Apex Unit 8 Regional Flashcards

1
Q

Order the spinal ligaments from superficial to deep. ​

(1 is superficial, and 4 is deep)

A

Interspinous ligament ​ + ​ 1

Ligamentum flavum ​ + ​ 2

Posterior longitudinal ligament ​ + ​ 3

Anterior longitudinal ligament ​ + ​ 4

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2
Q

Which statements about the epidural space are true? ​ (Select 2.)

It neighbors the pia mater.
It ends at the sacrococcygeal ligament.
Batson’s plexus passes through the lateral region.
Its volume is increased in the third stage of pregnancy.

A

It ends at the sacrococcygeal ligament

Batson’s plexus passes through the lateral region

The epidural space neighbors the dura (not the pia) mater, and it terminates at the sacrococcygeal ligament.

Any condition that increases intra-abdominal pressure (obesity, pregnancy, etc.), puts backpressure on the epidural veins. This increases the volume of blood contained within, thereby reducing (not increasing) the volume of the epidural space.

Batson’s plexus is the network of epidural veins that drain the spinal cord and the meninges. It typically passes through the lateral and anterior regions of the epidural space.

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3
Q

In the adult, which anatomic structure correlates with the termination of the dural sac?

Superior iliac spines
Tuffier’s line
L1 vertebra
Sacral cornua

A

Superior iliac spines

Know these landmarks:

Conus medullaris = L1
Tuffier’s line = L4-L5 interspace ​ (correlates with the iliac crests)
Dural sac ends =S2 ​ (correlates with the superior iliac spines)
Sacral hiatus and sacrococcygeal ligament = S5

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4
Q

Transection of the C6 posterior nerve root will cause:

motor deficit of the middle finger.

impaired sympathetic outflow to the C6 distribution.

sensory block of the thumb.

diaphragmatic paralysis.

A

Sensory block of the thumb

Transection of the C6 posterior nerve root will cause a sensory block in the ipsilateral thumb.

The best way to approach this question is to think of the modalities carried by the anterior and posterior nerve roots. Remember that the posterior roots are sensory and the anterior roots are motor and autonomic. Knowing this would’ve helped you eliminate all the other answer choices! If you didn’t know this, you’d have to know about the dermatomes and their distributions. And yes, you’ll need to know these for the NCE!

Diaphragmatic paralysis occurs with injury to C3-5. We injured the C6 sensory nerve root, so this answer was wrong for two reasons.

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5
Q

Match each nerve fiber type with its degree of myelination.

A

A alpha ​ + ​ Heavy
A gamma ​ + ​ Moderate
B ​ + ​ Light
C ​ + ​ None

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6
Q

How does neuraxial anesthesia affect respiratory mechanics?

Impaired inspiration
Impaired expiration
Impaired inspiration and expiration
No impairment

A

Impaired inspiration and expiration

Accessory muscle function is reduced by neuraxial blockade.

Impairment of the intercostal muscles (inspiration and expiration) as well as the abdominal muscles (ability to cough and clear secretions) will decrease pulmonary reserve. This is particularly important for the patient with severe COPD.

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7
Q

What factor is an absolute contraindication to spinal anesthesia?

Multiple sclerosis
Patient refusal
Peripheral neuropathy of lower extremity
Mitral stenosis

A

Patient refusal

This is the kind of question that should ruffle your feathers a bit. When confronted with several “right” answers, you need to learn how to select the answer that is most correct.

Patient refusal is always an absolute contraindication to neuraxial anesthesia.

The other answer choices are relative contraindications to neuraxial anesthesia. The textbooks offer conflicting guidelines in these areas, but they agree that the decision to proceed with a neuraxial technique should be made on a case-by-case basis.

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8
Q

Identify the MOST appropriate techniques for a subarachnoid block in a patient scheduled for hemorrhoidectomy. ​ (Select 2.)

Lidocaine 5% in 7.5% dextrose and the sitting position
Bupivacaine 0.3% in water and the jackknife position
Tetracaine 0.2% in water and the sitting position
Procaine 10% in water and the jackknife position

A

Lidocaine 5 percent in 7.5 percent dextrose and the sitting position

Bupivacaine 0.3 percent in water and the jackknife position

There are two ways to approach this patient. We can use a hyperbaric solution (lidocaine 5 percent in 7.5 percent dextrose) and place the block in the sitting position or we can use a hypobaric solution (bupivacaine 0.3 percent in water) and place the block in the jackknife position.

Why are the other answers wrong?

If we chose a hyperbaric solution (procaine 10 percent in water) and the jackknife position, the local anesthetic will concentrate in the lumbar region.
If we chose a hypobaric solution (tetracaine 0.2 ​ percent in water) and the sitting position, the local anesthetic will rise in a cephalad direction, failing to adequately anesthetize the sacral nerve roots.

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9
Q

A 22-pound child requires a caudal anesthetic. How many milliliters of 0.2% ropivacaine should be administered to achieve a T10 sensory blockade? ​

(Round your answer to the nearest whole number)

A

10
For a T10 sensory block, you need to administer 1 mL/kg. Here’s how to perform the calculation:

Convert pounds to kilograms: ​ 22 lbs / 2.2 kg = 10 kg
Multiply the patient’s weight by the formula: ​ 10 kg x 1 mL/kg = 10 mL

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10
Q

When compared to intrathecal fentanyl, which findings are MORE likely with intrathecal morphine? ​ (Select 3.)

Late respiratory depression
Sympathectomy
Faster onset
Wider band of analgesia
Increased risk of nausea
Higher plasma concentration
A

Wider band of analgesia
Late respiratory depression
Increased risk of nausea

The correct answers describe a drug that is more hydrophilic. When we compare the two drugs in the question, we should recognize that morphine is more hydrophilic than fentanyl. Therefore, morphine causes late respiratory depression, will provide a wider band of analgesia, and increases the risk of nausea.

