Approach to Acute SOB Flashcards
Life threatening differentials
- PE
- Pneumothorax
- Asthma / COPD
- Pneumonia
- Acute LVF
- ACS
Focussed hx
Explore
- When did it start?
- How did it come on?
- Exercise tolerance - current vs normal
- Orthopnoea, PND
Systems review
- general - fever
- chest - chest pain, wheeze, cough, sputum, leg swelling
PMH
- Happened before
- Other medical conditions
- Asthma / COPD - baseline and severity (home nebs/O2), exacerbation hx and how mx, normal peak flow
- recent surgery
DH + Allergies - incl inhaler compliance
SH - smoking, alcohol, long-haul travel
Focussed exam
Tracheal deviation and JVP Inspect chest Expansion, apex, heaves Percuss Auscultate heart and lungs Legs - swelling, tender, oedema Peak flow if asthmatic
Investigations
Bloods
- FBC, U&E, CRP
- D-dimer (if Wells score low)
- BNP
- Blood cultures
- ABG
Orifice
- sputum culture
X-ray / imaging
- CXR
- CTPA
ECG
Pulmonary embolism
- hx
- exam findings
- ix findings
- mx
Hx
- pleuritic chest pain
- haemoptysis and SOB
- RF - long haul flight, surgery, immobility
Exam
- Tachycardia, raised JVP, RV heave
- Tachypnoea, clear chest / pleural rub
- Calves - DVT
- Massive PE - SBP<90, pulseless, persistent bradycardia
Ix findings
- D-dimer raised - if Wells score low
- CTPA (diagnostic)
- ECG - tachy, RV strain (t wave inversion in right chest and inferior leads), RBBB, RAD, S1Q3T3 (rare)
- ABG - hypoxaemia and hypocapnia
- CXR - may show wedge opacity, effusion
Mx
- treatment-dose anticoagulation
- thrombolysis if massive PE
Pneumonia
- hx
- exam findings
- ix findings
- mx
Hx
- fever
- SOB
- Productive cough
- Pleuritic chest pain
- Confusion
Exam
- Tachypnoea, cyanosis
- Coarse creps, bronchial breathing
- dullness to percussion
- increased vocal resonance
Ix
- CXR (diagnostic) - consolidation, air bronchogram
- Raised CRP
- Cause - sputum and blood culture, mycoplasma serology, urinary pneumococcal and legionella antigens
Mx
- O2
- Abx
Pneumothorax
- hx
- exam findings
- ix findings
- mx
Hx
- Sudden onset pleuritic chest pain
- SOB if large enough
- RF - Marfans, COPD/asthma
Exam
- Reduced chest expansion
- Absent breath sounds
- Hyperresonance
- Tension - tracheal deviation, hypotension, raised JVP, resp distress
Ix
- CXR (diagnostic) - air in pleural space
Primary Mx
- <2cm - CXR monitoring
- > 2cm or Sx - aspirate
Secondary
- <1cm - observe for 24 hours + high flow oxygen
- 1-2cm - aspirate
- 2cm - chest drain
Asthma exacerbation
- hx
- exam findings
- ix findings
- mx
Hx
- SOB, wheeze, known asthmatic
Exam
- Tachypnoea, wheeze, use of accessory muscles
- reduced air entry and PEFR
Ix - clinical dx
- CXR - exclude infection and pneumothorax
- ABG - usually normal PaO2 and low PaCO2 (hyperventilation) - severe if hypoxia and hypercapnic
- Blood and sputum cultures if ?infection
Mx
- salbutamol and ipratropium nebs
- steroids
- magnesium IV
- abx if infection
COPD exacerbation
- hx
- exam findings
- ix findings
- mx
Hx
- SOB, wheeze, change in sputum, known COPD/lifelong smoker
Exam
- tachypnoea, reduced air entry, wheeze, accessory muscles
Ix
- CXR (exclude infection and pneumothorax)
- ABG (hypoxaemia and hypercapnia)
Mx
- salbutamol and ipratropium nebs
- steroids
- abx
- BiPAP if required
Other resp differentials
Extrinsic allergic alveolitis Laryngitis Bronchitis Pneumonitis Bronchiectasis LRTI Pleural effusion
ACS
- hx
- exam findings
- ix findings
- mx
Hx
- crushing central chest pain
- radiates to left arm or neck
- nausea, SOB, sweaty
- CVD RF
Exam
- sweaty, SOB, pain
- signs of HF, Brady or tachy
Ix
- ECG - ST elevation, new LBBB, inverted T waves, Q waves
- Troponin - increased (normal in UAP)
- CXR - normal / signs of heart failure
- Coronary angiography
Mx - MONA
- Morphine
- Oxygen
- Nitrates
- Anti-platelets
- PCI
Acute LVF
- hx
- exam findings
- ix findings
- mx
Hx
- SOB, orthopnoea, PND
- pink frothy sputum
- peripheral oedema
- cardiac hx
Exam
- tachycardia, tachypnoea
- raised JVP
- fine bibasal creps
- S3
- peripheral oedema
Ix
- CXR (A-E)
- ECHO (diagnostic)
- BNP
- ECG - look for MI
Mx - POD MAN
- Position sitting up
- Oxygen
- Diuretics
- Morphine
- Antiemetic
- Nitrate infusion
- CPAP if required
- treat cause
Other cardiac differentials
Cardiomyopathy Myocarditis Acute valvular disease Pericardial effusion Pulmonary hypertension
Hyperventilation of anxiety
- hx
- exam findings
- ix findings
- mx
Hx
- tight chest pain, SOB, sweating, dizzy, palpitations, feeling of impending doom
- anxious personality / other sx of GAD
- recurrent episodes triggered by stimulus
Exam
- usually normal, hyperventilation
Ix - diagnosis of exclusion
- ECG and troponin - exclude MI
- D-dimer - exclude PE
- CXR - exclude infection
- ABG - resp alkalosis
Mx
- reassurance
- CBT
- SSRI
Other differentials
DKA Overdose Metabolic acidosis Sepsis Foreign body Anaphylaxis Anaemia