Anxiety disorders Flashcards

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1
Q

what is the epidemiology of anxiety disorder?

A

2:1 F:M

Apart from PTSD which is more common in men

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2
Q

list the anxiety disorder in their order of prevalence?

A
  1. Specific phobia
  2. Social phobia
  3. PTSD
  4. Generalised anxiety disorder
  5. Panic
  6. Agoraphobia - without panic
  7. OCD
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3
Q

whats the icd10 criteria for agroaphobia?

A

The uniting fear in agoraphobia is of being unable to
easily escape to a safe place (usually home). Agoraphobia
includes fear of open places and fear of situations that are
confined and difficult to leave without attracting attention.

The overwhelming urge is to return home to safety.

These situations can include open spaces, public transit, shopping centers, or simply being outside their home.
Fear of travelling from home/alone

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4
Q

what are the theories outlining the aetiology of anxiety disroders?

A
  1. Genetics;
    - Fhx increases risk
    - People with high neuroticism scores are more
    likely to experience anxiety, guilt, depression, and anger
  2. Life events and childhood adversity
  3. Neurochemical
    - the fact that drugs targetting NA, GABA and serotonin
    are successful in treating anxiety is evidence that
    these factors are implicated
  4. Behaviour and cognitive theoriess
    - classical conditioning pair neutal stimulus to
    frightening one
    - negative reinforcement: escaping from a fearful
    stimulus relieves anxiety so maintains the fear
    response as not facing fears
    - cognitive theories : worrying thoughts = automatically
    repeated = causes and maintains anxiety
    - attachment theories : insecurely attached children
    become anxious adults
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5
Q

what is the icd-10 diagnostic criiteria for anxiety - GAD?

updated 05/21

A

A period of at least six months with prominent tension, worry and feelings of apprehension, about every-day events and problems

Anxiety is not triggered by a specific stimulus - its continuous and generalized (‘free-floating’).

At least four symptoms out of the following list of items must be present, of which at least one from items 1 is from Autonomic arousal symptoms;
palpitations or pounding heart, or accelerated heart rate
sweating
trembling or shaking
dry mouth (not owing to medication or dehydration)

other sx in systems;

  1. chest and abdo
  2. GI
  3. brain
  4. general
  5. tension/motor eg tremor and inability to rest

see lass

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6
Q

what are the differentials for anxiety?

A

• Hyperthyroidism

• Substance misuse:
– intoxication (e.g. amphetamines)
– withdrawal (e.g. benzodiazepines, alcohol).

• Excess caffeine.

• Depression: anxiety is a common feature of depression
—and depression complicates anxiety.

Diagnose mixed anxiety and
depressive disorder if there are low-level depressive and
anxiety symptoms present equally together, neither of
which justifies diagnosis alone. if full-blown depression and GAD are present, diagnose them both.

• Anxious (avoidant) personality disorder: from late
adolescence onwards, the patient describes themselves
as ‘an anxious person’, with no recent major increase
in anxiety levels.

• Dementia: anxiety may be an early feature of this.
• Schizophrenia: in early schizophrenia, anxiety may
occur before delusions and hallucinations are evident

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7
Q

what is the icd10 diagnostic criteria for phobic anxiety disorders

A

intermittent anxiety occurs in specific
but quite ordinary circumstances.

Patients characteristically
avoid feared situations and the seriousness of the
phobia depends on the resultant disability

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8
Q

what can improve agoraphobia?

A

The presence of a dependable companion (or sometimes a car) increases range and makes otherwise avoided
situations bearable.

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9
Q

in which scenarios may a suffere of agoraphobia be symptom free?

A

If the patient is successfully avoidant of all triggers,
they might currently experience little or no anxiety. Ask
about the past.

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10
Q

ddx for agoraphobia?

A
  1. Depression can cause social withdrawal and is commonly
    comorbid with agoraphobia.
  2. Social phobia: the fear here is of scrutiny or humiliation.
  3. Obsessive–compulsive disorder: time-consuming
    rituals can confine people to their home.
  4. Schizophrenia: patients may stay at home because of
    social withdrawal or as a way of avoiding perceived
    persecutors.
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11
Q

what is the epidemiology of social phobia?

