Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Y1 RESPIRATORY > Asthma > Flashcards

Asthma Flashcards

1
Q

Is asthma an obstructive or restrictive disease?

A

Obstructive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What happens to the basement membrane in remodelling?

A

It thickens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What happens to the submucosa in remodelling?

A

Collagen deposition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What happens to smooth muscle in remodelling?

A

Hypertrophy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Asthmatics usually have a productive cough with wheeze. True/False?

A

False

Cough is usually dry/non-productive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is wheeze?

A

High pitched expiratory sound

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

List the British Thoracic Society drug guidelines for asthma treatment

A
  1. SABA
    • Inhaled steroid
  3. +LTRA
  4. ICS + LABA + LTRA
  5. MART (ICS + LABA) +/- LTRA
    • LAMA/ Theophylline
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

CysLT antagonists (Montelukast) are more potent than inhaled steroids. True/False?

A

False

2nd line additive to inhaled steroid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Cetirizine and Loratidine are sedative antihistamines. True/False?

A

False

They are non-sedative

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What do anti-IgE monoclonal antibody treatments (Omalizumab) do?

A

Prevent binding to IgE receptor and inhibit mediator release from basophils and mast cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What would be PEFR in moderate asthma?

A

Less than 80% predicted

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What would be PEFR in severe asthma?

A

Less than 50% predicted

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What would be PEFR in life threatening asthma?

A

Less than 30% predicted

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Outline management of acute severe asthma

A 
Oxygen (40-60%)
Salbutamol (nebulised)
Hydrocortisone (IV)
Ipratropium (nebulised)
Theophylline (oral)
Magnesium sulphate (IV)
Anaesthetist!
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

List features of an acute-severe asthma attack

A

Unable to finish sentences
PEFR less than 50% predicted
Tachycardia
RR more than 25 breaths/min

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

List features of a life-threatening asthma attack

A

PEFR less than 30% predicted
Bradycardia, hypotension, silent chest
Exhaustion/confusion
Hypoxia, acidosis

17
Q

What drugs are used in the treatment of eosinophillic inflammation?

A

CCS

Cromones

18
Q

What drugs are used to stop the release of mediators, TH2 cytokines?

A

Anti-leukotrienes
Anti-histamines
Anti-IgE
Anti-IL5

19
Q

What drugs are used to treat twitchy SM?

A

Bronchodilators
B2 agonists
Muscarinic antagonists

20
Q

List some triggers of asthma

A 
Cold air
Exercise
Emotion
Pollution
Smoking/ Passive smoking
Drugs - NSAIDS, B Blockers
Allergens
21
Q

List some features of asthma

A 
Episodic SOB
Diurnal variation
Non-productive cough
Wheeze
Associated atopy
Family history
22
Q

List some tools used in the diagnosis of asthma

A

Peak flow
PFTs
Reversibility with salbutamol
Provocation testing

Y1 RESPIRATORY (12 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions