Appendicitis Flashcards
Define Appendicitis
Appendicitis refers to inflammation of the appendix
What is the key symptom patients present with?
Acute Abdominal pain
At what age is there peak incidence of appendicitis
20-40 year olds
Why is appendicitis uncommon in the extremes of age?
The young have a relatively wide appendiceal lumen
Whilst in the elderly the appendix is almost entirely obliterated
Is there higher prevalence of appendicitis in:
a) Males
b) Females
a) Males
Where in the bowel does the appendix open
Opens onto the caecum of the large bowel
The majority of appendix are in which position
Retrocaecal
What supplies the appendix
Appendix is supplied by the appendiceal mesentery, which hangs from the terminal ileum and contains the appendiceal branch of the ileocolic artery (from the superior mesenteric artery)
What are the taeniae coli
Three longitudinal muscles that run the length of the large intestine
Name some of the causes of luminal obstruction of the appendix
- Faecolith [most common cause] i.e. hard collections of stool that form and block the lumen
- Lymphoid hyperplasia
- Caecal tumour
Describe the pathophysiology of appendicitis
- Typically caused by an obstruction of the lumen of the appendix i.e., the point where the appendix meets the caecum
- Obstruction can result in the trapping of pathogens within the appendix. The stasis can result in bacteria overgrowth leading to infection and inflammation
- Reduced venous drainage and inflammation can result in increased pressure within the appendix.
- As the pressure rises further, the arterial supply to the appendix becomes compromised leading to ischaemia, which in turn can cause perforation of the appendix
- When the appendix ruptures, faecal contents and infective material are released into the peritoneal cavity causing peritonitis i.e. inflammation of the peritoneal lining
Name some of the risk factors for appendicitis
- Age
- Peak incidence in 20-40 year olds
- Uncommon in the extremes of age i.e. young children and >50 because the young have a relatively wide appendiceal lumen, whilst in the elderly, it is almost entirely obliterated
- Peak incidence in 20-40 year olds
- Sex – Higher male prevalence
- Family history
- Ethnicity – more common in Caucasians
Describe the abdominal pain associated with appendicitis
Dull central pain that progresses and becomes a sharp pain that moves and becomes localised to the right iliac fossa
Name some of the symptoms of appendicitis
- Abdominal pain – key symptom
- Nausea and vomiting
- Loss of appetite
- Low grade fever
- Weight loss
- Constipation
Define the term “rebound tenderness”
Pain upon removal of pressure of the palpitation rather than application of pressure to the abdomen