Anxiety Disorders Flashcards

1
Q
  • Anxiety
A

A general feeling of apprehension about possible danger.
Adaptive value - helps us plan and prepare for possible threat, in mild to moderate degrees.
Most of our sources of fear and anxiety are learned.
Future-oriented and diffuse than fear
Cognitive/subjective, physiological, and behavioral components
Physiology - misfiring of neurons

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2
Q
  • Fear
A

A basic emotion that involves the activation of the “fight-or-flight” response of the sympathetic nervous system.

To theorists it is adaptive and allows us to escape.

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3
Q
  • OCD
A

Anxiety disorder characterized by the persistent intrusion of unwanted and intrusive thoughts or distressing images; these are usually accompanied by compulsive behaviors designed to neutralize the obsessive thoughts or images or to prevent some dreaded event or situation.

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4
Q
  • Obsessions
A
Persistent and recurrent intrusive thoughts, images, or impulses that a person experiences as disturbing and inappropriate but has difficulty suppressing. 
Examples:
- Contamination fears
- Fears of harming oneself or others
- Lack of symmetry
- Pathological doubt
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5
Q
  • Neurotic Disorders
A

Psychodynamic term for anxiety-driven mental health conditions that are manifest through avoidance patterns and defensive reactions.

Freud - disorders developed when intrapsychic conflict produced significant anxiety. He believed anxiety was a sign of an inner battle or conflict between some primitive desire (from the id) and prohibitions against its expression (from the ego and superego).

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6
Q
  • Panic Attack
A

A severe, intense fear response that appears to come out of the blue; it has many physical and cognitive symptoms such as fear of dying or losing control.

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7
Q
  • Anxiety Disorders
A

An unrealistic, irrational fear or anxiety of disabling intensity. DSM-IV-TR recognizes seven types of anxiety disorders:

  • phobic disorders (specific or social)
  • panic disorder (with or without agoraphobia)
  • generalized anxiety disorder
  • obsessive-compulsive disorder
  • posttraumatic stress disorder.
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8
Q
  • Phobia
A

Persistent and disproportionate fear of some specific object or situation that presents little or no actual danger.

Three main categories of phobias: (1) specific phobia, (2)social phobia, and (3) agoraphobia.

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9
Q
  • Specific Phobia
A

Strong and persistent fear recognized as excessive or unreasonable
Triggered by a specific object or situation

leads to a great deal of avoidance behavior; when confronted with a feared object, the phobic person often shows activation of the fight-or-flight response, which is also associated with panic.

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10
Q
  • Blood-Injection-Injury Phobia
A

Persistent and disproportionate fear of the sight of blood or injury, or the possibility of having an injection. Afflicted persons are likely to experience a drop in blood pressure and sometimes faint.
Exhibit response characteristic of “fight-or-flight”

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11
Q
  • Prepared Learning
A

The view that people are biologically prepared through evolution to more readily acquire fears of certain objects or situations that may once have posed a threat to our early ancestors. (not born in, easily acquired)
For example, people more readily develop fears of snakes and spiders if they are paired with aversive events, than they develop fears of knives or guns.

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12
Q
  • Social Phobia
A

Disabling fears of one or more specific social situations
Social anxiety disorder
Fear of exposure to scrutiny and potential negative evaluation of others and to humiliation or embarrassment

  • may actually experience panic attacks in social situations.
  • have prominent perceptions of unpredictability and uncontrollability
  • preoccupied with negative self-evaluative thoughts that tend to interfere with their ability to interact in a socially skillful fashion.
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13
Q

Cognitive Restructuring

A

Cognitive-behavioral therapy techniques that aim to change a person’s negative or unrealistic thoughts and attributions.

