Aromatic Synthesis Routes Flashcards
1
Q
Benzene to Nitrobenzene
Reactants and Conditions
Mechanism
A
Under 55 degrees
Conc. HNO3 Conc. H2SO4
Nitration/Electrophilic Substitution
2
Q
Equation to produce NO2+
A
HNO3 + H2SO4 => NO2 + HSO4 + H2O
3
Q
Nitro Benzene to Phenylamine
Reactants and Conditions
Mechanism
A
Step 1. HCl + Sn
Reflux
Step 2. NaOH
Reduction
4
Q
Benzene to Phenylketone
Reactants and Conditions
Mechanism
A
Acyl Chloride
AlCL3 catalyst
reflux, non aqueous
Acylation Electrophilic Substitution
5
Q
Phenylamine to N-phenylamide
Reactants and Conditions
Mechanism
A
Acyl Chloride
25 degrees
Nucleophilic Addition-elimination
6
Q
Acyl Chloride and AlCl3 equation
A
RCOCL + AlCl3 => RCO+ + AlCl4-