Aromatic Synthesis Routes Flashcards

1
Q

Benzene to Nitrobenzene

Reactants and Conditions
Mechanism

A

Under 55 degrees
Conc. HNO3 Conc. H2SO4
Nitration/Electrophilic Substitution

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2
Q

Equation to produce NO2+

A

HNO3 + H2SO4 => NO2 + HSO4 + H2O

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3
Q

Nitro Benzene to Phenylamine

Reactants and Conditions
Mechanism

A

Step 1. HCl + Sn
Reflux
Step 2. NaOH
Reduction

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4
Q

Benzene to Phenylketone

Reactants and Conditions
Mechanism

A

Acyl Chloride
AlCL3 catalyst
reflux, non aqueous
Acylation Electrophilic Substitution

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5
Q

Phenylamine to N-phenylamide

Reactants and Conditions
Mechanism

A

Acyl Chloride
25 degrees
Nucleophilic Addition-elimination

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6
Q

Acyl Chloride and AlCl3 equation

A

RCOCL + AlCl3 => RCO+ + AlCl4-

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