Aromatic Synthetic Routes Flashcards
1
Q
Benzene —> Bromobenzene
A
Br2 / FeBr3
2
Q
Benzene —> Phenyl ketone
A
RCOCl / AlCl3, reflux, anhydrous conditions
3
Q
Benzene —> Chlorobenzene
A
Cl2 / FeCl3
4
Q
Benzene —> Nitrobenzene
A
Conc. HNO3 / conc H2SO4, 50C
5
Q
Benzene —> Alkylbenzene
A
RCl / AlCl3, room temp
6
Q
Phenyl ketone —> Phenyl alcohol
A
Reduction
NaBH4 / H2O
7
Q
Phenol —> Sodium phenoxide
A
Neutralisation
NaOH
8
Q
Phenol —> 2 or 4-nitrophenol
A
dil. HNO3, room temp
9
Q
Phenol —> 2,4,6-trinitrophenol
A
conc. HNO3
10
Q
Phenol —> 2,4,6-tribromophenol
A
3Br2
11
Q
Nitrobenzene —> 3-bromonitrobenzene
A
Br2 / FeBr3
12
Q
Nitrobenzene —> Phenylamine
A
Reduction
1. conc. HCl / Sn, reflux, 100C
13
Q
Phenylamine —> 2,4,6-tribromophylamine
A
3Br2