The wrong answers describe a drug that is more lipophilic. Lipophilic drugs tend to have a faster onset and achieve a higher plasma concentration. ​ ​

Neuraxial opioids do not cause sympathectomy. This was a bit of trick, because neither fentanyl nor morphine cause sympathetic denervation.

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11
Q

Identify the MOST common side effect of neuraxial opioid administration.

Pruritus
Respiratory depression
Urinary retention
Nausea and vomiting

A

Pruritus

When it comes to the side effects of neuraxial opioids, you must know the big four:

Pruritus (most common)
Respiration depression
Urinary retention
Nausea and vomiting

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12
Q

Which factors increase the risk of postdural puncture headache? ​ (Select 3.)

Old age
Needle perpendicular to long axis of meninges
Early ambulation
Air for loss of resistance during epidural placement
Continuous spinal catheter
Pitkin needle

A

Pitkin needle

Needle perpendicular to long axis of meninges

Air for loss of resistance during epidural placement

The risk of PDPH is increased by the type of needle (cutting tip is worse than pencil point tip) and needle orientation (perpendicular is worse than parallel).

Using air or saline for epidural placement does not affect the risk of incurring a dural puncture, however if this complication was to occur, then injecting air into the CSF will create a pneumocephalus and increase the risk of PDPH.

Things that don’t increase the risk of PDPH include: early ambulation, old age, and use of a continuous spinal catheter.

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13
Q

You are called to remove an epidural catheter from a patient receiving enoxaparin for DVT prophylaxis. According to the Consensus Statement from the American Society for Regional Anesthesia and Pain Medicine, what is the MOST appropriate course of action?

Hold enoxaparin for six hours, pull catheter, then restart enoxaparin one hour later.

Hold enoxaparin for 12 hours, pull catheter, then restart enoxaparin two hours later.

Hold enoxaparin for 24 hours, pull catheter, then restart enoxaparin six hours later.

Order a hematology consult.

A

Hold enoxaparin for 12 hours, pull catheter, then restart enoxaparin two hours later

The risk of epidural hematoma is similar during block placement and catheter removal, therefore you must know the ASRA guidelines for both circumstances.

The most appropriate action is to hold enoxaparin for 12 hours, pull the catheter, then restart enoxaparin two hours later.
If you know these guidelines, you won’t need to consult.

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14
Q

Following the resolution of a subarachnoid block, the patient complains of severe pain in the buttocks that radiates through her legs. She has normal motor function. What should be said to the patient?

Most patients will experience pain for one month.
Ibuprofen will help your pain.
Avoid bupivacaine if you have another spinal anesthetic in the future.
This was due to the use of a micro spinal catheter.

A

Ibuprofen will help your pain

This patient is experiencing transient neurologic symptoms. This type of pain will respond to NSAIDs, opioids, and trigger point injections.

Why are the other answers wrong?

TNS typically persists for 1 - 7 days (not a month).
Lidocaine is the most common cause of TNS (not bupivacaine).
Micro spinal catheters increase the risk of cauda equina syndrome (not TNS).

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15
Q

Beginning at the nerve roots, order the components of the brachial plexus from medial to lateral.

(1 is most medial, and 4 is most lateral)

A

Trunks ​ + ​ 1
Divisions ​ + ​ 2
Cords ​ + ​ 3
Branches ​ + ​ 4

The brachial plexus has 5 components. Beginning at the spinal cord and working outward: ​ roots, trunks, divisions, cords, and branches.

Mnemonic: ​ Reach To Drink Cold Beer

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16
Q

Thirty minutes after an interscalene block, the patient complains of dyspnea. His SpO2 is 93 percent on 40 percent FiO2 via facemask. He is otherwise stable. What is the BEST intervention at this time?

Midazolam
Noninvasive positive pressure ventilation.
Verbal reassurance
Chest x-ray

A

Chest x-ray

There are two causes of respiratory distress in this patient that should immediately come to mind: ​ phrenic nerve blockade and pneumothorax.

The phrenic nerve is blocked nearly 100 percent of the time with an interscalene approach to the brachial plexus. This is usually only an issue in the patient with a reduced pulmonary reserve - think COPD.
The cupola of the lung is just medial to the first rib - it’s higher on the right side, and it is at risk of needle puncture during the interscalene or supraclavicular approach to the brachial plexus. A chest x-ray should be ordered to rule out pneumothorax in this patient.
Why are the other answers wrong?

Noninvasive positive pressure ventilation is useful if the patient can’t compensate for phrenic nerve paralysis. Positive pressure of any kind can convert a pneumothorax to a tension pneumothorax.
Midazolam might further impair this patient’s respiratory distress. In some contexts, it may be useful if the patient is overly anxious. Either way, it’s not the best answer here.
Verbal reassurance is appropriate, but it does not treat the cause of respiratory distress.

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17
Q

Select the BEST landmark for a supraclavicular block using a nerve stimulation technique.

First rib
Divisions of brachial plexus
Pectoralis major
Subclavian artery

A

Subclavian artery

Of the answer choices provided, the subclavian artery is the best landmark for a supraclavicular block using a nerve stimulation technique.

Why are the other answers wrong?

Although the supraclavicular is a trunks/divisions level block, this structure is not a landmark.
The pectoralis major is an important structure for the infraclavicular approach.
You can’t see the first rib, so it’s not a landmark.

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18
Q

Which artery is MOST likely to be injected with local anesthetic during supraclavicular block placement?

Axillary
Vertebral
Subclavian
Carotid

A

Subclavian

If you know the landmarks and surrounding anatomy for each nerve block, you’ll be able to reason out the associated complications.