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14
Q
  • Panic Disorder
A

Occurrence of repeated unexpected panic attacks, often accompanied by intense anxiety about having another one.
Attacks are brief but intense
13 possible symptoms of panic attacks, 10 of which are physical and 3 of which are cognitive:
(1) depersonalization (a feeling of being detached from one’s body) or derealization (a feeling that the external world is strange or unreal);
(2) fear of dying; or
(3) fear of “going crazy” or “losing control”

as many as 85% of people having a panic attack may show up repeatedly at emergency rooms or physicians’ offices for what they are convinced is a medical problem—usually cardiac, respiratory, or neurological

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15
Q
  • Agoraphobia
A

Fear of being in places or situations where a panic attack may occur and from which escape would be physically difficult or psychologically embarrassing, or in which immediate help would be unavailable in the event that some mishap occurred.

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16
Q
  • Panic Provocation Procedures (definition)
A

A variety of biological challenge procedures that provoke panic attacks at higher rates in people with panic disorder than in people without panic disorder.

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17
Q
  • Anxiety Sensitivity
A

A personality trait involving a high level of belief that certain bodily symptoms may have harmful consequences.

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18
Q
  • Generalized Anxiety Disorder
A

Chronic excessive worry about a number of events or activities, with no specific threat present, accompanied by at least three of the following symptoms: restlessness, fatigue, difficulty concentrating, irritability, muscle tension, sleep disturbance.
• Occurs more days than not for 6-month period

a relative lack of safety signals may help explain why people with GAD feel constantly tense and vigilant for possible threats

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19
Q

Hoarding Disorder

A

A new DSM-5 diagnosis characterized by long-standing difficulties discarding possessions, even those of little value.

  • acquire and fail to discard many possessions that seem useless or of very limited value, in part because of the emotional attachment they develop to their possessions
  • disorganization in living space interferes with daily life
  • poorer prognosis for treatment than OCD
  • occurs in approximately 10–40% of people with OCD
  • prevalence may be 3–5% of general population
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20
Q

Compulsions

A
Overt repetitive behaviors or more covert mental acts that a person feels driven to perform in response to an obsession. 
Examples:
- Cleaning
- Checking
- Repeating
- Ordering/arranging
- Counting
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21
Q
  • What are the clinical features of Panic Disorder?
A

recurrent, unexpected panic attacks that often create a sense of stark terror

  • numerous other physical symptoms of the fight-or-flight response
  • panic attacks usually subside in a matter of minutes.
  • many develop anxious apprehension about experiencing another attack; this apprehension is required for a diagnosis of panic disorder.
  • many also develop agoraphobic avoidance of situations in which they fear that they might have an attack.
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22
Q

Body Dysmorphic Disorder

A
  • obsessed with perceived or imagined flaw(s) in their appearance
  • firmly believe they are disfigured or ugly
  • this preoccupation is so intense that it causes clinically significant distress and impairment in social or occupational functioning.
  • moved from somatoform disorders to OCD disorders because of its commonalities with OCD
  • most common locations of complaints are skin, hair, nose, eyes, breasts/chest/nipples, stomach, face size/shape
  • causes still being researched. There is some heritability and some issues with self-schema
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23
Q

Trichotillomania

A
  • Urge to pull out hair from any body location
  • Preceded by tension and followed by pleasure
  • Must cause clinically significant distress
  • Trichotillomania moved from impulse-control disorders to OCD-related disorders in DSM-5
  • Not much is known about the disorder
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24
Q
  • Cognitive Theory of Panic Disorder
A

holds that this condition may develop in people who are prone to making catastrophic misinterpretations of their bodily sensations, a tendency that may be related to preexisting high levels of anxiety sensitivity.

