Anxiety Disorders Flashcards
Define neurosis
Functional illness
- not psychotic - patients are distressed but no delusions or hallucinations
Synonymous with anxiety disorders
Pathology of anxiety disorders
When danger perceive or anticipated brain activates autonomic nervous system
- sympathetic response primes body for action - release of adrenaline and nor-adrenaline
Brain unable to distinguish between physical and psychological threat - responds to false alarm
Define specific phobias
Marked fear of specific object or situation
- > marked avoidance of such object or situation
- dogs, spiders, thunder, balloons, snakes, flying
Define panic disorder
Fear of you own physiological and psychological reactions
Bodily changes viewed as signs of impending collapse, insanity or death
Agoraphobia - Accompanying avoidance of situations that may trigger these reactions
Cognitive model of panic disorder
Internal/external trigger
- > perceived threat
- > anxiety
- > physical/cognitive symptoms
- > misinterpretation
- > further anxiety and avoidance/safety behaviours
Define generalised anxiety disorder
Worry problem
- specific content of (type 1) worries changes/varies
- includes worries about worries (type 2 worries)
Usually accompanied by low level physical symptoms
- insomnia, muscle tension, GI problems, headache
Often maintained by belief that worry is useful - positive worry beliefs
- motivates, shows responsibility etc
Social anxiety disorder
Fear of negative evaluation of others
-> avoidance of feared situations, use of safety behaviours, anticipatory anxiety and unhelpful post-mortems following social encounters
Define OCD
Obsessive Compulsive Disorder
Obsessions = unwanted recurring distressing intrusive thoughts or images
Compulsions = manage distress caused by intrusion the patient conducts neutralising behaviours
Examples of obsessions
Contamination
Doubting
Aggression or horrific impulses
Sexual imagery
Examples of compulsions
Overt - seen - washing - checking - ordering/aligning Covert - within head - praying - counting - repeating words
Cognitive behavioural model of OCD
Trigger
- > intrusive thought
- > interpretation and appraisal
- > emotion
- > neutralisation
- > consequences
Define body dysmorphic disorder
Characterised by a preoccupation with an imagined defect in appearance
- leads to time consuming behaviours - mirror gazing, comparing features to others, excessive camouflaging tactics, skin picking and seeking reassurance
Define PTSD
Post Traumatic Stress Disorder Caused by exposure to event or situation of exceptionally threatening or catastrophic nature which would be likely to cause pervasive distress in almost anyone 3 main features - re-experiencing - avoidance - hyperarousal
Problems associated with anxiety disorders
Increased autonomic arousal Avoidance Time consuming anxiety reducing behaviours Worry Procrastination/inability to make decisions Reduced concentration Impact on functioning Impaired sleep patterned Alcohol and drug dependence
Differential diagnosis of anxiety disorders
Adjustment disorders or bereavement Other functional psychiatric illness Organic disorders - endocrine - hyperthyroidism - neurological - dementia, MS, lupus - drug induced - steroids, antihypert - alcohol and illicit drug misuse and withdrawal - miscellaneous - infection, anaemia
Define neurosis
Collective term for psychiatric disorders characterised by distress
- non-organic
- discrete onset
- delusions and hallucinations absent
Define anxiety
Unpleasant emotional state involving subjective fear
- normal human experience but can become excessive or inappropriate
Types of anxiety disorders
Specific phobia Social phobia Generalised anxiety disorder Agoraphobia Panic disorder OCD
Common symptoms of neurosis
Pscyhological
- anticipatory fear of impending doom, worrying thoughts, restlessness, poor concentration and attention, irritability, depersonalisation and derealisation
CVS
- palpitations, chest pain
Resp
- hyperventilation, cough, chest tightness
GI
- abdo pain, loose stools, N+V, dry mouth
GU
- increased frequency, failure of erection, menstrual discomfort
Neuromuscular
- tremor, myalgia, headache, paraesthesia, tinnitus
Classification of neurosis
Paroxysmal anxiety - situation dependent - phobic anxiety disorder - specific phobia - agoraphobia - social phobia - situation independent - panic disorder Continuous anxiety - generalised anxiety disorder
Generalised vs espisodic anxiety
Generalised - present most of the time - excessive or inappropriate worry about normal life event - longer duration Episodic - abrupt onset - discrete episodes - severe with strong autonomic symptoms - short lived
Differential diagnosis of anxiety
Medical - hyperthyroid, hypoglycaemia, anaemia, phaeochromocytoma, Cushing’s disease, COPD, congestive cardiac failure (CCF), malignancies Substance related - Intoxication - Withdrawal - Side effects Psychiatric - eating disorders, depression, schizophrenia, OCD, PTSD
Define GAD
Generalised Anxiety Disorder
Syndrome of ongoing, uncontrollable, widespread worry about many events or thoughts that the patient recognises as excessive and inappropriate
- symptoms present most days for at least 6 months
Pathophysiology of GAD
Biological - genetic - neurophysiological - alterations in GABA, serotonin and noradrenaline Environmental - stressful life events - substance dependence
Risk factors of GAD
Predisposing
- genetics, childhood upbringing, personality type and demands for high achievement, divorced, living alone, low socioeconomic status
Precipitating
- stressful life events, unemployment, relationship problems, personal illness
Maintaining
- continuing stressful events, marital status, living alone, ways of thinking which perpetuate anxiety
Clinical features of GAD
Worry - excessive, uncontrollable Autonomic hyperactivity - sweating, increased pupil size, increased HR Tension in muscles Tremor Concentration difficulty Chronic aches Headache Hyperventilation Energy loss Restlessness Startled easily Sleep disturbance
ICD-10 criteria for GAD
A period of at least 6 months with prominent tension, worry and feelings of apprehension about everyday events and problems
At least four of the following symptoms with at least one symptom of autonomic arousal
- symptoms of autonomic arousal, palpitations, sweating, shaking/tremor, dry mouth
Differential diagnosis of GAD
Other neurotic disorder - panic, specific phobias, OCD, PTSD
Depression
Schizophrenia
Personality disorder
Excessive caffeine or alcohol consumption
Withdrawal from drugs
Organic - anaemia, hyperthyroidism, phaeochromocytoma, hypoglycaemia
Management of GAD
Biological - SSRIs - sertraline - 1st line - SNRIs and pregabalin - benzodiazepines only for short term due to dependence Psychological - psychoeducational groups - low intensity - CBT - high intensity - applied relaxation Social - self help - writing down thoughts - support groups - exercise
Step care model for management of GAD
Step 1 - identification and assessment - psychoeducation - monitoring Step 2 - low intensity psychological interventions Step 3 - high intensity psychological interventions - drug treatment Step 4 - highly specialised input - combination of drug and psychological therapies - crisis team
Define phobia
Intense, irrational fear of an object, situation, place or person that is recognised as excessive or unreasonalbe
Define agoraphobia
Fear of public spaces or entering a public space from which immediate escape would be difficult in the event of a panic attack
Define social phobia
Fear of social situations which may lead to humiliation, criticism or embarrassment
Risk factors for phobias
Adverse experiences Stress and negative life events Other anxiety disorders Mood disorders Substance misuse disorders Family history
Clinical features of phobias
Biological - tachycardia - vasovagal response (bradycardia) in need and blood phobias -> syncope Psychological - anticipatory anxiety - inability to relax - urge to avoid situation - fear of dying
ICD-10 criteria for agoraphobia
Marked and consistently manifest fear in or avoidance of at least two of the following
- crowds
- public spaces
- travelling alone
- travelling away from home
Symptoms of anxiety in the feared situation with at least two symptoms present together
- at least one symptom of autonomic arousal
Significant emotional distress due to the avoidance or anxiety
- recognised as excessive or unreasonable
Symptoms restricted to feared situation
ICD-10 criteria for social phobia
Marked fear or marked avoidance of being the focus of attention or fear of acting in a way that will be embarrassing or humiliating
At least two symptoms of anxiety in the feared situation
- blushing
- fear of vomiting
- urgency or fear of micturition/defecation
Significant emotional distress due to the avoidance or anxiety
- recognised as excessive or unreasonable
Symptoms restricted to feared situation
ICD-10 criteria for specific phobia
Marked fear or avoidance of specific object or situation that is not agoraphobia or social phobia
Symptoms of anxiety in the feared situation
Significant emotional distress due to the avoidance or anxiety
- recognised as excessive or unreasonable
Symptoms restricted to feared situation
General management of phobias
Establish good rapport with patient
Avoidance of anxiety-inducing substances - caffeine
Screen for co-morbidities - substance misuse and personality disorders
Refer to specialist if there is a risk of self-harm, suicide, self-neglect or significant co-morbidity