Interscalene block = vertebral artery
Supraclavicular block = subclavian artery
Infraclavicular block = subclavian artery or axillary artery (depends on block level)

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19
Q

During an infraclavicular block using a nerve simulator technique, which patient response indicates proper needle placement?

Finger flexion

Arm abduction

Elbow flexion

Arm adduction

A

Finger flexion

​Acceptable motor responses include finger flexion/extension when nerve stimulation is decreased from 1 mA to 0.5 mA. ​

Why are the other answers wrong?

The axillary nerve exits the sheath at a variable level, so it may be stimulated outside of the sheath. If you observe a deltoid response, withdraw the needle to the skin and redirect superiorly.
The musculocutaneous nerve also exits the sheath at a variable level, so it may be stimulated outside of the sheath. If you observe a biceps response, withdraw the needle to the skin and redirect caudally.
The needle must transverse the pectoralis major and minor before reaching the brachial plexus. Pectoralis stimulation means the needle is too shallow, and you should continue advancing the needle.

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20
Q

When compared to the supraclavicular approach to the brachial plexus, the infraclavicular approach has a higher risk of: ​ (Select 2.)

respiratory compromise.
patient discomfort.
intravascular injection.
pneumothorax.

A

Patient discomfort

Intravascular injection

The supraclavicular approach has a higher risk of pneumothorax and phrenic nerve inhibition. Either can potentially cause respiratory compromise.

The infraclavicular approach has a higher risk of intravascular injection and patient discomfort (piercing the pec major and minor with the needle).

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21
Q

Which region is MOST likely to be inadequately anesthetized following an axillary block with a transarterial technique?

Lateral forearm
First digit
Medial forearm
Fifth digit

A

Lateral forearm

The musculocutaneous n. usually exits the brachial plexus proximal to the location of this block. Therefore, this nerve must be blocked separately (in the coracobrachialis muscle).

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22
Q

In the patient who receives intravenous regional anesthesia for a carpel tunnel release, what is the MINIMUM amount of time that the tourniquet must remain inflated following injection of the local anesthetic?

(Enter your answer in minutes)

A

20 minutes

Toxicity is the most significant risk of the Bier block.
The tourniquet must remain inflated for a minimum of 20 minutes following local anesthetic injection. This allows enough time for the LA to absorb into the tissue. If the cuff is deflated too soon (or if it fails), then the local anesthetic is washed into the systemic circulation where it can produce seizures or cardiovascular collapse.

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23
Q

Which nerves arise from the lumbar plexus? ​ (Select 3.)

Posterior femoral cutaneous
Femoral
Lateral femoral cutaneous
Obturator
Pudendal
Sciatic
A

Femoral
Obturator
Lateral femoral cutaneous

The lumbar plexus arises from the anterior (ventral) rami of L1-L4. It gives rise to 6 nerves:

Iliohypogastric
Ilioinguinal
Genitofemoral
Lateral femoral cutaneous
Obturator
Femoral
​
The sacral plexus gives rise to the sciatic and posterior femoral cutaneous nerves.

The coccygeal plexus gives rise to the pudendal nerve.

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24
Q

Match each nerve with its corresponding nerve roots.

A

Lateral femoral cutaneous ​ + ​ L2-L3
Femoral ​ + ​ L2-L4
Sciatic ​ + ​ L4-S3
Posterior femoral cutaneous ​ + ​ S1-S3

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25
Q

The psoas compartment block anesthetizes all of the following nerves EXCEPT the:

obturator.
sciatic.
lateral femoral cutaneous.
saphenous.

A

Sciatic
This one was a bit tricky, but it emphasizes the point that you need to understand how the nerves divide after leaving the plexus.

The lumbar plexus gives rise to three key nerves for lower extremity anesthesia:

Lateral femoral cutaneous
Obturator
Femoral
​
Although the femoral nerve wasn't an answer choice, you know that the saphenous nerve is a division of the femoral nerve. Anesthesia of the femoral nerve will also anesthetize the saphenous nerve.

The sciatic nerve comes from the sacral plexus. This plexus is not anesthetized by the posterior approach to the lumbar plexus (psoas compartment block).

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26
Q

Pick the statements that BEST describe the proper technique for performing a fascia iliaca compartment block. ​ (Select 2.)
Local anesthetic should be deposited between the fascia iliaca and fascia lata.
Ultrasound is required.
Local anesthetic is deposited anterior to the iliopsoas muscle.

Two pops should be felt before injecting local anesthetic.

A

Two pops should be felt before injecting local anesthetic

Local anesthetic is deposited anterior to the iliopsoas muscle

This block is easily performed with landmarks and feel; a nerve stimulator or ultrasound aren’t required.

You should feel two pops as you insert the needle. These are felt as the needle penetrates the fascia lata and then the fascia iliaca.

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27
Q

Which peripheral nerve block can be combined with a sciatic nerve block to enhance tolerance of a lower leg tourniquet?

Posterior tibial
Sural
Saphenous
Common peroneal

A

Saphenous

The combination of a sciatic (or popliteal) and saphenous block provides complete anesthesia to the lower leg, ankle, and foot. Therefore, if a patient has a sciatic nerve block, then anesthetizing the saphenous nerve would enhance tolerance of a lower leg tourniquet. Recall that the saphenous nerve is a continuation of the posterior branch of the femoral nerve.

Increasing tolerance of an upper leg tourniquet would require a sciatic nerve block and a psoas compartment block or a 3-in-1 block (femoral, obturator, lateral femoral cutaneous).

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28
Q

The sciatic nerve provides motor innervation to the: ​ (Select 2.)

biceps femoris.
quadriceps.
sartorius.
semitendinosus.

A

Biceps femoris
Semitendinosus

Know that the sciatic innervates the biceps femoris, semitendinosus, and semimembranosus muscles. ​

29
Q

Stimulation of the tibial nerve in the popliteal fossa causes:

plantar flexion and inversion of the foot.
plantar flexion and eversion of the foot.
dorsiflexion and inversion of the foot.
dorsiflexion and eversion of the foot.

