anxiety ds Flashcards

1
Q

anxiety facts

A

-approx 18% in US -> >40 mil adults
-treated by PCP 90% of time* (hard/expensive to get psychiatrist)
-MC mental health illness in USA
-5X more likely to seek medical care for a variety of conditions
-6X more likely to be hospitalized for a psychiatric condition

Comorbidity:
-high rates of comorbid psychiatric disorders, especially Depressive Disorder (50%)
-High rates of comorbid alcohol and drug abuse
-high rates of suicide attempts

children:
-Affects 1/8 children with strong genetic component
-Children -> increased risk of truancy (skipping school), substance abuse, being bullied and poor school performance

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2
Q

anxiety as normal vs abnormal response

A

Normal:
-Some amount of anxiety is “normal” and is associated with optimal levels of functioning
-Adaptive response to threat to self or environment

abnormal: when anxiety begins to interfere with social or occupational functioning
-can affect school, work, social relationships and physical health
- If its impacting day to day life -> mental health issue**

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3
Q

social effects of anxiety

A

-Prolonged anxiety can result in Major Depression
-less involved with family/friends the way you used to be
-Lowered quality of relationships
-Low energy, lethargy, dysphoria
-Lack of motivation to do the things you once looked forward to doing
-Unable to convey the person that you are
-Fear and avoidance of situations where previous attacks occurred

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4
Q

what is anxiety: clinical vs anthropological vs psychiatric

A

Clinical Answer:
-unpleasant emotional and physical state characterized by fear, apprehension, restlessness, tension, over-activity of the autonomic nervous system, cardiac and pulmonary sensations, and the expectation of impending disaster.

Anthropological Answer:
-“stress response” hardwired into the brain of most mammals triggered when survival is threatened.

Psychiatric Answer:
-Catecholamines: Decreased activation of serotonin and increased activation of norepinephrine
-Increased autonomic activity: increases HR, BP, force of cardiac contractions, and dilates airways in lungs

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5
Q

what is anxiety disorder? what manifestations and physical sx

A

illness that often manifests with psychological and somatic symptoms

produces:
-Intense, excessive, and prolonged states of apprehension and fear
-Autonomic arousal: elevated pulse, elevated BP, diaphoresis, rapid breathing)
-Physical discomfort: headache, dizziness, nausea, abdominal pain, diarrhea, myalgias, arthralgias

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6
Q

developmentally normal fears: chart

A

birth-6 months- Loud noises, loss of physical support, rapid position changes, rapidly approaching other objects

7-12 months- Strangers, looming objects, unexpected objects or unfamiliar people

1-5 year- Strangers, storms, animals, dark, separation from parents, objects, machines with loud noises

6-12 year- Supernatural, bodily injury, disease, burglars, failure, criticism, punishment

12-18- Performance in school, peer scrutiny, appearance, performance
6

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7
Q

ex: Nick is a 52 yr old pharmacist who can’t remember a time when he was not feeling anxious. Although he is competent at his job, he gets extremely anxious about work and feels that he might make mistakes. This worry also extends to his personal life where he is always worrying about his kids academic performance and if they are getting bullied.
He often has nightmares and feels tired and restless all the time. Although he has a great marriage, he worries constantly that he may not be able to provide for his family which causes him to have sleepless nights

A

generalized anxiety disorder pt

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8
Q

types of anxiety disorders

A

-Generalized Anxiety Disorder
-Social Anxiety Disorder
-Phobia
-Panic Disorders
-PTSD
-OCD

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9
Q

generalized anxiety disorder: definition and criteria for dx

A

Definition:
- presence of excessive anxiety and worry about various topics, events, or activities for at least 6 months
- difficulty controlling worrying: in both adults and children, the focus of the worry may easily shift from one topic to another
- must have at least 3 physical or cognitive sx (children only need one):

Sx: MEDIC - Fatigue = GAD
- muscle soreness/aches
- edginess or restlessness
- difficulty sleeping
- irritability
- concentration impaired or mind goes blank
- fatigue, tire more easily

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10
Q

social anxiety disorder: definition and criteria

A

Def:
- intense fear or anxiety specific to social situations where an individual feels scrutinized or judged by others -> causes significant distress or impairment
- individual often fears that they will display their anxiety and that this will lead to social rejection or negative judgment
- social interactions provoke distress -> avoided or painfully and reluctantly endured
- fear or anxiety experienced is grossly disproportionate to the actual threat of the situation
-sx last 6 MONTHS or longer AND
-cause personal distress and impairment of functioning in 1+ domains -> interpersonal or occupational functioning

