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MSK Patrick Stenhouse > Arthritis Classifications and Auto-immunity > Flashcards

Arthritis Classifications and Auto-immunity Flashcards

1
Q

Arthritis can be classified into which two main categories?

A
  1. Inflammatory
  2. Non-inflammatory
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2
Q

What are the four types of inflammatory arthritis?

A
  1. Seropositive
  2. Seronegative
  3. Infectious
  4. Crystal induced
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3
Q

What are the five types of seropostive inflammatory arthritis?

A
  1. Rheumatoid arthritis
  2. Lupus
  3. Scleroderma
  4. Vasculitis
  5. Sjogren’s
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4
Q

What are the four types of seronegative inflammatory arthritis?

A
  1. Anklosing spondylitis
  2. Psoriatic arthritis
  3. Reactive arthritis
  4. Inflammatory bowel (enteropathic) arthritis
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5
Q

What are seropositive conditions?

A

Conditions in which there is auto-antibody production

This is characteritic of many rheumatological conditions

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6
Q

Loss of immune regulation (autoimmune condition) is due to which two factors?

A
  1. Genetic predisposition
  2. Environmental triggers
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7
Q

Anti-CCP antibodies are associated with which condition?

A

Rheumatoid arthritis

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8
Q

Anti-nuclear antibodies are associated with which conditions?

A
  1. SLE
  2. Sjogren’s syndrome
  3. Systemic sclerosis
  4. Mixed connective tissue disease (MCTD)
  5. Autoimmune liver disease
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9
Q

Anti-double stranded DNA antibody (Anti-dsDNA) is associated with which condition?

A

SLE

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10
Q

Anti-Sm antibody is associated with which condition?

A

SLE

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11
Q

Anti-Ro antibody is associated with which conditions?

A
  1. Sjogren’s
  2. SLE
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12
Q

Anti-La antibodies are associated with which condition?

A

Sjogren’s

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13
Q

Anti-centromere antibody is associated with which condition?

A

Systemic sclerosis (limited)

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14
Q

Anti-Scl-70 antibody is associated with which condition?

A

Systemic sclerosis (diffuse)

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15
Q

Anti-RNP antibody is associated with which conditions?

A
  1. SLE
  2. Mixed connective tissue disease
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16
Q

Anti-Jo-1 antibody is associated with which condition?

A

Myositis

17
Q

Anti-phospholipid syndrome is associated with which antibodies?

A
  1. Anti-cardiolipin antibody
  2. Beta-glycoprotein 2
  3. Lupus anticoagulant
18
Q

Small vessel vasculitis is generally associated with which antibody?

A

Anti-neutrophil cytoplasmic antibody (ANCA)

MSK Patrick Stenhouse (60 decks)

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