A

late teens

men and women equally affected.

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12
Q

what are the symptoms in social phobia?

A

The core fear in social phobia is of being scrutinized or criticized by other people, and patients often worry that they will embarrass themselves in public.

They tolerate an anonymous crowd, UNLIKE
agoraphobic patients, but small groups (e.g. dinner
parties, board meetings) feel very intimidating.

There are sometimes specific worries, such as eating in public.

Self-medication with alcohol or drugs perpetuates the
problem as it offers psychological avoidance.

Patients complain most about embarrassing symptoms, e.g. blushing,
trembling, sweating, and urinary frequency.

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13
Q

what are the differentials for social phobia?

A
  1. Shyness: some people are naturally shy and feel
    uncomfortable in social situations. In social phobia,
    there is overt fear.
  2. Agoraphobia: the need to get somewhere safe is
    more important than the fear of scrutiny.
  3. Anxious (avoidant) personality disorder: there is a
    lifelong history of disabling shyness and anxiety.
  4. Poor social skills/autistic spectrum disorders
    (e.g. Asperger’s syndrome): people who are socially
    awkward will not show good social skills when
    relaxed—they remain awkward.
  5. Benign essential tremor: this tremor is familial, worse
    in social situations, and responds to benzodiazepines
    and alcohol. There are no other features of anxiety
  6. Schizophrenia/psychosis: patients may avoid social
    situations because of paranoia or because they have
    delusions that they are being watched. Patients with
    social phobia recognize that their fears are exaggerated.
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14
Q

what is a specific phobia? define it

A

These phobias are restricted to a single, specific situation
(e.g. spiders = arachnophobia).

a fear that is out of proportion to the stimulus

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15
Q

icd-10 criteria for panic disorder?

A

Anxiety is intermittent and with NO OBVIOUS TRIGGER
—it comes ‘out of the blue’.

A panic attack is a sudden attack of extreme (‘100%’) anxiety with accompanying
physical symptoms, such as:

  • breathing difficulties/choking feelings
  • chest discomfort/tightness, palpitations, tingling

fears that they will die, lose control, become incontinent, or go mad. These
thoughts provoke further panic until the patient gains
reassurance or engages in safety behaviours.

For a diagnosis of panic disorder, there must be recurrent
panic attacks (preferably several within a month).
In between episodes, the person should be relatively
free of anxiety.

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16
Q

episodic paroxysmal anxiety is aka?

A

panic attack

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17
Q

name some examples of safety behaviours that can be adopted in panic disorder?

A

calling an ambulance, taking aspirin.

Panic attacks are
self-limiting, lasting no more than 30 minutes, although
this can feel never-ending

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18
Q

name some ddx for panic disorders?

A
  1. Other anxiety disorder: especially GAD and
    agoraphobia.
  2. Depression: if depressive symptoms preceded the
    panic attacks or the criteria for depressive disorder
    are fulfilled, the diagnosis of depression takes
    precedence.
  3. Alcohol or drug withdrawal can cause severe anxiety
    that may be mistaken for panic attacks.
  4. Organic causes: exclude cardiovascular and respiratory disease
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19
Q

what ivx would you conduct for panic disorder in order?

A
  1. A good history and physical examination. Rule out organic causes:

alcohol, drug withdrawal
urine drug screen
Bloods: TFTs - rule out hyperthyroid

————-above is what lecture said.————-

  1. Rating scales of anxiety include the
    Beck Anxiety Inventory
    HADS (Hospital Anxiety and Depression Scale)

These can assess severity or provide
baseline ‘scores’ against which to measure treatment
response.

  1. Social and occupational assessments for effect on
    quality of life.
  2. Collateral history.
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20
Q

how is panic disorder managed according to NICE?

A

Acutely:
Reassure and brown bag for breathing
Benzodiazepines in emergency situation

Mild to moderate

  1. individual non-facilitated self-help (eg CBT)
    OR
  2. individual facilitated self-help
    -> follow up every 1-2 months

Moderate to severe panic disorder (with or without agoraphobia):
1. CBT (1-2 weekly for 4 months) OR
2. Antidepressant SSRI
(if long-standing or the person has not benefitted from psychological intervention)

  1. if a combination of medication and psych intervention has been tried but failed;
    refer to mental health services
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21
Q

which antidepressants can be used in panic disorder?