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11
Q

social anxiety disorder: how will it show in adults vs kids and men vs women

A

EQUALLY common in men vs women*

Child:
- tends to occur with peers rather than adults
- sx: crying, cringing, or other obvious signs of distress

Adult:
- first date, job interview, meeting someone for the first time, delivering an oral presentation, speaking in class or meeting

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12
Q

-Bill is a 34 yr old accountant who was recently promoted to a mid level management position at his bank. Bill was wary about this promotion but felt he had not choice but to accept it. His fear stem from the fact that he has to make presentations to the senior management regarding projects his team is involved in.
-Weeks before any presentation, he has nightmares about how he might screw up, feels extremely anxious and his work starts suffering. Although he knows his anxiety is unreasonable, he just cannot help it.

A

social anxiety disorder example

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13
Q

phobic disorder: definition and criteria

A

-unreasonable, excessive fear
-triggered by specific object or situation
-out of proportion to actual danger
-instantaneously reacts when presented with object or situation
-goes out of way to avoid or endures with extreme distress
-significantly impacts the individuals school, work, or personal life

Criteria:
-at least 6 MONTH duration for all ages
-not caused by another disorder- first need to rule out similar conditions -> agoraphobia, OCD, separation anxiety -> before dx specific phobia
- The anxiety, panic attack, or phobic avoidance associated with the specific object or situation is not better accounted for by another mental disorder.

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14
Q

define the phobia

A
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15
Q

agoraphobia: definition

A
  • an ANXIETY disorder that causes an intense fear of becoming overwhelmed/having a panic attack or unable to escape or get help
  • Because of fear and anxiety they will avoid new places and unfamiliar situations
    -DSM 5: last more than 6 MONTHS

Ex:
-Enclosed Places
-Driving
-Public Transportation
-Crowds
-Shopping Malls and Supermarkets

not a phobic ds

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16
Q

phobia: subtypes per dsm 5

A

-Animal
-Natural environment
-Blood-injection-injury
-Situational
-Other

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17
Q

-Phyllis works at her dream job as a marketing executive for a multinational firm. Recently her firm was acquired by another company which requires her to travel to distant sites for work reasons.
-Phyllis is extremely scared of flying due to a childhood incident when she endured extreme turbulence in an airplane, which led to an emergency landing. Her frequent attempts to delay flying to places has led to disciplinary action and she is seriously contemplating leaving her current job, which she loves.

A

phobic disorder example - aviophobia (fear of flying)

not agoraphobia:
Specificity: Phyllis’s anxiety is triggered only by flying, not by public transportation or open spaces in general.
Behavior: Her fear doesn’t seem to extend to being in crowded places or far from home; it is limited to airplanes.
Context: The scenario describes avoidance of flying for work-related travel, which aligns with aviophobia (fear of flying), a type of specific phobia.

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18
Q

post traumatic stress disorder: criterion overview (A-H)

A

Criterion A: Exposure to a traumatic event
- direct experiece
- first hand witness
- learning through relative or close friend who was exposed to trauma
- repeated or extreme exposure to aversive details of trauma - ex: first responders, medics, police officers
Criterion B: Presence of at least one of the following following an event:
- Recurrent distressing memories
- Recurring nightmares
- Flashbacks
- Intense psychological distress
- Domain: Re-Experiencing
Criterion C: Avoiding thoughts, feelings, and reminders of the trauma.
- domain: avoidance
Criterion D: At least 2 negative alterations to mood and cognition:
- Amnesia of event
- Negative perception about oneself or the world
- Blaming oneself or others for trauma
- Persistent negative emotional states
- Inability to experience positive emotions
- Diminished interest in activities
- Feelings of detachment or estrangement from others
- Domain: Negative Cognition/Mood
Criterion E: At least 2 alterations in arousal and reactivity
- Irritability/Angry outbursts
- Reckless and Self-destructive behavior (Dr. Shepherd’s fast driving)
- Hypervigilance
- Difficulty sleeping
- Problems with concentration
- Domain: Hyperarousal
Criterion F: Sx must last more than one month*
Criterion G: The symptoms must cause significant distress or impairment.
Criterion H: The symptoms cannot be explained by substance use or another medical condition