A

Plantar flexion and inversion of the foot

This is an important concept for answering questions about:

The expected responses during a popliteal nerve block.
Peripheral nerve injury.

30
Q

Match each nerve block with the region that it anesthetizes.

A

Tibial nerve ​ + ​ Heel
Sural nerve ​ + ​ Lateral aspect of foot
Superficial peroneal nerve ​ + ​ Dorsum of foot
Deep peroneal nerve ​ + ​ Web space between 1st and 2nd toe

31
Q

Injecting a ring of local anesthetic from the midpoint of the distal tibia toward the inferior border of the medial malleolus will most likely anesthetize the:

tibial nerve.
saphenous nerve.
superficial peroneal nerve.
sural nerve.

A

Saphenous nerve

It’s critical that you understand how and where to block the five nerves in the ankle.

Injecting a ring of local anesthetic from the midpoint of the distal tibia toward the inferior border of the medial malleolus will anesthetize the saphenous nerve.

32
Q

Match each structure with its relationship to the epidural space.

A

Anterior border ​ + ​ Posterior longitudinal ligament

Lateral border ​ + ​ Vertebral pedicles

Posterior border ​ + ​ Ligamentum flavum and vertebral lamina

Caudal border ​ + ​ Sacrococcygeal ligament

Cranial border ​ + ​ Foramen magnum ​ (not asked in question)

33
Q

Identify the structures that the needle encounters during a subarachnoid block via the midline approach. ​ (Select 3.)

Posterior longitudinal ligament
Arachnoid mater
Dura mater
Pia mater
Interspinous ligament
Anterior longitudinal ligament
A

Interspinous ligament
Dura
Arachnoid

You must know the structures through which the needle passes during an epidural or subarachnoid block:

Epidural block:
Skin → subcutaneous tissue → subcutaneous fat → supraspinous ligament → interspinous ligament → ligamentum flavum → epidural space

Subarachnoid block:

All of the structures for an epidural → dura mater → subdural space → arachnoid mater → subarachnoid space

Although the subdural space is not a true space, a potential space can be created by a bleeding vessel or ​ injecting local anesthetic between the dura and arachnoid.

34
Q

What is the first ligament that the needle encounters while performing a subarachnoid block via the paramedian approach?

Posterior longitudinal ligament
Supraspinous ligament
Interspinous ligament
Ligamentum flavum

A

Ligamentum flavum

The paramedian approach to the subarachnoid space is useful when there is significant calcification of the interspinous ligament.

The needle is directed approximately 15 degrees off the sagittal plane. From here, the needle is inserted 1 cm lateral and 1 cm below to the caudal edge of the vertebral spinous process directly above the interspace.

Because the needle is inserted off of the midline, it does not encounter the supraspinous and interspinous ligaments. The ligamentum flavum is the first and only ligament that the needle encounters during the paramedian approach.

The layers encountered during the paramedian approach from superficial to deep: ​

Skin → subcutaneous tissue → ligamentum flavum → dura mater → subdural space → arachnoid mater → subarachnoid space

35
Q

To avoid spinal cord trauma in the infant, what is the HIGHEST interspace that the spinal needle can safely be inserted?

T12
L2
L4
S1

A

L4

Here’s a quick recap of the anatomy of the distal spinal cord. Know the differences between the adult and the infant.

Spinal cord → Conus medullaris (tip of spinal cord) → Cauda equina & Internal filum terminale → Dural sac ​ → External filum terminale

When placing the needle in the subarachnoid space, you want the tip to enter below the conus medullaris and above the lower border of the intrathecal space (dural sac).

In the Adult:
The spinal cord ends at L1/ L2.
The dural sac ends at S2.
​In the Infant:

The spinal cord ends at L3.
The dural sac ends at S3.

If the conus medullaris in the infant resides at L3, then you don’t want to insert the needle any higher than the L4 interspace.

Although there is some conflicting evidence in the literature, we want you to know the anatomic landmarks on this page.

36
Q

Which factors have the GREATEST influence on the spread of local anesthetic in the intrathecal space? ​ (Select 2.)

Volume
Concentration
Baricity
Dose

A

Dose
Baricity

Be able to answer variations of this question for spinal as well as epidural anesthesia. The best way to think about this is to break it down into drug factors, patient factors, and procedure factors.

Most Important Factors That Determine Spinal Block Height:

Drug Factors = dose, baricity
Patient Factors = CSF volume, pregnancy, old age
Procedure Factors = patient position

Other Factors That Determine Spinal Block Height:

Drug Factors = volume, concentration, temperature, viscosity
Patient Factors = height, weight, intraabdominal pressure
Procedure Factors = needle type, needle orifice orientation, level of injection
Factors That Do Not Determine Spinal Block Height:

Vasoconstrictors
Gender

37
Q

Which factors have the GREATEST influence on the spread of local anesthetic in the epidural space? ​ (Select 3.)

Patient position
Needle orifice orientation
Volume
Pregnancy
Concentration
Dose
A

Volume
Dose
Pregnancy

Be able to answer variations of this question for spinal as well as epidural anesthesia. The best way to think about this is to break it down into drug factors, patient factors, and procedure factors.

Most Important Factors that Determine Epidural Block Height:
Drug Factors = volume, dose
Patient Factors = pregnancy, old age
Procedure Factors = level of injection

​Less Important Factors that Determine Epidural Block Height:

Drug Factors = concentration
Patient Factors = weight, height, relative pressure in body cavities
Procedure Factors = patient position
The following factors are not important at all: ​ LA additives, speed of injection, and needle orifice orientation.

38
Q

When injected into the intrathecal space, which opioids undergo the GREATEST degree of rostral spread? ​ (Select 2.)