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25
Q
  • Clinical Aspects of Generalized Anxiety Disorder
A
  • chronic and excessively high levels of worry about a number of events or activities
  • responds to stress with high levels of psychic and muscle tension.
  • may occur in people who have had extensive experience with unpredictable or uncontrollable life events.
  • seem to have danger schemas about their inability to cope with strange and dangerous situations that promote worries focused on possible future threats
  • often functional deficiency in the neurotransmitter GABA, which is involved in inhibiting anxiety in stressful situations; the limbic system is the brain area most involved.
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26
Q

Clinical features of OCD

A

experiences unwanted and intrusive distressing thoughts or images that are usually accompanied by compulsive behaviors performed to neutralize those thoughts or images.
i.e. checking and cleaning rituals are most common.

evidence from genetic studies, studies of brain functioning, and psychopharmacological studies.

once this disorder begins, the anxiety-reducing qualities of the compulsive behaviors may help to maintain the disorder.

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27
Q

What are the three obsessive-compulsive related disorders

A

body dysmorphic disorder
hoarding disorder
trichotillomania

28
Q
  • Fear and panic have three components:
A

(1) cognitive/subjective components (“I feel afraid/terrified”; “I’m going to die”)
(2) physiological components (such as increased heart rate and heavy breathing)
(3) behavioral components (a strong urge to escape or flee)

29
Q
  • Fear and anxiety response patterns
A

Difficult to completely distinguish between fear and anxiety.
Historically, distinction centered on whether source of danger is obvious.
Obvious danger leads to fear
Less obvious danger leads to anxiety.

30
Q
  • Specific Phobia Subtypes Identified by the DSM-5
A
Animal
Natural environment
Blood-injection-injury
Situational
Other
31
Q
  • Specific Phobias: Prevalence, Age of Onset, and Gender Differences
A
  • Common mental disorders
  • Lifetime prevalence rate of about 12%
  • More common in women than men
  • Blood-injection-injury phobia occurs in about 3-4% of population
  • Age of onset for different phobias varies widely
32
Q
  • Psychological Causal Factors of Anxiety Disorders
A

Psychoanalytic viewpoint: defense against anxiety stemming from repressed id impulses
- defense mechanisms do not work, leaving the person anxious nearly all the time.
Learned behavior/classical conditioning
Vicarious conditioning
Individual differences in learning
Evolutionary preparedness

33
Q
  • Psychological Causes of OCD
A

Mowrer developed the two-process theory of avoidance learning
Neutral stimuli become associated with fearful thoughts via classical conditioning
Examples:
- Obsessions with contamination and dirt appear to have evolutionary roots
- Attempting to suppress unwanted thoughts may increase those thoughts
- Cognitive biases toward material relevant to one’s obsessive concerns

34
Q
  • Psychological Causes of Social Phobias
A

(1) Learned behavior
- Classical conditioning that is direct or vicarious in nature
i. e. experiencing or witnessing a perceived social defeat or humiliation, or being or witnessing the target of anger or criticism
(2) Evolutionary factors
- Predisposition based on social hierarchies
- evolutionarily based predisposition to acquire fears of social stimuli that signal dominance and aggression from other humans.
(3) Perceptions of uncontrollability and unpredictability
- often lead to submissive and unassertive behavior, which is characteristic of socially anxious or phobic people
- diminished expectation of personal control may develop, at least in part, as a function of having been raised in families with somewhat overprotective parents
(4) Cognitive biases toward “danger schemas” in social situations

35
Q
  • Panic Disorder: Prevalence, Age of Onset, and Gender Differences
A
  • 4.7% of adult population have had panic disorder at some time in their lives
  • Twice as prevalent in women as men
  • Average age of onset is 23–34 years
  • Panic disorder without agoraphobia more common than panic disorder with agoraphobia
36
Q