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18
Q

panic disorder definition

A

Def: Recurrent unexpected panic attacks
- attacks can occur from a calm state or an anxious state

panic attack: abrupt surge of intense fear or intense discomfort that reaches a peak within minutes, and during which time 4+ sx occur: Da PANICS
- Derealization (feelings of unreality) or depersonalization (being detached from oneself), dizziness
- Palpitations or accelerated heart rate; -Paresthesias (numbness or tingling sensations).
- abdominal distress
- Nausea
- Intense fear of losing control or “going crazy.” or dying
- Chills or heat sensations; Chest pain or discomfort. Choking feeling
- SOB, sweating, shaking, smothering

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19
Q

-Bob is a 22 yr old college student what started feeling extremely anxious and felt he was having a heart attack at a stop light. There was no specific trigger he could identify prompting this sense of acute nervousness/fear. He was having difficulty breathing and the onset was abrupt.
-These feelings lasted about 15 mins and he seriously contemplated going to the nearest ED although he recognized he had feelings like this before. He always suffered from mild anxiety but these abrupt bouts of extreme nervousness were new to him.

A

panic disorder examples

20
Q

post traumatic stress disorder: criteria A + B

A

Criterion A: Exposure to death, threatened death, serious injury, or sexual violence in one (or more) of the following way(s):
-Direct experience of trauma
-Witnessing first hand trauma
-Learning relative/friend was exposed to trauma
-Repeated or extreme exposure to aversive details of trauma, typically experienced by first responders, medics, police officers, etc.

Criterion B: Presence of 1+ intrusive sx associated with the traumatic event(s) after the event(s) occurred:
-Recurrent distressing memories
-Recurring nightmares
-Flashbacks, or disassociative reactions in which person feels the trauma repeating
-Intense or prolonged psychological distress in the face of reminders
-Physical reactions in the face of reminders

21
Q

PTSD: criterion C and D

A

Criterion C: Avoidance of stimuli associated with the trauma, as evidence by one or more of the following:
-Avoidance of distressing memories and thoughts about the trauma
-Avoidance of distressing external reminders of the trauma, like people, places, conversations, and activities

Criterion D: Negative alterations to mood and cognition with 2+ of the following:
-Inability to remember important aspects of the trauma
-Exaggerated negative thoughts about oneself, others, or the world
-Blaming oneself or others for the trauma
-Persistence negative emotional state, like fear, horror, anger, guilt, or shame
-Diminished interest in activities
-Feelings of detachment or estrangement from others
-Inability to experience positive emotions

22
Q

PTSD: criterion E and F

A

Criterion E: Alterations in arousal and reactivity, as evidenced by 2+ of the following:
-Irritability and angry outbursts with little or no provocation
-Reckless and self-destructive behavior
-Hypervigilance
-Exaggerated startle response
-Problems with concentration
-Difficulty sleeping

Criterion F: Duration is 1+ month

23
Q

PTSD: criterion G and H

A

Criterion G: The disturbance causes significant distress or impairment in social, occupational, and other important areas of functioning.

Criterion H: Symptoms are not due to medication, substance use, or another medical condition

24
Q

PTSD domains

A

Re-experiencing:
- Intrusive thoughts, images, flashbacks, nightmares, or stress from cues that remind one of the event

Avoidance: Avoiding
- thinking/talking about the event, affective numbing, amnesia, derealization, depersonalization, restricted emotions (unable to have loving feelings)

Negative Cognition/Mood:
- Anhedonia (everything is bland), difficulty remembering event, sense of self-blame

Hyperarousal:
- Insomnia, hypervigilance, exaggerated startle response, difficulty concentrating, anger

25
Q

obsessive compulsive disorder overview and obsessions vs compulsions

A

Overview/definition
-men = women
-1/3 have 1st sx in childhood
-Distressing, intrusive obsessive thoughts and/or repetitive compulsive physical or mental acts.
- “If I don’t do this thing one more time -> something bad will happen to me today”

Obsessions: Recurrent THOUGHTS, impulses, or images that are experienced as intrusive and inappropriate.
-The thoughts, impulses, or images are NOT simply excessive worries about real-life problems.

Compulsions: Repetitive BEHAVIORS or mental acts that the person feels driven to perform in response to an obsession.
-They are meant to help the person ignore the obsession or decrease associated anxiety.

26
Q
A
27
Q

-A 35 yr old Afghanistan war veteran has been having trouble sleeping at night. He often has nightmares and trouble driving especially in traffic. He cringes when he hears horns blasting and has been experiencing palpitations and diaphoresis.
These episodes started after completing 3 tours of duty in Afghanistan. His wife states he gets very irritable when asked about his war experiences and recently has been drinking a lot.

