ARBs

Question 1

ARB indications

Answer 1

HTN 
- Equal to ACE
Nephropathy 
- Equal to ACE
Heart Failure
- If ACE intolerant 
CAD
- If ACE intolerant 
Post MI
- If ACE intolerant

Question 2

ARB adverse reactions

Answer 2

Few/Well Tolerated

• Hypotension
• NVD
• Headache
• DIzziness
• Hyperkalemia
• Peripheral Edema
• Rash
• Cough and angioedema
  &raquo_space;> MUCH LESS THAN ACE

Question 3

ACE in pregnancy

Answer 3

not recommended

Question 4

Notes on ARBs

Answer 4

• Less effect in AA
• Blocks action of angiotensin II
• ARBs have diuretic effect and increase hyperkalemia

ARBs can cause renal failure with renal stenosis or 1 kidney because reduce renal blood flow bc angiotensin blocked and arterioles dilate and further reduce blood flow