AprilBehavioral Flashcards
Most prevelant DSM problems
Anxiety/depression, chemical dependency, somatization, personality disorders
disorders in DSM - IV
297
Axis II Disorders - Clusters A,B,C
Weird, Wild, Worried
Folstein Mental Exam Score of 15 indicates cognition that is, A) Normal B)Mildly Impaired C)Moderate D) Severe
C) Moderate
Folstein Mental Exam Score of 24 indicates cognition that is, A) Normal B)Mildly Impaired C)Moderate D) Severe
B)Mild
4 Depression Screening Tools
Hamilton Rating Scale (Ham-D), Patient Health Questionaire (PHQ-9), Geriatric Depression Scale (GDS), Beck Depression Inventory
2 Anxiety Screening Tools
Hamilton Rating Scale (Ham-A), Patient Health Questionaire (GAD-7)
3 ADHD Screening Tools
SNAP-IV (90), Vanderbilt Teacher (47), Vanderbilt Parent (35)
Truthfullness, Degree of Accuracy of Predictive Statements, Does it test what it says it does
Validity
Consistency of predictive statements, can be reproduced
Reliability
Intelligence Tests
Binet, Stanford-Binet
IQ equation
MA/CA X 100 = IQ
Average IQ range
90-109
Assess ability to recall and draw complicated picture
Rey Complex Figure
MMPI
find psychopathological patterns that may not be apparent
Personality Assessment Inventory
334 items, 4 point likert scale
Mental Retardation associated with
Rubella, low SES, Cytomegalic Inclusion Body Disease, Syphilis, Toxoplasmosis, etc.
2 major cause of mental retardation
FAS and Down Syndrome
Fetal Alcohol Syndrome signs
Small, small eyes, smooth philthrum, small chin, poor coordination, hyperactive, LD, MR, sleep disturbances
Downs signs
Flat head, little tone, flat face, slanty eyes, short nose, wide space fingers - toes, single palmar crease
3 Types of Downs Syndrome
1) Full Trisomy 21 2) Mosaicism 3)Translocation 21 and 15
Prenatal Test for Downs
Aminocentesis - look for HCG
Secondary Problems of MR
low self esteem, neg. self image, psychiatric disorders
Autism prevelance
11/1000
Characterstics of Autism
1)lack of relatedness 2)no social smile 3)babbling, clickin 4)expressive not receptive 5)exploratory play absent 6)rigid play pattern 7) insomnia
Asperbergers
1)solitary 2)impaired social interaction 3)impaired non-verbal communication 4)odd speech
Which is not aspect of Asperberger’s speech A) stilted and repetitive B)obsessive with patterns, weather etc. C)Lack common sense D)Clicking E)Lucid speech
D)Clicking
Rare disorder only affects females with normal development to 6-18 months then regression
Rett Syndrome
Rare form of Autism, onset 3-4 years, loss of motor, language, social skills
Childhood Disintegrative Disorder
4 Types of child abuse
Physical, Sexual, Emotional, Neglect
Suspected child abuse requires verbal and written report within this time frame.
72 hours
Predictors of Perpetration a)victimized B)observed mother brutalized C)male D)adverse childhood experiences
A, B, D
3 types of symptoms of ADHD
Inattention, Hyperactivity, Impulsivity
NT in ADHD, #, firing rate, receptor #
Less, Low rate firing, fewer receptors
Arousal too high, can’t detect between salient and stimuli
Hyperarousal
ADHD remission time
12-20 years
Ist line treatment for ADHD
stimulants, ritalin, adderal, amphetamines
2nd line treatment for ADHD
Strattera and Bupropion
Block Dopamine Uptake
Ritalin,concerat, focalin
Increase Dopamine in synapse
Adderal, Dexadrine, Vyvanse
Inhibit NET, DAT, SERT
Strattera and bupropion
Stimlant adjunct for ADHD
Catapres/Clonidine or Tenex/Guanfacine
Narcolepsy med, can be used for ADHD
Modanfil/Provigil
Procrastionation, low frustration tolerance, sense of flair and low self esteem all Sx of what?
Adult ADHD
Identity status based on presence or absence of these 2 factors
Crisis and Commitment
SCOFF
Sick because full, lost Control, lost One stone, believe to be Fat, Food dominates
Predisposition toward disorder
Diathesis
Diasthesis-Stress Model
Predisposition + stress - protective factors/resilience = disease expression
Is anorexia or bulimia more common?
