Aterial Blood Gas Flashcards
Acid/Base buffering systems
Bicarb/Carbonic Acid
-Seconds
Lungs blow off/hold CO2
-Minutes
Kidneys resorb/excrete Bicarb
-Hours to days
Acidotic Arterial pH
<7.35
Alkalotic Arterial pH
> 7.45
Perfect pH
7.40
Bicarbonate (HCO3)
(Acidotic) < 22 - 26> (Alkalotic)
Base Excess/deficit
-3 to 3 mEq/L
PaO2
80-100mmHg
40 = 70%
50 = 80%
60 = 90%
SaO2
92-98%
Oxyhemoglobin Dissociation Right Curve
Reduced affinity
Hyperthermia
Acidosis (Sepsis)
Maternal blood (Mom)
Think CrossFit workouts
Oxyhemoglobin dissociation left curve
Loves oxygen
Increased Affinity
Hypothermia
Alkalosis
Fetal blood (baby)
Mixed Disturbance
Both Co2 & HCO3 are offending agents
Metabolic Alkalosis
pH: >7.45
HCO3: >26
Causes of Metabolic Alkalosis
Vomiting
Gastric suctioning
K+ loss due to diuretics, steroid use, or diarrhea
Anti acid overdose
Metabolic Acidosis
pH <7.35
HCO3 <22
Causes of Metabolic Acidosis
Lactic Acidosis
-Sepsis
-Anaerobic metabolism
-Ineffective CO2 clearance caused by malperfusion (cardiac arrest)
Cellular starvation
-DKA, AKA, malnutrition, prolonged seizures, rhabdo
Causes of respiratory Alkalosis
Alveolar hyperventilation
Pain
Pregnancy
High altitude
P.E.
Aspirin OD
Iatrogenic Alkalosis
Over-ventilation caused by medical professionals
Causes of respiratory acidosis
Failure of lungs to eliminate CO2
Hypoventilation
Chest wall injury
CNS depression
Airway obstruction
Cardiac arrests
Critical ABG Thresholds
Severe shock
-pH <7.2
Hypercarbic respiratory failure
-Co2 >55
Hypoxia respiratory failure
-PaO2 <60 (90%)
For every __ of ETCo2, pH will change ___ in the ___ direction
10mmg
0.08
Opposite
For every ___ in pH, HCO3 will change ___ in the _____ direction
.15
10mmol/L
Same
For every ____ in pH, K+ will change ___ in the ____ direction
0.10
0.6 mEqs
Opposite
For every ____ in Co2, K+ will change ____ in the _____ direction
10mmHg
0.5mEqs
Same
Anion gap formula
Na+ - (Cl + HCO3)
CO2 and pH
Co2 up 10 = pH down .08
Bicarb and pH
HCO3 up 10 = ph up 15
Bicarb replacement
Kg/4 x base deficit = mEq of Bicarb needed
Pa02 at altitude
PaO2 drops 5 for every 1000 feet elevation