A

Escitalopram,
citalopram
sertraline,
paroxetine and venlafaxine

so ssris and snris

monitor for suicidal thoughts etc

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22
Q

what is the purpose of CBT in panic disorder?

what elements are included?

A

educates patient that their symptoms mean panic not perish, ie are not a sign pn catastrophe

help them to not misinterpret their symptoms

elements included
exposure therapy:
trying to get patient ‘used to a fear’ through desensitisation.
goal is to stay in situation until anxiety has subsided
step by step approach

23
Q

what other drugs but antidepressants can be useful in panic attack?

A

beta-blockers for adrenergic symptoms

24
Q

prognosis of panic disorder?

A

1/3 recover

1/3 partial improvement

1/3 poor qol, considerable disability

25
Q

define ocd?

A

Obsessive–compulsive disorder is a mental disorder in which a person feels the need to perform certain routines repeatedly (called “compulsions”), or has certain thoughts repeatedly (called “obsessions”).

26
Q

what is the icd-10 criteria for OCD?

A

People with OCD cannot ignore unpleasant intrusive
anxiety-producing thoughts (Obsessions)

and may try to relieve them with (compulsions) repeated rituals.

symptoms must be present on most days of the week for more than 2 weeks

can present with sx resulting from their compulsion i.e. dermatitis from excessive handwashing.

these symptoms HAVE TO BE DISTRESSING to be characterised as OCD

they can have obsessions ALONE or compulsions ALONE or both.

27
Q

epidemiology of ocd?

A

m=f

1%

28
Q

aetiology of ocd?

A
  1. Genetics
    - FHx inc risk 3x
    - 1/4 have anankastic personality traits (rigidity,
    orderliness)
    - deficit in frontal-lobe inhibition
    - Anti-basal ganglial antibodies (post strep throat)
29
Q

list some themes of obsessions in ocd?

A
  • contamination
  • aggression (thoughts of harming self or others)
  • infection
  • morality (commonly sex/religion).
30
Q

describe obsessions in ocd

A

patient recognises them as irrational / not their own

attempts to resist them to no avail

31
Q

list some differentials in ocd?

A
  1. Anxiety disorders: obsessional symptoms are less
    prominent than other anxiety symptoms.
  2. Depression: obsessions can occur within depression
    and up to 50% of patients with OCD experience
    depressive symptoms. If the episode meets the criteria
    for depression, this takes priority.
  3. Anankastic personality disorder: a lifelong personality
    of rigidity, often with very high standards of
    orderliness, hygiene, etc. The pattern of obsessions and
    compulsions is absent unless OCD is superimposed.
  4. Schizophrenia: beliefs are delusional not obsessional.
  5. Organic causes: rarely, e.g. Sydenham’s chorea.
32
Q

prognosis of ocd?

A

OCD tends to run a chronic course, with symptoms
worsening at times of stress. It is often disabling and
commonly comorbid with depression.

33
Q

how is OCD managed?

in adults and children?

A

Children Mild
-> guided self help w/family

Children Moderate - Severe
CBT 1st
Fluoxetine - only post referall to CAMHS
sometimes clomipramine

Adults Mild
Individual CBT or group CBT ; that includes exposure response therapy (ERT)

Adults Moderate
Intense CBT + ert or SSRI - high dose

Adult Severe
CBT (+ ert) + SSRI

34
Q

what does exposure and response therapy involve?

A

example; someone with obsessions
about contamination is supported to touch something
dirty (e.g. dustbin)

35
Q

characterise acute stress reaction

A

state of shock
follows traumtic events

transient, acute onset from trauma
resolves; hours - 3 days max

sx;
anxious, dazed, depersonalisation, irritable etc

36
Q

how is an acute stress reaction managed?

prognosis?