Bulimics outnumber anorexics 2:1
Eating disorder common to single white college students
Bulimia
Common complication of Bulimia
Dental erosion, esophagus rupture, aspiration pneumontis, arrythmias
Important screen for suspected bulimia
Low potassium
Pharmacological treatment for Bulimia
Antidepressants- TCA, MAO, Prozac
Physical Symptom unique to Anorexia
Amenorrhea
Immature, Need to be in control, Perfectionism, Neg. self view all common to what disorder?
Anorexia Nervosa
Clinical signs of Anorexia Nervosa
Hypothermia, cyanosis, bradycardia, hypotension, low WBC, prolonged QT
Common anorexia complications
Refeeding syndrome, lanugo, hair loss, infertility, pancytopenia
Treament for Anorexia includes A) Antidepressants B) Assess suicide risk C) Inv., family and cognitive therapy D) Correct Deficiencies
B,C,D
Mental Disorders most likely to have addiction disorders A. Bipolar I B. Anxiety C.Schizophrenia D. Antisocial Personality Disorder
D. Antisocial personality disorder
Drugs that mimic mental illness
Cocaine/Meth, Stimulants, LAS, Alcohol, PCP
Diagnose Substance Abuse Disorders if A) Symptoms where there before B) Symptoms persist during abstinence C) Close relative has SUD D)Symptoms began when SUD began
A, B
Why is treating a mental disorder important for a person with SUD?
It increases the chances of overcoming SUD
Pharmacotherapy for SUD
Methadone + Sertraline or benodiazepines
Dysfunction of Scizophrenia
Reward dysfunction (DA)
Danger of treating Schizophrenic for SUD.
Could tip them into a full blown episode
5 axes of DSM IV
1-diagnosis2-permanent psychological problems3-medical conditions4-stressors5-global assessment of functioning
disruptive mood dysregulation disorder
a new diagnosis of temper outbursts in children
attenuated psychosis syndrome
a new prodrome of psychoses
use disorder
new term for addiction
neurocognitive disorder
new term for dementia
paraphilias
group of psychosexual disorders
4 memory tests
rey figure
rey auditory (15 words)
CA verbal learning test
wechsler IX memory scale
2 neuropsychological tests
halstead-reitanluria-nebraska
rorschach test
personality test with 10 inkblots
thematic apperception test (murray)
personalitypicture-what happened?
MMPI test
most comprehensive and best personality.
szondi test
bullshit personality which picture do you relate to?
Scores of MMSE/Folstein
30 points possible23 points is cutoff
scores of wechsler intelligence scale
normed to 100 70 = 2 sds from 100= mental retardation
3 Intelligence tests used with kids
mccarthy scale BEST PRESCHOOL
wechsler preschool/primary
Bayley for infants
cultural-familial retardation
no organic brain damage
Normal distribution of IQ<70
amniocentesis (4) for down’s
alpha fetoprotein (low)HCGestriol (low)inhibin A
advanced language in autism
expressive language
gene with autistic assoc
HOXA1
onset of childhood schizophrenia
AFTER 5 years
childhood disintegrative disorder, CDDtype of disease2 symptoms
severe, later-onset autismloss of language, bowel, bladder
identity and intimacy development of males, females
males identity first, then intimacy
females develop at the same time<
2 high yield questions to screen eating disorders
are you satisfied with your eating patterns?do you ever eat in secret?
anorexiafemale-male ratiomean year onset
10:117 years
2 types bulimia
<p>purging typenonpurging type</p>
bulimia female-male ratio
weight
8:1
average weight
russell’s sign
callouses on dorsum of hand from self-induced vomiting.