Panic Disorder Comorbidity with Other Disorders

A
  • 83% of people with panic disorder have at least one comorbid disorder
  • 50–70% will experience serious depression at some point in their lives
  • Panic disorder associated with suicidal ideation and suicide attempts independent of comorbidity
37
Q
  • Timing of a First Panic Attack
A
  • First attack frequently follows feelings of distress or highly stressful life circumstance
  • Many adults who experience single panic attack do not develop panic disorder
38
Q
  • Generalized Anxiety Disorder: Prevalence, Age of Onset, and Gender Differences
A
  • Each year 3% of population experiences GAD
  • Lifetime prevalence is 5.7%
  • Twice as common in women as in men
  • 60–80% report having been anxious nearly all their lives, so age of onset is difficult to determine
39
Q
  • OCD: Prevalence, Age of Onset, and Gender Differences
A
  • One-year prevalence is 1.2%
  • Lifetime prevalence is 2.3%
  • Lifetime prevalence is some studies is as high as 3%
  • OCD affects both genders about equally
  • Typically begins in adolescence or early adulthood
  • Divorced (or separated) and unemployed individuals overrepresented
  • Also not uncommon in children: more frequent in boys than girls and greater in severity
40
Q
  • OCD and comorbidity with other disorders
A
  • Frequently co-occurs with other anxiety disorders and mood disorders
  • Also co-occurs with body dysmorphic disorder
  • Depression very common comorbid disorder
41
Q

Body Dysmorphic Disorder: Prevalence, Age of Onset, and Gender Differences

A

• General population prevalence is 1-2%
• People with depression, prevalence is 8%
- Suicide attempts and ideations are also common
• BDD affects both genders about equally
• Typically begins in adolescence

42
Q

Body Dysmorphic Disorder and its relationship with other disorders

A
  • Similar behaviors and causes as OCD

* Shares body image distortions with eating disorders

43
Q

Obsessive-Compulsive Disorders Treatments

A
  • Many people do not know what treatment options are available to them
  • Many therapists are not trained in specialized treatments for these classes of disorders

• Exposure and response prevention may be most effective approach to obsessive-compulsive disorder
- Exposure to anxiety-producing obsession, prevention of compulsion typically used
- Gradually move through hierarchy of stimuli
• Medications that affect neurotransmitter serotonin have also been found helpful

44
Q
  • Neuroticism
A

a proneness or disposition to experience negative mood states that is a common risk factor for both anxiety and mood disorders

45
Q

The brain structures most centrally involved in most disorders

A

are generally in the limbic system (often known as the “emotional brain”) and certain parts of the cortex, and the neurotransmitter substances that are most centrally involved are GABA, adrenaline, and serotonin

46
Q

Sociocultural effect on fear and anxiety

A

ociocultural environment in which people are raised also has prominent effects on the kinds of objects and experiences people become anxious about or come to fear.

47
Q

Vicarious Conditioning

A

Simply watching a phobic person behaving fearfully with his or her phobic object can be distressing to the observer and can result in fear being transmitted from one person to another through vicarious or observational classical conditioning.

Watching a
nonfearful person undergoing a frightening experience can also lead to vicarious conditioning.

i.e. rhesus monkeys

48
Q
  • Individual Differences in Learning
A

differences in life experiences among individuals strongly affect whether or not conditioned fears or phobias actually develop

life experiences may serve as risk factors and make certain people more vulnerable to phobias than others, and other experiences may serve as protective factors for the development of phobias

49
Q

Inflation Effect

A

suggests that a person who acquired, a mild fear of driving following a minor crash might be expected to develop a full-blown phobia if he or she later were physically assaulted, even though no automobile was present during the assault

50
Q

Biological Causal Factors of Fear

A

Genetic and temperamental variables affect the speed and strength of conditioning of fear
Researchers found that individuals who are carriers of one of the two variants on the serotonin-transporter gene (the s allele, which has been linked to heightened neuroticism) show superior fear conditioning relative to individuals who do not carry the s allele.
A twin study found that monozygotic twins were more likely to share animal phobias and situational phobias than were dizygotic (nonidentical) twins
Heritability of animal phobias was separate from the heritability of complex phobias such as social phobia and agoraphobia

51
Q

Biological Causal Factors of Social Phobia

A

The most important temperamental variable is behavioral inhibition, which shares characteristics with both neuroticism and introversion
- most likely to become anxious

Results from several studies of twins have also shown that there is a modest genetic contribution to social phobia; estimates are that about 30% of the variance in liability to social phobia is due to genetic factors

people with a history of social or specific phobia are at heightened risk for developing panic disorder

52
Q
  • Panic and the Brain
A

Panic attack: arise from activity in the amygdala, either by cortical inputs (e.g., evaluating a stimulus as highly threatening) or by activity coming from more downstream areas like the locus coeruleus.

