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CLTM Prep > ASM [Antiseizure Medications]/ Treatments > Flashcards

ASM [Antiseizure Medications]/ Treatments Flashcards

2020 AES Summary of ASM in the United States + (69 cards)

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1
Q

adrenocorticotropic
hormone
(ACTH)

A

epileptic spasms

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2
Q

BRAND NAME of:
clonazepam
(CZP)

A

Klonapin

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3
Q

clonazepam (CZP) | Klonapin
FDA approved to treat…

A

LGS, myoclonic and absence seizures

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4
Q

BRAND NAME of:
felbamate
(FBM)

A

Felbatol

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5
Q

felbamate (FBM) | Felbatol
FDA approved to treat …

A

Adult refractory focal seizures
Adjunctive treatment in LGS

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6
Q

BRAND NAME of:
everolimus
(EVL)

A

Zortress, Afinitor

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7
Q

everolimus (EVL) | Zortress, Afinitor
FDA approved to treat …

A

Adjunctive Treatment Tuberous Sclerosis Complex assoc. focal Seizures

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8
Q

BRAND NAME of:
clobazam
(CLB)

A

Onfi

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9
Q

clobazam (CLB) | Onfi
FDA approved to treat …

A

Adjunctive Treatment for LGS

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10
Q

BRAND NAME of:
rufinamide
(RUF)

A

Banzel

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11
Q

rufinamide (RUF) | Banzel
FDA approved to treat …

A

Adjunctive Treatment for LGS

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12
Q

BRAND NAME of:
vigabatrin
(VGB)

A

Sabril

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13
Q

vigabatrin (VGB) | Sabril
FDA approved to treat …

A

Monotherapy: Epileptic Spasms
Adjunctive Therapy: Refractory FIAS (Focal Impaired Awareness Seizures)

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14
Q

BRAND NAME of:
fenfluramine
(FEN)

A

Fintepla

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15
Q

fenfluramine (FEN) | Fintepla
FDA approved to treat …

A

Dravet Syndrome

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16
Q

BRAND NAME of:
stiripentol
(STP)

A

Diacomit

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17
Q

stiripentol (STP) | Diacomit
FDA approved to treat …

A

Dravet Syndrome
as Adjunctive Treatment with clobazam

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18
Q

BRAND NAME of:
cannabidiol
(CBD)

A

Epidiolex

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19
Q

cannabidiol (CBD) | Epidiolex
FDA approved to treat …

A

Seizures associated with: LGS, Tuberous Sclerosis Complex, Dravet Syndrome

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20
Q

BRAND NAME of:
carbamazepine
(CBZ)

A

Tegretol

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21
Q

carbamazepine (CBZ) | Tegretol
FDA approved to treat …

A

Focal onset sz, GTC sz, mixed sz types

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22
Q

BRAND NAME of:
topirmate
(TPM)

A

Topamax

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23
Q

topirmate (TPM) | Topamax
FDA approved to treat …

A

Focal onset & GTC sz
Adjunctive treatment in LGS

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24
Q

BRAND NAME of:
valproic acid & divalproex sodium
(VPA)