bulimia prognosis NOT affected by (2)
age of onset
duration of symptoms
two types anorexia
restricting
binge eating/purging
refeeding syndrome
<p>low electrolytes in response to anorexia. life threatening</p>
pancytopenia
low RBC’s, WBC’s in response to anorexia
female athlete’s triad (3)
disordered eating
amenorrhea
osteoporosis
2 disorders in ADHD
executive functionself-regulation
3 parts of PF cortex with ADHD associations
dorsolateral - attention
PF motor - motor activity
orbital - impulsivity
orbital PF cortex to ganglia and back (name of circuit)
impulsivity circuit
function dorsal anterior cingulate, ACC
motivation
tx for hyperarousal (2)(more common with adults Include MOA
amoxetine - NE inhibitor
guanfancin - alpha 2A adrenergic receptor agonist
2 types stimulants for ADHD
methylphenidate
amphetamine
3 brand names methylphenidate
ritalin
concerta
focalin
mechanism methylphenidate (stimulant)
DA reuptake inhibitor
3 brand names amphetamine
Adderall
Dexedrine
Vyvanse
MOA of amphetamine
increases presynaptic release of DA
brand name atomoxetine
Strattera
MOA and benefit atomoxetine
NE reuptake inhibitor first then DA, then 5HT
takes time but low abuse potential
MOA of Buproprion
NDRI
3rd line for ADHD
TCA antidepressants
4th line tx ADHD (2)
Clonidine Guanfacine
MOA Clonidine, Guanfacine
alpha 2A adrenergic receptor agonist
Guanfacine has fewer side effects
Clonidine decreases BP
CV contraindications for stimulants (3)
congentical heart defects
arrhythmias
syncope
if you have substance use patient, the odds that they have a psychiatric disorder
50%
patient with depression
how many have SUD?unipolar?bipolar?
unipolar 30%
odds bipolar 60%
schizophrenia & borderline antisocial personality disorder% SUD
50%
85%
PCP and ketamine abuse cause what type of symptoms
antisocial behaviors
therapy type which is particularly useful for bipolar
group therapy
SCID
assessment tool for personality disorders
structured clinical interview
“W” words describing cluster A-C personality disorders
weird
wild
worried
3 descriptors for cluster A
accusatory
aloof
awkward
2 descriptors for cluster B
big emotions
bad to the bone
3 descriptors for cluster C
cowardly
compulsive
clingy
3 cluster A disorders
paranoid
schizoid
schizotypal
2 treatments for cluster A disorders
social skills training
Haloperidol
summary of schizoid PD
distant (negative symptoms)
summary of schizotypal PD
magical thinking(positive symptoms)
4 cluster B disorders
antisocial
borderline
histrionic
narcissistic
2 characteristics borderline
unstable
suicidality
2 characteristics histrionic
attention seeking
sexually seductive
3 cluster C disorders
avoidant
dependent
obsessive-compulsive PD
2 tx for avoidant personality
social skills training
Sertraline
3 strong beliefs of OCD personality disorder
order
perfectionism
control
4 stages sexual cycle
desire
arousal
excitement
orgasm/resolution
dyspareunia
genital pain during sex
2 sexual desire disorders
hypoactive sexual desire
sexual aversion
female sexual arousal disorder a reduction of (2)
lubrication
swelling
vaginisumus
involuntary muscle spasm of vaginal control
4 steps of PLISSIT model of sex therapy
permission
limited information
specific suggestions
intensive therapy
difference
viagra
levitra
cialis
4 hour duration
12 hour duration
2+ day duration
Alprostadil
used for penile injections, transurethral
Bremelanotide
malanocortin agonist not yet on market
aphrodisiac
3 treatments for SRI induced sexual problems
besides dose reduction and switching agents
augment with Buproprion cyproheptadine (antihistamine)
weekend drug holiday (but not Fluoxetine)
2 interventions to reduce alcohol demand for adolescents
life skills training
motivational interviewing
4 types schizophrenia
paranoid
disorganized
catatonic
undifferentiated
3 perinatal infections ++schizohrenia
toxoplasmosis
influenza
borrelia
2 birth months of ++schizo
feb/march
expressed emotion theory
increased shouting, etc in families- ++schizo
3 NTs (and amts) implicated in schizophrenia
+DA
+5HT
-glutamate
anosognosia
poor insight found in schizophrenics(lack of awareness of disability)
schizophreniform disorder
<6 months
schizoaffective disorder
w/mono or bipolar depression
gold standard of schizo drugsand negative component
Clozapine
agranulocytosis
unique components of Risperidone
part typical, part atypical
two atypicals with less weight gain
ziprasidone
ariprazole
hysteriabriquet’s syndrome aka
somatization disorder
somatization prevalence (incl gender)onset
2% women 0.2% men
adolescent onset.
duration = year
5 diagnostic criteria somatization
onset < 30 years 4 different sites pain 2 GI1 sexual pseudo-neuro
conversion disorder
age of onset
kids to 35
couvade
male pregnancy, a conversion disorder
comptocormia
flexion of spine, a conversion disorder
body dysmorphic disorder
preoccupation with a real or imagine defect of body
hypochondriasis
prevalence
gender
4-9% of population
males=females
difference between malingering and factitious
malingering = external motivations factitious = for medical tx
disorder associates with factitious
borderline
peregrinating factitious disorder
munchausen
profile of munchausen patient
single male
40’santisocial
treatment model for conduct disorder
include unacceptable treatment
multisystemic family therapy
NOT GROUP THERAPY
2 comorbidities of conduct disorder
SUD
ADHD
2 treatments ODD
positive parenting program
problem-solving communication training
3 internalizing disorders (adolescent)
anxiety/depression
OCD
phobias
3 externalizing disorders (adolescent)
conduct disorder
ODD
ADHD
CRAFFT questions for adolescents SUD
car? relax? alone? family friends? forget? trouble?
3 depression screenings for kids
PHQ-9
beck depression inventory
children’s depression inventory
tx for adolescent depression
include unacceptable
SSRIs
TCAs are contraindicated - toxic + prolongs QT interval
5 pediatric antidepressants with FDA approval
4 SSRI
1 exceptional TCA
fluoxetine, sertraline, fluvoxamine, escitalopram
clomipramine
black box warning for pediatric antidepressants
Include follow up schedule
suicide risk
follow up:weekly-1 month,biweekly - 1 month,then quarterly
length of time for adolescent antidepressant treatment
6-9 months
prevalence suicide
12/100,000
3 uniqe risk factors for adolescents and suicide
exposure
triggers
past attempts
% of suicides with a diagnosis
include most common
90%
mood disorders
4 high yield suicide screening questions
do you have suicidal thoughts?plan?means?past attempt?
double depression
major depression and dysthymia
treatment course for depression
9 months - 1 year
neurotransmitters reduced in depression (3)include increased receptor
LOW levels of 5HT, NE, DA+5HT2 binding sites
frequency of episodes for SAD
2 years, 2 episodes
prevalence SAD
1-4%
2 tx SAD
10,000 lux for 30 minutes/day
SSRIs
MOA Venlafaxine
SNRI
MOA Buproprion
DNRI
1st line tx for depression (3 but 1 is a class)
SSRIs
Venlafaxine
Buproprion
2nd line tx depression
Duloxetine
MOA Duloxetine
SNRI
3rd line tx depression (2)
TCA
Mirtazapine
4th line tx. depression
MAO inhibitor
prevalence of bipolar disorder
<p><1% (.6%)</p>
bipolar 1 vs. bipolar 2
bipolar 1 - 1 week manic + 3 symptoms
bipolar 2 - hypomanic (perceived as positive)
genetics of bipolar
weak correlation;
1st degree relatives 10% assoc.
2nd degree relatives 5% assoc
occam’s razor
use as few dx as possible to explain all symptoms
personality disorders often confused with bipolar
cluster B
only 2 agents proven to have anti-suicidal effects
Clozapinelithium
activation syndrome
a manic-like syndrome caused by anti-depressants.NOT MANIA!
tx for impulsivity and emotional liability in bipolar disorder
Olanzapine (zyprexa)or other anti-psychotics
proposed phenotype system of DSM V for bipolar (4 levels)
narrow phenotype
phenotype 1
phenotype 2
broad phenotype
% of SUD patients that have a mental disorder
50%
2 substances that can cause antisocial behaviors
ketamine
PCP
therapy better than meds? for bipolar
group therapy
pharm therapies for anxiety disorders
SSRIs
two decent SSRIs for anxiety and SUD
Paroxetine
Sertraline (PTSD)
<p>1st line treatment for GAD (with or without SUD)
</p>
Buspirone
yerkes-dodson curve
performance v anxiety
base rate
rate found depends where you found it (psych wards, etc)
female/male ratio of panic disorder AND agoraphobia
4:01
2 qualities for diagnosis OCD
impairment
patient recognizes unreasonableness
3 requirements for PTSD diagnosis
re-experience
avoidance
hyper-vigilance
2 components of behavioral model of anxiety
2 factor learning theory
neutral stimulus avoidance behavior
positively reinforced
3 regions of brain overactive in panic disorder
amygdala
temporal cortex
hippocampus
2 regions of brain overactive in OCD
caudate
orbital gyrus
best treatment for OCD
behavioral therapy
Buspirone MOA
partial 5HT agonist
diagnosing SUD in adolescents
2 or more of (4)
(4 things that cause probs)
SOLS (save our leaky ship) obligations hazardous legal social