe atopic dermatitis
Widespread areas of dry skin, incessant itching, redness with or without excoriation, extensive skin thickening, bleeding, oozing, cracking, and alteration of pigmentation, severe limitation of everyday activities and psychosocial functioning, nightly loss of sleep
Low potency cream/ointment for mild atopic dermatitis
Desonide 0.05% cream/ointment
High potency cream/ointment for moderate disease
Triamcinolone acetonide ointment 0.5%
Treatment for atopic dermatitis on the face/flexures
Low potency steroids for 5-7 days
Pharmacologic treatment options for severe disease
Tacrolimus (Protopic 0.03% and 0.1%), pimecrolimus (Elidel)
Non-pharmacologic options for severe disease
Soak and smear, wet wraps, phototherapy
Other pharmacologic treatments for atopic dermatitis
Crisaborole (Eucrisa), dupilumab, cyclosporine, methotrexate, azathioprine, MMF, doxepin
Crisaborole (Eucrisa) uses
Topical treatment of mild-moderate atopic dermatitis in patients ≥2 years old
Crisaborole (Eucrisa) MoA
PDE-4 activity
Prevention of atopic dermatitis: eliminating exacerbating factors
Get rid of stress, anxiety, heat, low humidity, contact allergens
Prevention of atopic dermatitis: bathing
Warm, soaking baths or showers, soap-free or mild cleansers
Prevention of atopic dermatitis: maintaining skin hydration
Avoid lotions, use thick creams or ointments at least BID and after hand washing and bathing
Avoid pruritus: pharmacologic therapy
PO antihistamines, especially with concurrent urticaria or rhinoconjunctivitis
