Asprin

Question 1

Class

Answer 1

Platelet Inhibitor, anti inflammatory agent

Question 2

Mechanism of action

Answer 2

Prevents the formation of thromboxane A2, which causes platelets to clump together ( aggregate l) and form plugs that causes obstruction or constriction; has antipyretic and analgesic properties

Question 3

Indications

Answer 3

New onset of discomfort suggestive ACS

Question 4

Contraindications

Answer 4

Hypersensitivity. Relativity contraindicated in patients with active ulcer disease or asthma

Question 5

Adverse reactions / side effects

Answer 5

Bronchospasm, anaphylaxis, wheezing in allergic patient, prolonged bleeding, GI bleeding, epigastric distress, nausea, vomiting, heartburn, reye syndrome

Question 6

Drug interactions

Answer 6

Use with caution in patients allergic to NSAIDS

Question 7

Adult dose / route

Answer 7

160 mg to 325 mg PO. Chewing is preferable in swallowing

Question 8

Pedi dose / route

Answer 8

Not recommended

Question 9

Duration of action

Answer 9

Onset : 5 to 30 minutes. Peak effect: 1 to 3 hours. Duration 3 to 6 hours

Question 10

Pregnancy class

Answer 10

D

Question 11

Special consideration

Answer 11

If there are no contraindications, non enteric coated, chewable aspirin should be given as soon as possible to all patients with a suspect ACS as soon as possible after symptoms onset.