Atherosclerosis Flashcards

1
Q

What is the definition of atherosclerosis?

A

Atherosclerosis is the accumulation of intracellular and extracellular lipid int the intima and media of large and medium sized arteries - consequence is the thickening and hardening of arterial walls

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2
Q

What is the definition of arteriosclerosis?

A

The thickening of the walls of arteries and arterioles usually as a result of hypertension or diabetes mellitus

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3
Q

What are some macroscopic features of atherosclerosis?

A
  • Fatty streak
  • Simple plaque
  • Complicated plaque
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4
Q

What is a fatty streak?

A

The first grossly visible lesion in the development of atherosclerosis

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5
Q

Where are the lipid deposits when a fatty streak is seen?

A

In intima

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6
Q

How do fatty streaks appear?

A

Irregular yellow-white discolouration on the luminal surface of an artery

Yellow, slightly raised

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7
Q

What do fatty streaks consist of?

A

Aggregates of foam cells

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