A

PTSD pt

28
Q

obsessive compulsive anxiety and related disorders in this class

A

-obsessive-compulsive disorder (OCD)
-body dysmorphic disorder
-trichotillomania (hair-pulling disorder)
-hoarding disorder
-excoriation (skin-picking) disorder

29
Q

OCD presentions: what are some obsessions vs compulsions examples

A

OBSESSIONS:
-Contamination
-Pathologic Doubt
-Need for Symmetry
-Scrupulous
-Aggressive/Violent
-Sexual

COMPULSIONS:
-Cleaning/Washing
-Checking
-Arranging
-Confessing
-Counting
-Praying

30
Q

19 year-old college freshman washes his hands at least 40-50 times each day. If he does not wash his hands, he becomes progressively more anxious. He also must open and close each door three times before entering or leaving a room. If he loses count, he must start all over.
Even though he calls his behavior “silly,” he is unable to stop. Because the behavior takes up so much of his day, his grades suffered. Subsequently, he had to take a leave of absence from his university.

A

OCD example

30
Q

OCD physical symptoms

A

-Eczematous eruptions: Caused by excessive washing
-Hair loss: Caused by compulsive hair pulling (trichotillomania)
-Excoriations: Caused by compulsive skin picking (neurodermatitis)
-Behaviors aimed at reducing anxiety and preventing some future dreaded event
-Elevated risk of suicidal ideation

31
Q

obsessive compulsive anxiety disorder vs obsessive compulsive personality disorder

A

Obsessive compulsive anxiety disorder:
- obsession that lead to compulsions
-distress

Obsessive compulsive personality disorder
- need everything to be a certain way
-no distress
-they are happy to be like this
-it is their nature

32
Q

prevalence and age of onset of mental health disorders

A

GENERAL ANXIETY DISORDER IS THE MC PREVALANCE = on the test

33
Q

what are risk factors for anxiety ds

A

-Genetics: Studies have found up to a 50% concurrence rate in monozygotic twins
-Familial Factors: Many anxiety disorders demonstrate a familial pattern. First-degree relatives of patients with panic disorders have up to a 7-fold increased probability of having panic disorder
-Environment: Behavioral traits and coping mechanisms are learned consciously or subconsciously from family, friends, peers
-Stress: Loss of a loved one/employment/status/financial security; Scholastic/occupational/romantic failure

34
Q

anxiety screening process- evaluation

A

-History (medical and psychiatric)
-Medication review
-Physical examination
-Psychiatric interview
-Mental Status Exam
-Labs and Imaging studies

Hx -thyroid problem, hormonal problems, BC, steroid use, medications that cause anxiety, substance abuse, - look at organic medical conditions before dx

35
Q

drugs/meds that cause/exacerbate anxiety ds

A

Social drugs- alcohol, caffeine, nicotine

prescription drugs: corticosteroids, beta agonist, theophylline, methylphenidate

OTC drugs- decongestants

illicit drugs- cocaine, amphetamine, marijuana, LSD, K2

Drug withdrawal- alcohol, caffeine, nicotine, benzodiazepines, beta blockers, heroin, pain meds

36
Q

-Have you ever experienced a panic attack?
-Do you consider yourself a worrier?
-Have you ever had anything happen that still haunts you?
-Do you get thoughts stuck in your head that really bother you or need to do things over and over like washing your hands, checking things or count?
-When you are in a situation where people can observe you do you feel nervous and worry that they will judge you?

match screening questions for anxiety to the dx

A

-Have you ever experienced a panic attack? (Panic Disorder)
-Do you consider yourself a worrier? (GAD)
-Have you ever had anything happen that still haunts you? (PTSD)
-Do you get thoughts stuck in your head that really bother you or need to do things over and over like washing your hands, checking things or count? (OCD)
-When you are in a situation where people can observe you do you feel nervous and worry that they will judge you? (SAD)

37
Q

Anxiety ds: treatment overview and alternative txs

A

Psychotherapy: CBT, relaxation techniques, exposure + desensitivity (OCD, Phobic Disorder), response prevention (OCD)

Pharmacotherapy: SSRI - first line tx

Alternative tx:
- Acupuncture
- Aromatherapy
- Breathing Exercises (e.g., 5/2/5 method)
- Exercise
- Meditation
- Nutrition and Diet Therapy
- Vitamins
- Hobbies
- Volunteering