Sufentanil
Fentanyl
Hydromorphone
Morphine

A

Morphine
Hydromorphone

Neuraxial opioids inhibit neurotransmitter release (substance P) in substantia gelatinosa (Rexed lamina II) in the dorsal horn of the spinal cord.

The relative lipophilicity of an opioid determines its tendency to stay inside the intrathecal space vs. its tendency to diffuse into the systemic circulation.

More hydrophilic opioids:
Examples: ​ morphine, hydromorphone
They do not easily diffuse across biologic membranes, so they tend to remain inside the intrathecal space.
Because of this, they spread to higher levels. This is called rostral spread.
They produce a wider band of analgesia.
More lipophilic opioids:

Examples: ​ sufentanil, fentanyl
They diffuse into the blood stream faster, so they do not spread as high as less lipophilic agents.
They produce a narrower band of analgesia.

39
Q

Which nerve roots are the MOST resistant to the effects of local anesthetics? ​ (Select 2.)

L3
L5
S1
S3

A

L5
S1

A few key points about L5 and S1:
They are the largest spinal nerves.
They are the most resistant to the effects of local anesthetics.
The L5-S1 interspace is the largest interspace in the vertebral column.

40
Q

In what order does regression of spinal anesthesia occur?

(1 recovers first and 4 recovers last)

A

1 ​ + ​ Motor function
2 ​ + ​ Touch
3 ​ + ​ Pinprick
4 ​ + ​ Temperature

To assess the adequacy of your spinal anesthetic, you need to know a thing or two about differential blockade. Spinal nerves are anesthetized in the following order:

​Pre-ganglionic sympathetic
Temperature
Pin prick (fast pain)
Touch
Motor
​
Spinal nerves recover in the opposite order in which they were anesthetized.
Motor
Touch
Pinprick (fast pain)
Temperature
Pre-ganglionic sympathetic
41
Q

A patient with severe COPD received a spinal anesthetic. Impairment of which of the following muscles is MOST likely to contribute to respiratory compromise? ​ (Select 2.)

Intercostals
Sternomastoid
Abdominal
Diaphragm

A

Intercostals
Abdominal

Neuraxial anesthesia impairs accessory muscle function; vital capacity and expiratory respiratory volume are decreased.

Patients with good reserve usually tolerate these changes well, although they may still complain of dyspnea. This is usually the result of proprioceptive blockade of the intercostal and abdominal muscles. If ventilation is adequate, these patients may require verbal reassurance.

Patients with severe respiratory disease may not tolerate the effects of neuraxial anesthesia. Impairment of the intercostal muscles (inspiration and expiration) as well as the abdominal muscles (ability to cough and clear secretions) can reduce pulmonary reserve.
The diaphragm is innervated by the phrenic nerve. Recall that C3-5 keeps the diaphragm alive, so unless the anesthetic reaches an excessively high level, spinal anesthesia does not affect the diaphragm or the phrenic nerve.

Apnea is usually the result of hypoperfusion of the respiratory center in the brainstem. Apnea is generally NOT due to phrenic nerve paralysis (unless there is C3-5 blockade). Indeed, breathing usually resumes when cardiac output and arterial blood pressure are restored with vasopressors and intravascular volume expansion.

42
Q

A reduction in which of the following is the primary mechanism for hypotension after a T4 spinal anesthetic?

Preload
Afterload
Heart rate
Contractility

A

Preload

By anesthetizing pre-ganglionic sympathetic B fibers, spinal anesthesia reduces sympathetic tone. This is called sympathectomy.

Cardiac SNS innervation ​ = ​ T1 - T4
Vascular SNS innervation ​ = ​ T1 - L2

It’s important to understand that sympathectomy with spinal anesthesia can be as high as 2 - 6 levels above the level of sensory blockade! By contrast, sympathectomy is the same as the sensory level during epidural anesthesia.

Cardiovascular consequences of sympathectomy include:

↓ Preload ​ (venodilation)
↓ Stroke volume ​ (↓ preload)
↓ Afterload ​ (arterial dilation)
↓ Heart rate (↓ cardiac accelerator function ​ & ↓ preload)

Because 75% of the blood volume resides in the venous circulation, dilation of the venous capacitance vessels (↓ preload) is the primary mechanism of hypotension with a high spinal.

The body compensates with vasoconstriction above the level of sympathectomy, however a higher block limits the effectiveness of this compensatory mechanism.

43
Q

Identify the MOST appropriate location to place the epidural catheter for each surgical procedure.

A

Thoracotomy ​ + ​ T4
Whipple procedure ​ + ​ T6
Radical prostatectomy ​ + ​ T8
Total hip arthroplasty ​ + ​ L2

Placing the epidural catheter in the region of the incisional dermatome provides the best analgesia with the lowest risk of side effects. Simply put, we can give less drug.

Where to place the catheter based on the location of the incision:

Thoracic ​ = ​ T4-T8
Upper abdominal ​ = ​ T6-T8
Middle abdominal ​ = ​ T7-T10
Lower abdominal ​ = ​ T8-T11
Lower extremity ​ = ​ L1-L4
44
Q

After placement of an epidural, a patient complains of a fronto-occipital headache, diplopia, and tinnitus. What is the BEST intervention to treat this patient’s symptoms?

Diazepam
Caffeine
Sumatriptan
Fentanyl

A

Caffeine

This patient is experiencing a post-dural puncture headache. The best way to prevent PDPH is to avoid puncturing the dura, although smaller needles and pencil-point tip needles reduce the risk as well.

Common s/sx include: ​ fronto-occipital headache, diplopia, tinnitus, and N/V. Symptoms usually improve when the patient lays flat.

