arthritis

Question 1

__ and __ are cytokines that can trigger infalmmmatory cascades

Answer 1

IL1 and TNF - have ligands for integrins

Question 2

gout caused by…

Answer 2

decreased excretion

Question 3

RA considered a—

Answer 3

erosive arthritis

Question 4

chronic RA includes.. formation

Answer 4

pannus; vascularized erosion?

Question 5

pannus is

Answer 5

membrane of granulation tissue from mesenchyme and bone marrow derived cells

Question 6

ACPA or anti CCP best test and

Answer 6

associate with HLADRB1 and smoking

Question 7

how does MTX work?

Answer 7

its a dihydrofolate reductase inhibitor

Question 8

RA more likely to affect ___ jt than OA

Answer 8

MCP

Question 9

ankylosing spondylitis

Answer 9

HLA B27 gene

exersie NSAIDS and sulfasalazine

Question 10

risk factor SLE

Answer 10

women, African americans, onset when 15-49

Question 11

theory of SLE problem

Answer 11

deficiency in complement pathway that typically breaks down messed up cells

Question 12

serositis

Answer 12

complication of SLE leads to pulm fibrosis and intralveolar hemorrhage

Question 13

SLE

Answer 13

NSAID< hydroxycholorquine, prednisone methotrexate

Question 14

___ can work for steroid resistant SLE but can cause kidney damage

Answer 14

cyclosporine