Arthrose Flashcards

1
Q

constituants cartilage hyalin?

A
  • MEC (eau, collagène II, protéoglycannes)

- chondrocytes

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2
Q

composition liquide synovial?

A
  • eau
  • produits plasma
  • acide hyaluronique
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3
Q

synoviale définition?

A

tissu conjonctif vascularisé revêtu par une couche de synoviocytes sécrétant du liquide synovial

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4
Q

2 zones les plus touchées par l’arthrose?

A

1) cervicales

2) lombaires

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5
Q

arthrose définition?

A

patho détruisant le cartilage et l’os sous-chondral

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6
Q

mécanisme arthrose?

A

1) rupture fibres de collagène
2) hyperplasie chondrocytaire
3) hyperactivité ostéoblastique avec fibrose (lieu de nécroses)
4) hypertrophie synoviale (devient épaisse avec vx congestionnés, infiltrats inflammatoires)

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7
Q

types d’arthroses

A
  • mécaniques (hyperpression)

- structurales = sous-chondrales (altération matrice cartilage)

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8
Q

4 pathos rhumatismales?

A
  • PR
  • spondylarthrite ankylosante
  • arthrite psoriasique
  • arthrite lupique
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9
Q

Quel est le seul signe histologique d’une PR?

A

des nodules rhumatoïdes

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10
Q

types de pathologies infectieuses? x2

A
  • infections à pyogènes (arthrite aigue purulente, septique, à piquants)
  • infections granulomateuses (arthrite tuberculeuse)
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11
Q

dépôts goutte?

A

cristaux d’urate de sodium

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12
Q

dépôts chondrocalcinose?

A

cristaux de pyrophosphate de calcium

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13
Q

types arthropathies métaboliques?

A

1) goutte

2) chondrocalcinose

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