When a hole is created in the dura, CSF leaks through it. This reduces CSF volume and pressure. Traction on the meninges and cerebral vasodilation cause the headache.
Conservative treatment measures include:

Intravenous hydration ​ (increases CSF production)
Supine position ​ (maintains a higher CSF pressure in the brain)
Caffeine ​ (reverses cerebral vasodilation)
Theophylline ​ (reverses cerebral vasodilation)
NSAIDs

Sumatriptan has not been shown to reliably relieve PDPH.

The definitive treatment is an epidural blood patch.

45
Q

Injection during an epidural blood patch should stop when the patient:

senses pain in her buttocks.
experiences lower extremity weakness.
receives 20 mL of blood.
notes pressure in her back.

A

Notes pressure in her back

With a success rate > 90 percent, the epidural blood patch is the definitive treatment for PDPH. ​ If the technique fails, it may be repeated a second time after 24 hours. The second attempt also carries a > 90 percent success rate.

Using sterile technique, 10 - 20 mL of venous blood is withdrawn from the patient and then reintroduced into the epidural space. You should stop injecting when the patient senses pressure in her legs, buttocks, or back.

A blood patch is useful for two reasons. First, it compresses the epidural and subarachnoid spaces, which increases CSF pressure. Second, it acts as a plug that prevents further leakage.

A prophylactic blood patch is not effective in preventing PDPH.

46
Q

What is the MOST common consequence of an epidural blood patch?

Sepsis
Cranial nerve palsy
Backache
Bradycardia

A

Backache

Backache and radicular pain are the most common side effects of an epidural blood patch. Treatment consists of NSAIDs and antispasmodic medications.

Less common side effects include cranial nerve palsies and transient bradycardia.

47
Q

When compared to an epidural technique, which of the following complications are more likely with spinal anesthesia? ​ (Select 2.)

Meningitis

Epidural abscess

Cauda equina syndrome

Spinal hematoma

A

Meningitis
Cauda equina syndrome

Complications more likely to occur after spinal anesthesia include:

Meningitis ​ (direct contamination of CSF)
Cauda equina syndrome ​ (high LA concentrations may be neurotoxic)

Complications more likely to occur after epidural anesthesia include:

Epidural abscess ​ (direct contamination of epidural space)
Spinal hematoma ​ (large needle = larger hole)
Traumatic spinal cord injury ​ (larger needle = larger injury)

48
Q

Select the organism that is MOST likely to cause post-spinal bacterial meningitis.

Haemophilus influenzae
Streptococcus viridans
Streptococcus pneumoniae
Methicillin resistant staphylococcus aureus

A

Streptococcus viridans

When placing a neuraxial block, there are two routes by which an infectious organism can reach the CSF.

Failure of aseptic technique
Bacteria in the patient’s blood at the time of SAB

Streptococcus viridans is one of the most common culprits responsible for post-spinal bacterial meningitis. It is commonly found in the mouth, and this is why it’s so critical to wear a mask while performing a neuraxial block.

49
Q

What is the MOST efficacious skin preparation method for neuraxial anesthesia?

Chlorhexidine + Isopropyl alcohol
Soapy water + Chlorhexidine
Chlorhexidine + Iodine solution
Isopropyl alcohol + Iodine solution

A

Chlorhexidine + Isopropyl alcohol

Suitable methods to prepare the skin for neuraxial anesthesia include chlorhexidine, isopropyl alcohol, and iodine solutions.

According to Miller, the best method is a combination of chlorhexidine + isopropyl alcohol.

Chlorhexidine is neurotoxic, so it’s imperative that you allow it to dry completely before you penetrate the skin with the needle.

50
Q

A patient with an epidural catheter at the L4-5 interspace received 20 mL of 0.25% bupivacaine. After 25 minutes, the patient loses consciousness. What is the MOST likely explanation for this complication?

Systemic toxicity

Transient neurologic symptoms

Subdural injection

Total spinal

A

Subdural injection

A potential space is an area between two membranes. It is usually empty, but it can expand to a much larger size if fluid accumulates between the membranes.

The subdural space is a potential space. It is located between the dura and the arachnoid. It is deep to the epidural space and superficial to the subarachnoid space. Be able to identify all of these spaces in an image.

While the epidural space extends to the foramen magnum, the subdural space extends intracranially. The hallmark of a subdural injection is high but patchy block that usually develops after a 15-30 minute delay. If local anesthetic reaches the brain, unconsciousness can occur. Treatment is supportive.

The key to this question is understanding the time sequence of events. If local anesthetic was injected into the vasculature or intrathecal space, the patient would’ve experienced symptoms within several minutes (not 25).

51
Q

A patient requests an epidural for an open gastric bypass procedure. She continued all of her home medications through the day of surgery. Which of the following preclude the placement of an epidural catheter in this patient? ​ (Select 2.)

Aspirin

Enoxaparin

Clopidogrel

Subcutaneous heparin

A

Enoxaparin
Clopidogrel

The most significant risk factor for epidural hematoma is the presence of a coagulation defect.

​Laboratory cutoffs (these differ from book to book):

Platelets ​ < ​ 100,000/mcL
PT ​ > ​ 2x normal
PTT ​ > ​ 2x normal
Drugs that increase risk of hematoma:

Thienopyridine derivatives (clopidogrel, ticlopidine)
Glycoprotein IIb/IIIa antagonists (abciximab, eptifibatide, tirofiban)
Low molecular weight heparin (enoxaparin, dalteparin, tinzaparin)
Intravenous heparin
Oral anticoagulants (warfarin)

Drugs that do NOT increase the risk of hematoma:

NSAIDs
Mini-dose unfractionated heparin for DVT prophylaxis
Herbal medications (garlic, ginkgo, ginseng)

Note that combinations of these drugs may increase the risk of hematoma formation.

52
Q

Diagnostic features of epidural hematoma include all of the following EXCEPT:

fever.

lower extremity weakness.

radicular pain.

bladder dysfunction.