A

supportive, reassurance; it is a self limiting condition

Benzodiazepines - for short term distress

prognosis; increased risk of PTSD later

37
Q

what is the icd-10 criteria for ptsd?

updated

A

must follow traumatic event

The event suffered or witnessed by
the patient must be ‘an event of an exceptionally threatening or catastrophic nature likely to cause pervasive. distress in anyone’

3 main domains:
Exposure to traumatic event
1. Relieving event - flashbacks/nightmares
2. hyperarousal
3. avoidance of reminders OR inability to recall all/parts of experience

must have significant impact on life!

38
Q

epediomology of ptsd?

A

F>M

7% lifetime prevalence

Only about 10% of people who experience
an extreme trauma develop PTSD

39
Q

aetiology of ptsd?

A

genetic - 1/3rd

neurotic traits, a personal or
family history of psychiatric problems, childhood abuse,
and poor early attachment.

‘Survivor guilt’ and continual
exposure to the trauma or other stressors can perpetuate
symptoms

In PTSD, the amygdala (emotional processing)
is hyperactive and the hippocampus (memory
storage) is atrophied.

40
Q

how is memory different in ptsd sufferers compared to other people?

A

distortion in the processing and storage of traumatic
events such that they are constantly ‘relived’ rather than
‘remembered’.

In PTSD, the amygdala (emotional processing)
is hyperactive and the hippocampus (memory
storage) is atrophied.

41
Q

describe the presentation of ptsd?

A

PTSD usually begins within 6 months:

  • Flashbacks: vividly reliving the trauma
  • Nightmares.
  • Intrusive memories

• Avoidance: Avoiding reminders of the event
• Hyperarousal
-> Persistent inability to relax
-> insomnia
-> on red alert constantly: Hypervigilance
• Emotional detachment (‘numbness’).
• Decreased interest in activities.

there may be difficulties in remembering the entire episode voluntarily.

42
Q

how is ptsd managed according to NICE?

A

Individual trauma-focused CBT

Eye movement desensitisation and reprocessing (EMDR)
- if presenting 3+ months after non-combat related
trauma

Drugs;- if they prefer drugs
SSRI - Sertraline or
SNRI - venlafaxine

Tretament failure + Disabling hyperarousal or psychotic sx;
Respiridone

43
Q

what does Individual trauma-focused CBT involve?

A

cognitive processing therapy

cognitive therapy for PTSD

narrative exposure therapy

prolonged exposure therapy

44
Q

what is ana adjustment disorder?

A

Examples include going to university, breaking up with a partner, or moving house.

symptoms of anxiety, low mood, irritability, or sleeplessness.

Symptoms start within a month of the stressor and resolve within six months.

the person’s reaction is deemed greater than usually expected for the situation, but not
severe enough to diagnose an anxiety or depressive
disorder.

45
Q

rx for adjustment disorders?

A

Support, reassurance, and problem-solving are often all

that are needed.

46
Q

aetiology of anxiety?

A

phaechromocytoma
hyperthyroidism

etc

47
Q

epidemiology of agoraphobia?

A

women 4x risk
80% married - attached/dependent on spouse
50% get panic attacks

48
Q

house bound
panic attack
dependent on another person

are signs of?

A

agoraphobia

49
Q

prognosis of social phobia?

A

present for life

comorbid depression

50
Q

what is the management of phobias?

A
  1. CBT with exposure therapy
    - 12 weeks, weekly sesh
    - desensitisation
    - exposure to feared stimulus in grades
    - encourgaed not to run (avoidant behaviour), anxiety improves/habituation
    - homework
  2. Medication; (used if v severe that cant utilise therapy)
    SSRIs
    B-blockers - for acute sx ; short term
51
Q

Epidemiology of panic disorder?

A

women 2x risk

52
Q

what do you need to remember about generalised anxiety?

A

Continuous - everydayfor at least 6 months
no triggers

ivx:
includes rating scales eg. GAD-7

ddx:
includes caffeine and depression

53
Q

what are the 3 reactions in adjustment disorder?

A

brief depressive reaction
<1 month

prolonged depressive reaction
<2 years

mixed anxiety and depression

54
Q

complications of ptsd?

prognosis?

A

suicidality
substance misuse

most recover - anniveersaires can bring relapses