Arterial Disease of the Limbs Flashcards
What are the five pulses you can feel below the waist and where would you find them?
Aorta (above umbilicus, use two hands to feel for pulsation vs expansion)
Common femoral (mid-inguinal point)
Popliteal (popliteal fossa)
Posterior tibial pulse (next to medial malleolus)
Dorsalis pedis - between first two metatarsals of foot.
What is the main cause of chronic limb ischaemia?
Atherosclerotic disease of arteries supplying the lower limb.
What are some rare causes of CLI?
Vasculitis - swelling of BVs, caused by leukocyte migration.
Burger’s disease - BVs become inflamed and swell and can be blocked with thrombi.
What are the risk factors for developing atherosclerotic disease?
Male, age, smoking, hypercholesterolaemia, hypertension and diabetes.
How are the symptoms of CLI related to the level of arterial blockage?
The more blocked the arteries the worse the symptoms will be.
What is the Fontaine classification?
Used to mark severity of symptoms of CLI.
What are the four stages of Fontaine classification?
1 - asymptomatic, incomplete BV obstruction
2 - mild claudication
2A - claudication when walking more than 200m
2B - claudication when walking less than 200m
3 - rest pain, mostly in feet
4 - necrosis, and/or gangrene of limb
What kinds of question would you need to ask about claudication?
Exercise tolerance, effect of incline, change over time, relieved by rest? Where in leg, type of pain.
What should you ask about rest pain?
Type of pain and relieving factors.
What kinds of question would you need to ask about tissue loss?
Duration, history of trauma, peripheral sensation.
What signs would you look for in chronic limb ischaemia on the lower limbs?
Ulceration, pallor and hair loss.
What things would you examine in the feet?
Capillary refill times, temperature, pulses, peripheral sensation (esp. in diabetics).
What is a doppler?
Machine that uses US to determine blood flow through arteries and veins.
Where would you use the hand held doppler?
Dorsalis pedis and posterior tibial pulses.
What is the ankle brachial pressure index?
ankle pressure/brachial pressure
Can determine clinical status and relates to the symptoms felt by the patient.
How do the symptoms worsen in CLI?
Goes from symptom free, to intermittent claudication, rest pain and then to gangrene and ulceration.
What special test might you want to carry out if you suspect CLI?
Buerger’s test
How do you perform Buerger’s test?
Raise leg and if pallor before 20 degrees elevation then severe ischaemia.
Hang feet over edge of bed, see if slow to regain colour or if go dark red colour (hyperaemic sunset foot).
What causes hyperaemic sunset foot?
Because in CLI autregulation is lost and all the capillaries are open (normally a third are open).
How should patients with PVD be managed?
The same as those with CHD.
What is the best medical therapy in CLI?
Antiplatelet - reduces risk of requiring revascularisation as well as reducing cardiovascular and all-cause mortality.
Statin - inhibits platelet activation and thrombosis, endothelial inflammation activation and plaque rupture.
BP control - target is less than 140/85.
Smoking cessation - excess risk of CV disease diminishes within 4-6 yrs.
Exercise - 150% improvement in walking time.
Diabetic control - 10% of PAD patients are undiagnosed diabetics. Tight glycaemic control prevents microvascular disease.
How would you treat mild/moderate CLI?
BMT only.
How would you treat moderate/severe CLI?
BMT
Angioplasty/stent, surgical bypass.
How would you treat severe/critical CLI?
BMT, angioplasty/stent, endovascular reconstruction, surgical bypass/stent.