A

Depakene, Depakote

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25
valproic acid & divalproex sodium (VPA) | Depakene, Depakote FDA approved to treat ...
Monotherapy: focal onset & absence sz Adjunctive treatment: multiple sz types, including absence
26
BRAND NAME of: primidone (PRM)
Mysoline
27
primidone (PRM) | Mysoline FDA approved to treat ...
Monotherapy: focal onset and Tonic Clonic sz's
28
BRAND NAME of: phenytoin (PHT)
Dilantin
29
BRAND NAME of: fosphenytoin (FOS)
Cerebyx
30
Difference between phenytoin and fosphenytoin
-phenytoin is an oral med -fosphenytoin is the IV formulation (used for status epilepticus and for short-term use when unable to give meds orally)
31
phenytoin (PHT), fosphenytoin (FOS) | Dilantin, Cerebyx FDA approved to treat ...
focal onset & GTC seizures
32
BRAND NAME of: phenobarbital (PB)
Luminal
33
phenobarbital (PB) | Luminal FDA approved to treat ...
Focal & Generalized Onset seizures
34
BRAND NAME of: perampanel (PER)
Fycompa
35
perampanel (PER) | Fycompa FDA approved to treat ...
Focal Onset seizures Adjunctive treatment for Primary GTC sz
36
BRAND NAME of: levetiracetam (LEV)
Keppra
37
levetiracetam (LEV) | Keppra FDA approved to treat ...
Focal onset seizures Adjunctive Treatment: myoclonic sz in JME, primary Tonic Clonic seizures
38
BRAND NAME of: lamotrigine (LTG)
Lamictal
39
lamotrigine (LTG) | Lamictal FDA approved to treat ...
Withdrawal to monotherapy: Focal Onset Adjunctive Treatment: Focal onset, LGS, primary Tonic Clonic Seizures
40
BRAND NAME of: ethosuximide (ESM)
Zarontin
41
ethosuximide (ESM) | Zarontin FDA approved to treat ...
Absence Seizures
42
BRAND NAME of: brivaracetam (BRV)
Briviact
43
brivaracetam (BRV) | Briviact FDA approved to treat ...
Focal onset sz
44
BRAND NAME of: gabapentin (GBP)
Neurontin
45
gabapentin (GBP) | Neurontin FDA approved to treat ...
Adjunctive treatment for focal seizures
46
BRAND NAME of: eslicarbazepine (ESL)
Aptiom
47
eslicarbazepine (ESL) | Aptiom FDA approved to treat ...
Focal onset seizures
48
BRAND NAME of: cenobate (CNB)
Xcapri, Ontozry
49
cenobate (CNB) | Xcapri, Ontozry FDA approved to treat ...
Focal onset seizures
50
BRAND NAME of: zonisamide (ZNS)
Zonegran
51
zonisamide (ZNS) | Zonegran FDA approved to treat ...
Adjunctive treatment for focal onset seizure
52
BRAND NAME of: tiagabine (TGB)
Gabitril
53
tiagabine (TGB) | Gabitril FDA approved to treat ...
Adjunctive treatment for focal onset seizures
54
BRAND NAME of: pregablin (PGB)
Lyrica
55
pregablin (PGB) | Lyrica FDA approved to treat ...
Adjunctive treatment for focal onset seizures
56
BRAND NAME of: oxycarbazepine (OXC)
Trileptal
57
oxycarbazepine (OXC) | Trileptal FDA approved to treat ...
Focal onset seizures
58
BRAND NAME of: lacosamide (LCM)
Vimpat
59
lacosamide (LCM) | Vimpat FDA approved to treat ...
Focal onset seizures
60
Broad Spectrum ASMs (treat both focal and gen. onset sz)
brivaracetam (BRV) | Briviact clobazam (CLB) | Onfi felbamate (FBM) | Felbatol lamotrigine (LTG) | Lamictal levetiracetam (LEV) | Keppra perampanel (PER) | Fycompa rufinamide (RUF) | Banzel topirmate (TPM) | Topamax valproic acid & divalproex sodium (VPA) | Depakene, Depakote zonisamide (ZNS) | Zonegran
61
Narrow Spectrum ASMs (treat focal onset sz)
carbamazepine (CBZ) | Tegretol cenobate (CNB) | Xcapri, Ontozry eslicarbazepine (ESL) | Aptiom gabapentin (GBP) | Neurontin lacosamide (LCM) | Vimpat oxycarbazepine (OXC) | Trileptal phenobarbital (PB) | Luminal phenytoin (PHT) | Dilantin pregablin (PGB) | Lyrica primidone (PRM) | Mysoline stiripentol (STP) | Diacomit tiagabine (TGB) | Gabitril vigabatrin (VGB) | Sabril
62
ASM for absence sz
ethosuximide (ESM) | Zarontin
63
This AMS may worsen or precipitate myoclonic sz
lamotrigine (LTG) | Lamictal
64
These AMS have a potential to worsen certain generalized sz types
eslicarbazepine (ESL) | Aptiom gabapentin (GBP) | Neurontin oxycarbazepine (OXC) | Trileptal tiagabine (TGB) | Gabitril vigabatrin (VGB) | Sabril
65
Tell me about the ketogenic diet
The classic ketogenic diet (CKD) consists of a high-fat and low-protein and carbohydrate diet, with restricted calories and fluids. The diet mimics the fasting state, altering the metabolism to use fats as a primary fuel source; catabolism of fatty acids in the liver produces ketone bodies (KB), which induces urinary ketosis.
66
Besides medication what other epilepsy treatment options are there?
Ketogenic diet, VNS (vagal nerve stimulator), DBS (deep brain stimulator), RNS (responsive neurostimulator)
67
Bensodiazepines reduce
REM sleep
68
Phenytoin at toxic levels makes EEG:
Slows alpha frequency to theta range At higher toxicity levels delta activity appears.
69
Side effect of phenytoin [PHT]
Gum hypertrophy and coarsening of facial features

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