Aortic Stenosis Flashcards

1
Q

What is the most common primary heart valve disease?

A

Degenerative calcification

Degenerative calcification is a leading cause of heart valve disease.

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2
Q

What are the two common types of congenital aortic valve disease?

A
  • Bicuspid aortic valve (BAV)
  • Unicuspid aortic valve (very rare)

Bicuspid aortic valve is the most common congenital heart valve malformation.

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3
Q

What is the LV response to increased afterload?

A

LVH

LVH stands for Left Ventricular Hypertrophy, a condition where the muscle wall of the heart’s left ventricle thickens.

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4
Q

What structural abnormality occurs in the aorta due to significant chronic aortic stenosis?

A

Post stenotic dilation

This refers to the dilation that occurs in the aorta above the stenotic valve, often seen in cases of aortic stenosis.

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5
Q

Fill in the blank: The condition characterized by left ventricular hypertrophy is a response to increased _______.

A

afterload

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6
Q

True or False: Post stenotic dilation occurs below the valve in cases of aortic stenosis.

A

False

Post stenotic dilation occurs above the valve (ascending aorta).

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7
Q

Is lvh eccentric or concentric when having LVH from AS

A

Eccentric

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8
Q

What clinical sign can result from low cardiac output?

A

Syncope

Syncope can lead to dizziness and loss of consciousness.

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9
Q

Fill in the blank: _______ is a symptom associated with low cardiac output.

A

Syncope

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10
Q

What are some symptoms associated with syncope?

A
  • Dizziness
  • Loss of consciousness
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11
Q

What does elevated venous filling pressures lead to?

A

Exertional Dyspnea

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12
Q

What type of murmur is associated with cardiac auscultation?

A

Harsh, systolic ejection murmur (crescendo-decrescendo)

This type of murmur is often indicative of aortic stenosis or other conditions affecting blood flow.

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13
Q

What is an early systolic sound commonly found in BAV?

A

Early systolic ‘click’

BAV stands for Bicuspid Aortic Valve, which is a congenital heart defect.

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14
Q

What are the surgical replacement options for symptomatic aortic stenosis (AS)?

A

Surgical Aortic valve replacement (SAVR), Transcatheter aortic valve replacement (TAVR), Balloon valvuloplasty

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15
Q

What does SAVR stand for?

A

Surgical aortic valve replacement

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16
Q

What types of valves can be used in SAVR?

A

Mechanical or porcine (pig) valves

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17
Q

Which surgical replacement option is the most popular?

A

Transcatheter aortic valve replacement (TAVR)

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18
Q

What is Balloon valvuloplasty?

A

A balloon put in the Aortic valve that is a temporary fix for aortic stenosis

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19
Q

Who are the typical candidates for Balloon valvuloplasty?

A

Usually children and elderly who are not candidates for surgical options

20
Q

What is the typical symptoms of Quadracuspid AV?

A

Palpitations, chest pain, dyspnea, syncope

Quadracuspid atrioventricular valve is an uncommon heart defect that rarely presents with stenosis.

21
Q

Quadracuspid AV is almost always associated with which condition?

A

AR (Aortic Regurgitation)

This association highlights the clinical significance of Quadracuspid AV in cardiac assessments.

22
Q

What percentage of all valve replacements for aortic stenosis (AS) are due to Bicuspid Aortic Valve (BAV)?

23
Q

What percentage of all births is affected by Bicuspid Aortic Valve (BAV)?

24
Q

What shape is the opening of a Bicuspid Aortic Valve typically described as?

A

Football shaped

25
Q

What change occurs to the leaflets of a Bicuspid Aortic Valve with aging?

A

Prone to thickening

26
Q

What characteristic is seen in the systolic phase of a Bicuspid Aortic Valve in the PLAX view?

A

Systolic ‘doming’

27
Q

What is the term used to describe the seam in a Bicuspid Aortic Valve?

28
Q

What is a challenge of 2D planimetry in severe cases?

A

severe Ca++ due to shadowing and poor 2D resolution

29
Q

What does Ca++ refer to in this context?

30
Q

True or False: 2D planimetry is always reliable regardless of the severity of the condition.

31
Q

What does AVA stand for?

A

Aortic Valve Area

32
Q

What is the equation for calculating Aortic Valve Area (AVA)?

A

0.785 x LVOT Dia^2 x V1 / V2

33
Q

What are the three measurements needed to calculate AVA?

A
  • LVOT diameter
  • PW Doppler peak velocity at the site of the LVOT diameter (V1)
  • CW peak velocity across the AV (V2)
34
Q

What is V1 in the context of the AVA calculation?

A

PW Doppler peak velocity at the site of the LVOT diameter

35
Q

What does V2 represent in the AVA calculation?

A

CW peak velocity across the AV

36
Q

What is the peak velocity range for mild aortic stenosis?

A

2.6-2.9 m/s

Mild aortic stenosis is characterized by a peak velocity of 2.6-2.9 m/s.

37
Q

What is the mean gradient in mmHg for moderate aortic stenosis?

A

20-40 mmHg

Moderate aortic stenosis has a mean gradient ranging from 20 to 40 mmHg.

38
Q

What is the indexed AVA for severe aortic stenosis?

A

<0.6 cm²/m²

Severe aortic stenosis is defined by an indexed AVA of less than 0.6 cm²/m².

39
Q

What peak velocity defines severe aortic stenosis?

A

≥4.0 m/s

Severe aortic stenosis is indicated by a peak velocity of 4.0 m/s or greater.

40
Q

Fill in the blank: The mean gradient for severe aortic stenosis is _______ mmHg.

A

≥40 mmHg

Severe aortic stenosis is indicated by a mean gradient of 40 mmHg or more.

41
Q

What is the AVA for moderate aortic stenosis?

A

1.0-1.5 cm²

Moderate aortic stenosis is defined by an AVA between 1.0 and 1.5 cm².

42
Q

What is the mandatory probe for AS?

A

PEDOF Probe

PEDOF stands for Pulsed Echo Doppler Flow Velocity Meter, which is used for assessing aortic stenosis.

43
Q

What type of probe is the PEDOF probe?

A

Blind probe

A blind probe does not provide imaging capabilities.

44
Q

What is the frequency of the PEDOF probe?

A

225 Hz

This frequency is used for Doppler measurements.

45
Q

What does AV VTI stand for?

A

Aortic Valve Velocity Time Integral

This measurement is used to assess the effective area of the aortic valve.

46
Q

Fill in the blank: The PEDOF probe is mandatory for _______.

A

Aortic Stenosis

Aortic stenosis is a condition that requires assessment of blood flow through the aortic valve.