Aspergillus Flashcards
1
Q
ABPA
A
due to HYPERSENSITIVITY reaction to Aspergillus
1-2% prevalence in asthma
2-15% in Cystic Fibrosis
cough brown plugs
2
Q
ABPA Radiology
A
multilobar bronchiectasis
mucoid impaction
mosaic attenuation
tree in bud opacities
3
Q
ABPA Diagnosis
A
asthma xray with fleeting infiltrates Central Bronchiectasis Peripheral Blood Eosinophilia IGG to Aspergillus Increase IGE levels > 1000 A fumigatus IGG and IGE POSITIVE skin reaction to aspergillus antigen
4
Q
ABPA TREAMENT
A
GLUCOCORTICOIDS mainstay
ADD itraconzaole for relapse