A

Fever

Bleeding in the spinal canal can compress the spinal cord, impairing its perfusion.

Patients will present with radicular back pain, lower extremity weakness, and bowel and bladder dysfunction.

Suspicion of an epidural hematoma warrants an emergent MRI. Surgical decompression is the definitive treatment, yielding the best results if performed within 8 hours of symptom onset.

As an aside, an epidural abscess is more likely to present with fever and anterior spinal artery syndrome presents as painless lower extremity motor impairment with bowel and bladder dysfunction.

53
Q

A caudal anesthetic is suitable for all of the following procedures EXCEPT:

anal fistula repair.

pilonidal cystectomy.

hemorrhoidectomy.

labor pain relief.

A

Pilonidal cyst

Caudal anesthesia is useful for procedures that require sensory block at or below T10.

Absolute contraindications to caudal anesthesia include spina bifida, meningitis, and meningomyelocele of the sacrum.

Relative contraindications to caudal anesthesia include pilonidal cyst, abnormal landmarks, hydrocephalus, intracranial tumor, and progressive degenerative neuropathy.

54
Q

Which sequence of numbers correlates with the respective number of roots, trunks, divisions, cords, and branches in the brachial plexus?

6, 5, 3, 6, 3
5, 3, 6, 3, 5
5, 3, 4, 6, 5
6, 3, 5, 5, 3

A

5,3,6,3,5

The numbers are palindromic. This may help you remember the sequence a little bit easier.

Roots: C5 -T1
Trunks: Superior, Inferior, Middle
Divisions: 3 anterior and 3 posterior (6 branches)
Cords: Lateral, Posterior, Medial
Terminal branches: Musculocutaneous, Axillary, Radial, Median, Ulnar (MARMU)

55
Q

The lateral and medial cords supply the: ​ (Select 3.)

radial nerve.
musculocutaneous nerve.
circumflex nerve.
axillary nerve.
ulnar nerve.
median nerve.
A

Median nerve
Ulnar never
Musculocutaneous nerve

The lateral and medial cords supply the median, ulnar, and musculocutaneous nerves.

The posterior cord supplies the radial and axillary nerves.

The circumflex nerve is another name for the axillary nerve.

56
Q

Which nerve was spared if the patient complains of sensation in the anterolateral aspect of the forearm following an axillary block?

Musculocutaneous
Medial antebrachial cutaneous
Medial
Radial

A

Musculocutaneous

The musculocutaneous nerve supplies sensation to the anterolateral aspect of the forearm. It can be anesthetized with a field block with 3-5 mL of local anesthetic injected into the coracobrachialis muscle.

The medial antebrachial cutaneous is a branch of the medial nerve that supplies sensation to the medial aspect of the forearm.

The median nerve supplies sensation to the hand.

The radial nerve and its branches supply sensation to the medial aspects of the posterior forearm.

57
Q

A patient complains of sensation at the anterolateral aspect of the forearm. Which block was MOST likely performed?

Interscalene
Supraclavicular
Axillary
Infraclavicular

A

Axillary

The musculocutaneous nerve provides sensation to the anterolateral aspect of the forearm. Since it leaves the sheath at the level of the coracoid process, it is missed during the axillary approach to the brachial plexus.

All of the blocks proximal to the coracoid process capture the musculocutaneous nerve. These include the interscalene, supraclavicular, and infraclavicular approaches to the brachial plexus.

58
Q

Which peripheral nerve block has the HIGHEST incidence of chylothorax?

Infraclavicular
Interscalene
Supraclavicular
Axillary

A

Infraclavicular

The thoracic duct drains into the subclavian vein, and injury to this structure can cause chylothorax (lymph in the chest). There’s a left and a right thoracic duct, but since the left one is much larger, it is more susceptible to injury. ​

Of all of the approaches to the brachial plexus, the infraclavicular approach is associated with the greatest risk for chylothorax. A subclavian line can cause a chylothorax as well (again, this is more likely on the left side).

59
Q

When performing an interscalene block with nerve stimulation, all of the following are acceptable end-points EXCEPT:

trapezius movement.
arm abduction.
forearm flexion.
forearm extension.

A

Trapezius movement

There are two common answers for this question. First, scapula movement from trapezius stimulation results from cervical plexus stimulation. Second, hiccups result from phrenic nerve stimulation. Neither of these are acceptable endpoints for interscalene blockade.

Acceptable twitch responses include:

Arm abduction (deltoid muscle)
Forearm flexion (biceps muscle)
Forearm extension (triceps muscle)
Arm internal rotation (pectoralis major muscle)
60
Q

Where do the cords of the brachial plexus transition into the terminal branches?

First rib
Scalene muscles
Clavicle
Axilla

A

Axilla

The roots convert to trunks at the lateral border of the scalene muscles.

The trunks change over to divisions under the clavicle and over the 1st rib.

The divisions converge into cords as they course under the pectoralis minor muscle.

The cords become the terminal branches beyond the lateral border of the pectoralis minor muscle (in the axilla).

61
Q

Complications of interscalene blockade are more common in patients with: ​ (Select 2.)

epilepsy.
Horner syndrome.
myasthenia gravis.
chronic obstructive pulmonary disease.

A

COPD
Myasthenia gravis

The C3-C5 nerve roots give rise to the phrenic nerve, and blockade of this nerve results in temporary paralysis of the ipsilateral diaphragm.

An interscalene block anesthetizes the phrenic nerve nearly 100 percent of the time.
A supraclavicular block can cause this side effect as well (the incidence is lower).

An impairment of diaphragmatic function must be considered in any patient with decreased pulmonary reserve. Examples include severe COPD, neuromuscular disease (myasthenia gravis), or contralateral lobectomy or pneumonectomy.

