Apoptosis Flashcards
1
Q
What are the two types of death signals
A
- Internal
- external
2
Q
How is an external death signal activated
A
external death signal molecules bind to surface receptor protein —> triggers protein cascade
3
Q
How is an internal death signal activated
A
Internal death signal results from damage to DNA causing activation of p53 tumour suppressor protein
4
Q
What causes destruction of cell in both cell death signals
A
Activation of capsases (protease enzyme)
5
Q
Why is apoptosis essential during development
A
It removes cells that are no longer required
6
Q
What could be a result of an absence of growth factors
A
Cells may initiate apoptosis
