AS91159 - Gene Expression Flashcards

1
Q

Anticodon

A

Three consecutive bases on the tRNA

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2
Q

Codon

A

Three consecutive bases on the mRNA

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3
Q

Deletion Mutation

A

A mutation on the DNA where a bases(s) is removed, resulting in a frame shift

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4
Q

DNA

A

Double stranded, helix shaped large molecule

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5
Q

Enzyme

A

A protein which acts as a biological catalyst to speed up the rate of chemical reaction in an organism

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6
Q

Frameshift

A

Change in bases that the ribosome reads

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7
Q

Gene

A

A piece of DNA which codes for the making of a protein/feature

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8
Q

Gene

A

A section of DNA which codes for the making of protein

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9
Q

Gene Expression

A

The process where the instructions on our DNA are converted into a functional protein, includes transcription, translation and protein folding

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10
Q

Genotype

A

The genetic make-up of an organism for a feature

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11
Q

Insertion Mutation

A

The mutation on the DNA where a base(s) is added resulting in a frame shift

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12
Q

Metabolic Pathway

A

A series of enzyme-controlled reactions, where the product of one reaction becomes the substrate of the next reaction

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13
Q

Missense Mutation

A

A change of the base on the DNA which codes for a different amino acid. This may or may not alter the shape of the protein and there it’s function.

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14
Q

mRNA

A

Messenger RNA. Made during transcription in the nucleus. Carries the instructions to the ribosome to make a polypeptide chain. CONTAINS CODONS

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15
Q

Mutagen

A

Environmental factor which causes the mutation e.g. agent orange, X-rays, etc

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16
Q

Mutation

A

A permanent change in the bases on the DNA

17
Q

Non-Sense Mutation

A

A change of the base on the DNA which changes the instructions, so a STOP codon occurs in the wrong place. Protein is greatly affected

18
Q

Peptide Bond

A

Bond formed between 2 amino acids during translation

19
Q

Phenotype

A

The physical appearance of a feature

20
Q

Point Mutation

A

A change of only one or a few bases on the DNA

21
Q

Protein

A

A substance made up of many amino acids joined together to form a polypeptide chain, which gets folded into a functional protein (enzymes are a type of protein)

22
Q

Redundancy

A

The fact that multiple codons code for the same amino acid, e.g. CCU, CCC, CCA, and CCG all code for the amino acid Pro

23
Q

RNA

A

Ribonucleic acid. A with U, G with C. Three types, tRNA, mRNA, and rRNA. Single stranded and shorter than DNA. Sugar is ribose.

24
Q

Same-Sense Mutation

A

A change of the base on the DNA where the bases still code for the same amino acid. This is due to the redundancy of the genetic code .

25
Q

Silent Mutation

A

A mutation that is neither favorable nor harmful, that remains in a population.

26
Q

Start Codon

A

The start signals on the mRNA which initiates translation. ALWAYS AUG - Methionine

27
Q

Stop Codon

A

These 3 codons on the mRNA (UAA, UAG, UGA) do not code for an amino acid, therefore, telling the ribosome where to stop translation.

28
Q

Substitution Mutation

A

A mutation where the base(s) on the DNA are swapped

29
Q

Transcription

A

The process by which DNA going to mRNA, occurs in the nucleus. Controlled by RNA polymerase.

30
Q

Translation

A

The process by which DNA going to mRNA, occurs in the cytoplasm on the ribosome.

31
Q

Triplet

A

Three consecutive bases on the DNA

32
Q

tRNA

A

Transfer RNA. Carries an amino acid to the ribosome. 3 Bases on the mRNA = and anticodon.