37
Q

anxiety treatment: Psychotherapy

A

-Cognitive Behavioral Therapy: Identify destructive thought patterns and behaviors. Replace them with more realistic and helpful ones
-Relaxation Techniques: Meditation, yoga, progressive muscle relaxation, visualization
-Exposure and Desensitization: Gradually exposing the patient to the avoided stimulus decreases the intensity of the object of anxiety (Phobic Disorder, OCD)
-Response Prevention: Prohibiting the patient from performing anxiety reducing rituals decreases the intensity and frequency of the behavior (OCD)

38
Q

anxiety treatment: Pharmacotherapy

A

SSRIs (Prozac, Lexapro): First Line Treatment!!!
- Fluoxetine (Prozac), Escitalopram (Lexapro)
- If Pregnant: Sertraline (Zoloft)
-Starting dose is lower than for Depression
-Therapeutic dose often higher than for Depression
-Side effects are more common than in Depression

SNRIS (Effexor XR, Pristiq, Cymbalta):
- Indicated in Anxiety Disorders and Depression
- Venlafaxine (Effexor XR), Pristiq, Duloxetine (Cymbalta)

Tricyclic Antidepressants:
- Clomipramine (Anafranil) indicated for OCD

Serotonin Partial Agonists
- Buspirone (BuSpar): Indicated for GAD only
- No tolerance, dependence, withdrawal, and sedation

Benzodiazepines: Not the first-line treatment, but, has more immediate onset.
-Potential Side Effects: Sedation, confusion, impaired memory, ataxia, behavioral disinhibition, respiratory depression, tolerance, dependence, withdrawal
-May lead to death in patients with impaired respiratory function (COPD, Sleep Apnea)

Antihypertensives:
-Alpha-2 Agonists (Clonidine): Reduces sympathetic activity
-Beta-blockers (Inderal - Propranolol) Decrease autonomic response (tachycardia, diaphoresis)

Anticonvulsants (Neurontin, Lyrica): Increase GABA levels in the brain

Antipsychotics (Risperdal, Geodon): Decrease dopamine in brain. Block Serotonin-2 pathways in the brain

39
Q

Emergency Room Treatment for Anxiety/Panic Attacks

A

-Calm environment and supportive therapy

Pharmacology:
-Ativan (lorazepam) 1.0-2.0 mg PO/IM/IV q 30 min PRN (benzodiazepine)
-Can consider one time dose of antipsychotic (Risperdal, Geodon)
-SSRI first line long term therapy
-Prescribe benzodiazepines only on a short term basis

Referral for cognitive behavioral therapy after

40
Q

SNRIs (Serotonin-Norepinephrine Reuptake Inhibitors): drug names and indication

A
  • drug names: Effexor XR, Pristiq, and Cymbalta
  • indicated for both anxiety and depression.
40
Q

SSRIs: drug names, what line tx and how does dosings/adr compare with depression

A

SSRIs (Prozac, Lexapro): First Line Treatment!!!
-Starting dose is lower than for Depression
-Therapeutic dose often higher than for Depression
-Side effects are more common than in Depression

41
Q

Serotonin Partial Agonists: drug name, indication, pros and cons

A

Buspirone: indicated in GAD only
- low risk of tolerance or dependence, withdrawl and sedation
- kuriakose: works but not as good as SSRIs

41
Q

Tricyclic Antidepressants: what drug has a specific indication

A

Anafranil is particularly indicated for OCD treatment

42
Q

Benzodiazepines: drug names and indication, cautions, ADRs

A

NOT FIRST LINE TX
- immediate onset

ADRs:
- Sedation, confusion, impaired memory, ataxia, behavioral disinhibition, respiratory depression
- tolerance, dependence, withdrawal

cautions:
- can lead to DEATH in pts with impaired respiratory function -> bad for COPD/sleep apnea pts
- used cautiously, especially in elderly patients: may cause delirium and increase the risk of dementia

43
Q

Antihypertensives: which drugs and what are their indications

A

-Alpha-2 Agonists (Clonidine): Reduces sympathetic activity
-Beta-blockers (Inderal) Decrease autonomic response (i.e. tachycardia, diaphoresis)

44
Q

Anticonvulsants and antipsychotics: drug names and MOA

A

Anticonvulsants (Neurontin, Lyrica): Increase GABA levels in the brain

Antipsychotics (Risperdal, Geodon): Decrease dopamine in brain. Block Serotonin-2 pathways in the brain
- consider one time dose in anxiety/panic attack in ER