ATI Pharm 2013B Flashcards

1
Q

Allopurinol

A

antigout agent

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2
Q

How does allopurinol interact with warfarin?

A

increases the effects of warfarin by decreasing metabolism. Serious or life-threatening. Risk for bleeding!

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3
Q

Timolol

A

beta blocker to treat glaucoma, contraindicated if patient has bradycardia.

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4
Q

Isosobide mononitrate (monoket)

A

nitrate, treat angina

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5
Q

tranylcypromine (parnate)

A

antidepressant, can cause orthostatic hypotension

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6
Q

what does dopamine do for a patient in shock state?

A

increase blood pressure, it is a catecholamine

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7
Q

What drug reverses heparin toxicity?

A

protamine sulfate

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8
Q

What drug reverses cholinergic toxicity?

A

atropine sulfate

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9
Q

What drug reverses benzodiazapine toxicity?

A

flumazenil (romazicon)

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10
Q

What drug reverses opioid toxicity?

A

Narcan (naloxone)

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11
Q

Methotrexate s/e

A

stomatitis, sores in the mouth

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12
Q

what does lactobacillus acidophilus (Lactinex) do?

A

replace normal flora in the intestines

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13
Q

contraindication to Ciprofloxacin (cipro)

A

Tnedonitis, can exacerbate. have risk of tendon rupture.

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14
Q

Brand name for albuterol

A

Proventil

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15
Q

how does prednisone, a glucocorticoid, affect vaccines?

A

should not get vaccine while taking it b/c it reduces antibody responses and increases risk of infection from live virus vaccines

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16
Q

what does Pilocarpine treat and how long is treatment?

A

tx glaucoma, have to take rest of life.

17
Q

spironolactone

A

K-sparing diuretic, watch for s/s of hyperkalemia (lethargy)

18
Q

What class is enalapril (vasotec) ?

A

ACE inhibitor that retains potassium, monitor K w/ spironolactone

19
Q

How do you administer EpiPen?

A

IM, massage 10 sec afterwards to promote absorption

20
Q

what drug class is amoxicillin (Augmentin)?

A

penicillin

21
Q

what class is cyclosporine?

A

immunosuppressant that can cause nephrotoxicity

22
Q

Acetaminophen overdose

A

more than 4000 mg / day

23
Q

what may zidovudine (Retrovir) cause?

A

severe anemia, monitor hgb

24
Q

Pt who is allergic to penicillin should also not take what drugs?

A

cephalosporins. pt can have cross-reactivity; rare but life-threatening

25
Q

why do cancer patients take pegfilgrastim (Neulasta)?

A

increase WBC count

26
Q

what is an adverse effect of methylphenidate (Ritalin)?

A

weight loss due to appetite suppression

27
Q

A pt with RA taking Prednisone long term should be assessed for what?

A

edema. causes sodium and fluid retention.

28
Q

what is adv effect of gentamicin antibiotic?

A

permanent hearing loss

29
Q

If a pt is taking ACE inhibitor (lisinoPRIL) what must nurse monitor for, and pt must stop the drug?

A

dry cough. it is from buildup of bradykinin

30
Q

when a person administers a nitroglycerin patch to self, when should BP be assessed?

A

1 hour after application.

31
Q

Mannitol

A

diuretic for cerebral edema, can decrease intraocular pressure

32
Q

epoetin alfa (Procrit)

A

stimulates bone marrow production of RBC, so monitor if Hgb increases

33
Q

what can bilateral crackles in the lungs indicate?

A

reduced CO and heart failure

34
Q

when should oxytocin be discontinued?

A

when uterine contractions persist for 60 sec or longer, and if closer than every 2-3 min

35
Q

therapeutic INR range for warfarin?

A

2-3 INR. 3-4.5 is for pt with recurrent systemic embolism

36
Q

what should a pt do after taking risedronate (Actonel)?

A

sit up for 30-60 min to reduce adverse GI effects of esophagitis and dyspepsia

37
Q

What should a pt on lithium avoid?

A

NSAIDs, they increase lithium levels

38
Q

what food allergy puts pt at risk for allergic rxn to contrast medium?

A

shrimp, shellfish

39
Q

what anticholinergic effect does amitriptyline have?

A

urinary retention