Apoproteins

Question 1

Cofactor role: Apo C-II

Answer 1

Activates lipoprotein lipase

Question 2

Cofactor role: Apo-AI

Answer 2

Activates ACAT

Question 3

Ligand role: Apo E

Answer 3

Binds to LRP/remnant receptor

Question 4

Ligand role: Apo B-100

Answer 4

Binds to LDL receptor

Question 5

Ligand role: Apo-AI

Answer 5

Binds to HDL receptor

Question 6

Structural role: Apo B-48

Answer 6

Chylomicrons

Question 7

Structural role: Apo B-100

Answer 7

VLDL, LDL

Question 8

Structural role: Apo A-I

Answer 8

HDL

Question 9

What do chylomicrons transport?

Answer 9

Dietary TAGs and cholesterol

Question 10

What does lipoprotein lipase do?

Answer 10

Converts TAGs to free fatty acids and glycerol

Question 11

What do VLDLs transport?

Answer 11

Endogenous TAGs and cholesterol

Question 12

___ have more protein than lipid. ___ have much more lipid than protein.

Answer 12

HDL; Chylomicron

Question 13

Chylomicrons transport dietary TAG to ___.

Answer 13

Adipose/other tissues

Question 14

Chylomicron remnants deliver remaining dietary TAG to ___.

Answer 14

Liver

Question 15

VLDL transport endogenous TAG to ___.

Answer 15

Adipose tissue/skeletal and heart muscle

Question 16

IDL-VLDL remnant delivers remaining TAG and cholesterol to the ___.

Answer 16

Liver

Question 17

LDL delivers cholesterol to the ___.

Answer 17

Liver

Question 18

HDL accepts cholesterol from peripheral cells, esterifies it, and transports the CEs to the ___.

Answer 18

Liver