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Exercise Referral > Arthritic Drugs > Flashcards

Arthritic Drugs Flashcards

1
Q

NSAIDS

A

Ibuprofen
Naproxen
Diclofenic

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2
Q

COX-2 inhibitors

A

Celecoxib

Etoricoxib

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3
Q

When are nsaids and cox-2 inhibitors used?

A

Majority of arthritic conditions via pain, stiffness and inflammation

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4
Q

How do nsaid and cox-2 inhibitors work?

A

Reduce pain, swelling, stiffness and inflammation

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5
Q

What are side effects of nsaids?

A

GI upset

Internal bleeding

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6
Q

What are side effects of cox-2 inhibitors?

A

Possible links to increase risk of MI and stroke

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7
Q

What other medicine will NSAID users usually also have and why?

A

Proton pump inhibitor (ppi) to reduce amount of acid in stomach, to reduce damaging the stomach lining

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8
Q

What does DMARDS stand for?

A

Disease modifying anti-rheumatic drugs

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9
Q

What do DMARDS do?

A

Ease symptoms and slow down progression RA.

Block antibodies chemicals that cause damage to bones, tendons, ligaments and cartilage.

Minimises joint damage, reduce disability and RA impact on ADLs

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10
Q

What is the first drug usually given for RA and the common side effects with it?

A

Methotrexate

Side effects:
Diarrhoea
Mouth ulcers
Hair loss/thinning
Rashes on skin

Sometimes:
Patients blood count and liver

Less common:
Shortness of breath or persistent cough

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11
Q

What are the conventional DMARDS?

A 
Ciclosporin
Cyclophosphamide
Good injections
Hydrochloroquine
Leflunomide
Methotrexate
Mycophenolate
Sulfasalazine
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12
Q

When are DMARDS and biological therapies used?

A

Primarily rheumatoid arthritis to reduce inflammation in joints and relieve pain arthritic conditions

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13
Q

Side effects of DMARDS?

A
  • GI upset
  • sickness
  • Diarrhoea
  • Mouth Ulcers
  • Hair loss
  • Rashes
  • Dampen immune System
  • SOB
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14
Q

Exercise considerations of DMARDS and Biological therapies?

A
  • increased risk of infections
  • Dizziness
  • Loss of balance
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15
Q

How do biological therapies work?

A
  • target individual molecules and stop chemicals in the blood from activating the immune system to attack joint linings
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16
Q

What drugs are biological therapies?

A

Abatacept
Rituximab
Tocilzumab

17
Q

Side effects of Biological Therapies?

A
  • sore throat
  • Fever
  • wheeziness
  • Bruises
18
Q

What drugs are painkillers?

A

Paracetamol
Opioids
Co-codamol

19
Q

When are pain killers used?

A
  • reduction of pain and to control symptoms of arthritis

- all arthritic conditions

20
Q

How do painkillers work?

A
  • relieve pain and symptoms

- interfere with nerve messages sent to brain via spinal cord

21
Q

Side effects of painkillers?

A

Nausea and vomiting

22
Q

Exercise considerations of painkillers?

A
  • drowsiness
  • postural hypotension
  • bradycardia
  • tachycardia
23
Q

Name of corticosteroids?

A

Prednisolone

24
Q

When are corticosteroids used?

A
  • reduce inflammation and suppress condition

- all severe arthritic conditions

25
Q

How do corticosteroids work?

A
  • reduce pain, swelling and stiffness via injection or oral tablet
  • short term usage due to levels of side effects of prolonged
26
Q

Side effects of corticosteroids?

A
  • weight gain
  • osteoporosis
  • bruising
  • facial flushing
  • changes to menstrual cycle
  • mood swings
27
Q

Exercise considerations of corticosteroids?

A
  • muscle weakness
  • weight gain
  • high impact activity as bone thins
  • possible increase in bs/bp
28
Q

What drugs are TCAs?

A

Amitriptyline

29
Q

When are TCAs used?

A
  • long term pain and spinal problems
  • chronic lower back pain
  • fibromyalgia
30
Q

How do TCAs work?

A
  • reduce pain by balancing chemicals in the CNS

- relaxes muscles and improves sleep by blocking pain

31
Q

Side effects of TCAs?

A
  • dry mouth
  • constipation
  • drowsiness
  • blurred vision
  • nausea
32
Q

Exercise considerations of TCAs?

A
  • poor balance
  • hypotension
  • poor body image
  • dizziness
  • slowed reactions

Exercise Referral (2 decks)

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