Asthma Flashcards
Severe asthma PEF?
<33%
severe asthma signs?
silent chest, normal PCO2
2 types of asthma?
slow onset and quick onset
slow onset mediation, sx, tx?
mucus, eosinophil, less responsive to dilators
quick onset mediation, sx, tx?
neutrophil, wheezing, responsive to dilators
RF for increased mortality in asthma?
prior intubation, frequent attack, low socioeconomic status, drug use, comorbidities
how does hyperinflation worsen dead space?
distended alveoli compress capillaries
how does hyperinflation reduce BP?
decreased venosu return
albuterol dosing for severe exacerbation?
2.5-5mg q20 min x 3 doses
lacatte production from albuterol?
increased glycosis with inc FFA and pyruvate
steroids MOA in asthma?
NF Kappa beta transcription system
magensium MOA in asthma?
decreases calcium influx into smooth muscle