Aromatic Synthetic Routes Flashcards

1
Q

Benzene —> Bromobenzene

A

Br2 / FeBr3

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2
Q

Benzene —> Phenyl ketone

A

RCOCl / AlCl3, reflux, anhydrous conditions

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3
Q

Benzene —> Chlorobenzene

A

Cl2 / FeCl3

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4
Q

Benzene —> Nitrobenzene

A

Conc. HNO3 / conc H2SO4, 50C

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5
Q

Benzene —> Alkylbenzene

A

RCl / AlCl3, room temp

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6
Q

Phenyl ketone —> Phenyl alcohol

A

Reduction
NaBH4 / H2O

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7
Q

Phenol —> Sodium phenoxide

A

Neutralisation
NaOH

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8
Q

Phenol —> 2 or 4-nitrophenol

A

dil. HNO3, room temp

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9
Q

Phenol —> 2,4,6-trinitrophenol

A

conc. HNO3

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10
Q

Phenol —> 2,4,6-tribromophenol

A

3Br2

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11
Q

Nitrobenzene —> 3-bromonitrobenzene

A

Br2 / FeBr3

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12
Q

Nitrobenzene —> Phenylamine

A

Reduction
1. conc. HCl / Sn, reflux, 100C

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13
Q

Phenylamine —> 2,4,6-tribromophylamine

A

3Br2

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