ASAP Flashcards
Steps for an electrical signal to transfer across and synapse
Action Potential Arrival
Calcium Influx
Neurotransmitter Release
Neurotransmitter Diffusion
Binding to Receptors
Postsynaptic Response
Postsynaptic Integration
Calcium Influx
Voltage-gated calcium channels open, allowing calcium ions to enter the presynaptic terminal.
Neurotransmitter Release
Calcium influx triggers the release of neurotransmitters from synaptic vesicles into the synaptic cleft.
Neurotransmitter Diffusion
Neurotransmitters diffuse across the synaptic cleft and bind to receptors on the postsynaptic membrane.
Binding to Receptors
Neurotransmitters bind to specific receptors, inducing conformational changes in the receptor proteins.
Postsynaptic Response
Depending on the type of receptor and neurotransmitter, the postsynaptic response can be either excitatory (EPSP) or inhibitory (IPSP).
Postsynaptic Integration
The sum of EPSPs and IPSPs determines whether an action potential is generated in the postsynaptic neuron.
Dorsal Column-Medial Lemniscal Pathway
Carries touch, vibration, proprioception, and fine touch information.
Anterolateral (Spinothalamic) Pathway
Carries pain, temperature, and crude touch information.
Trigeminal Pathway
Carries sensation from the face.
Spinocerebellar Pathway
Carries proprioceptive information from the muscles, tendons, and joints to the cerebellum
beta 1 vs beta 2 receptors
beta 1 = heart
beta 2= bronchioels and arteries
alpha 1 vs alpha 2
alpha 1= Excitatory, found in smooth muscle of blood vessels and the eye
alpha 2=Generally inhibitory, found in the presynaptic terminals of adrenergic neurons. like digestion
Hydrostatic Pressure
Hydrostatic pressure is the pressure exerted by a fluid at equilibrium at a given point within the fluid, due to the force of gravity.
Colloid Osmotic Pressure
the osmotic pressure exerted by proteins, notably albumin, in the blood plasma. It is created by the presence of large, non-diffusible molecules, which cannot cross the capillary wall.