Although intravascular injection of local anesthetics can produce seizures, a history of seizures does not preclude the use of regional anesthesia.
We used Horner syndrome as a trigger word. If you didn’t appreciate the context of the question, simply reading “complications” and “Horner syndrome” may have led you down the wrong path. Indeed, Horner syndrome is a known side effect of an interscalene block - not a co-morbidity that increases the risk of complications from this procedure. The take home here is to always understand the essence of what the question asks of you. Word associations aren’t enough.

62
Q

Which regions of the brachial plexus are the primary targets of the supraclavicular approach? ​ (Select 2.)

Trunks
Roots
Divisions
Cords

A

Trunks
Divisions

The interscalene approach targets the roots.

The supraclavicular approach targets the trunks and divisions.

The infraclavicular approach targets the cords.

The axillary approach targets the terminal branches.

63
Q

Which of the following increases the risk of pneumothorax during a supraclavicular block?

Short stature
Performing the block on the right side
Using a 5 cm needle
Morbid obesity

A

Performing the block on the right side

Performing a supraclavicular block on the right side increases the chances of a pneumothorax.

Pneumothorax is the greatest risk for supraclavicular block. Since the cupola of the lung is higher on the right side, it is more likely to be punctured during a supraclavicular block on the right side.

Tall, thin patients have a greater risk for pneumothorax. Suspect pneumothorax if the patient coughs or complains of chest pain.

The use of a 5 cm needle is standard practice.

64
Q

Which autonomic reflex is MOST likely to occur during shoulder surgery in the sitting position with an interscalene block?

Celiac
Bezold-Jarisch
Baroreceptor
Bainbridge

A

Bezold-Jarisch

In the sitting position, blood pools in the lower extremities. This causes a profound reduction in venous return. The Bezold-Jarisch reflex essentially slows an empty heart to allow it adequate time to fill. Afferent signals travel to the vasomotor center by way of unmyelinated vagal C fibers. Clinically it manifests as hypotension, bradycardia, and peripheral vasodilation. It is likely also responsible for cardiovascular collapse during spinal anesthesia. Prophylactic beta blockers may blunt this response.

The Bainbridge reflex or atrial stretch reflex is stimulated by hypervolemia. Increased venous return stimulates atrial stretch receptors and activates the SNS. Clinically this manifests as an increased heart rate, vasodilation, and natriuresis. ​

The celiac reflex is triggered by traction or pressure on structures within the abdominal and thoracic cavity. This reflex is mediated by the vagus nerve and presents as bradycardia, hypotension, and apnea.

​The baroreceptor reflex responds to short-term fluctuations in arterial blood pressure. Hypotension actives the SNS, while hypertension inhibits the SNS.

65
Q

Match each nerve injury with its clinical presentation. ​ ​

A

Ulnar ​ + ​ Claw hand
Median ​ + ​ Inability to oppose the thumb and pink finger
Radial ​ + ​ Wrist drop

Nerve injury can be the result of needle transection, intraneural injection, use of a tourniquet, positioning, and surgery. At a minimum, you should know:

ulnar = claw, ​ median = pinch, ​ radial = wrist

Ulnar nerve injury is the most common neuropathy that occurs during the perioperative period. Over time, muscular atrophy causes the hand to take on a “claw like” appearance.

Median nerve neuropathy impairs the ability to oppose the thumb and pinky finger. This injury is likely to occur during axillary blockade or antecubital IV placement in an anesthetized patient. ​
Radial nerve neuropathy creates wrist drop and loss of sensation to the lateral portion of the palm. This injury usually results from direct compression at the spiral groove of the humerus.

66
Q

What are the MOST common causes of median nerve injury? ​ (Select 2.)

Antecubital IV insertion.
Improper positioning.
Axillary approach to the brachial plexus.
Compression to the postcondylar groove at the humerus.

A

Antecubital IV insertion
Axillary approach to the brachial plexus

Median nerve neuropathy impairs the ability to oppose the thumb and pinky finger. This injury is likely to occur during axillary blockade or antecubital IV placement in an anesthetized patient. ​

As an aside, many, if not most upper extremity nerve injuries originate from unknown causes - not improper positioning.

67
Q

A patient has an axillary block. Blockade of which of the following nerves will enhance an awake patient’s tolerance of an upper arm tourniquet?

Axillary
Intercostobrachial
Median antebrachial cutaneous
Musculocutaneous

A

Intercostobrachial

The intercostobrachial nerve arises from T2. It is not contained in the sheath, so it is not blocked by any of the approaches to the brachial plexus. A field block is usually required to anesthetize this nerve. Blockade of the intercostobrachial nerve helps alleviate discomfort when an upper arm tourniquet is used in the awake patient. ​

68
Q

The sacral plexus gives rise to the:

saphenous nerve.
common peroneal nerve.
obturator nerve.
lateral femoral cutaneous nerve.

A

Common peroneal nerve

The sacral plexus gives rise to the posterior femoral cutaneous and sciatic nerves.

In the leg:
The sciatic divides into the common peroneal and tibial nerves.

In the ankle:
The common peroneal gives rise to the peroneal nerve (superficial and deep) and contributes to the sural nerve.
The tibial nerve gives rise to the posterior tibial nerve and it also contributes to the sural nerve.

The lumbar plexus gives rise to the obturator and femoral nerves, and the saphenous nerve is an extension of the femoral nerve.

69
Q
All of the following nerves are included in a 3-in-1 block EXCEPT the:
posterior femoral cutaneous.
femoral.
lateral femoral cutaneous.
obturator.
A

Posterior femoral cutaneous

The 3-in-1 block is a different approach to a femoral nerve block. It is designed to anesthetize 3 nerves with 1 injection:

Femoral n.
Lateral femoral cutaneous n.
Obturator n. (commonly missed)