Associated diseases with diabetes Flashcards
What are the main diseases associated with diabetes mellitus?
- Cystic fibrosis
- DIDMOAD/Wolfram syndrome
- Bardet-Biedl syndrome
- Coeliac disease
- Thyroid disease
- Polyglandular endocrinopathy
What are the common diseases associated with type 1 diabetes?
- Thyroid disease
- Coeliac
- Pernicious anaemia
- Addison’s
- IgA deficiency
How common is diabetes in patients with cystic fibrosis?
Common
More than 25% have diabetes by the age of 20yrs
What therapy is preferred in patients with cystic fibrosis and diabetes?
Insulin therapy
In cystic fibrosis, what should you screen for from the age of 10yrs?
Diabetes using OGTT
What is another name for DIDMOAD?
Wolfram syndrome
What are the symptoms of Wolfram syndrome?
- Diabetes insipidus
- Diabetes mellitus
- Optic atrophy
- Deafness
- Neurological abnormalities
- Renal problems
- Chronic fatigue
What is Wolfram syndrome?
A rare genetic condition
What doe optic atrophy cause?
Colour-blindness and gradual loss of vision
What are the neurological abnormalities associated with Wolfram syndrome?
- Loss of balance
- Sudden muscle jerks
- Loss of taste and smell
- Depression
What are the renal problems associated with Wolfram syndrome?
- Bedwetting
- Needing to pass urine frequently
- Loss of bladder control
What is the treatment of Wolfram syndrome?
There is no cure or specific treatment
Treat the symptoms and associated diseases
What is Bardet-Biedl syndrome?
Autosommal recessive multisystem genetic disorder
What are the symptoms of Bardet-Biedl syndrome?
- Often very obese
- Polydactyl
- Hypogonadal
- Visual and hearing impairments
- Mental retardation
- Diabetes
- Consanguineous parents
Define consangineous parents
Parents who are relatives of each other (2nd cousins or closer)