Phobic avoidance: the hippocampus (part of the limbic system, below the cortex) which is very involved in the learning of emotional responses, is thought to generate conditioned anxiety

53
Q
  • What are the current two panic provocation systems?
A

(1) the noradrenergic system
- can stimulate cardiovascular symptoms associated with panic
- By decreasing noradrenergic activity, these medications decrease many of the cardiovascular symptoms associated with panic that are ordinarily stimulated by noradrenergic activity.
(2) the serotonergic systems
- increased serotonergic activity decreases noradrenergic activity.
- SSRIs seem to increase serotonergic activity in the brain but also to decrease noradrenergic activity.

GABA has also been implicated in the anticipatory anxiety that many people with panic disorder have about experiencing another attack.
- inhibit anxiety and has been shown to be abnormally low in certain parts of the cortex in people with panic disorder

54
Q

Automatic Thoughts

A

Beck

  • The person is not necessarily aware of making these catastrophic interpretations; rather, the thoughts are often just barely out of the realm of awareness
  • In a sense are the triggers of panic
55
Q
  • Learning and Cognitive Explanations of Results form Panic Provocation Studies
A

The key difference between these two theories:
importance the cognitive model places on the meaning that people attach to their bodily sensations; they will experience panic only if they make catastrophic interpretations of certain bodily sensations.
Such catastrophic cognitions are not necessary with the interoceptive conditioning model because anxiety and panic attacks can be triggered by unconscious interoceptive (or exteroceptive).

The learning theory model is better able to explain the occurrence of the panic attacks that often occur without any preceding negative (catastrophic) automatic thoughts, as well as the occurrence of nocturnal panic attacks that occur during sleep; the occurrence of both of these kinds of attacks is difficult for the cognitive model to explain

56
Q
  • Perceived Control
A
  • reduces anxiety and blocks panic
  • if a person with panic disorder is accompanied by a “safe” person
    when undergoing a panic provocation procedure, that person is likely to show reduced distress, lowered physiological arousal, and reduced likelihood of panic relative to someone who came alone
57
Q
  • Several of the benefits that people with Generalized Anxiety Dissorder most commonly think derive from worrying are:
A

(1) Superstitious avoidance of catastrophe (“Worrying makes it less likely that the feared event will occur”).
(2) Avoidance of deeper emotional topics (“Worrying about most of the things I worry about is a way to distract myself from worrying about even more emotional things, things that I don’t want to think about”).
(3) Coping and preparation (“Worrying about a predicted negative event helps me to prepare for its occurrence”).

58
Q

The Negative Consequences of Worry

A
  • not enjoyable
  • people who worry about something tend subsequently to have more negative intrusive thoughts than people who do not worry
  • attempts to control thoughts and worry may paradoxically lead to increased experience of intrusive thoughts and enhanced perception of being unable to control them
  • perceptions of uncontrollability are also known to be associated with increased anxiety, so a vicious circle of anxiety, worry, and intrusive thoughts may develop
59
Q
  • Neurotransmitter and Neurohormonal Abnormalites
A

a functional deficiency in GABA
GABA, serotonin, and perhaps norepinephrine all play a role in anxiety, but the ways in which they interact remain largely unknown

The CRH hormone may play an important role in generalized anxiety through its effects on the bed nucleus of the stria terminalis (an extension of the amygdala), which is now believed to be an important brain area mediating generalized anxiety

60
Q

Genetic Factors of OCD

A

Evidence from twin studies reveals a moderately high concordance rate for monozygotic twins and a lower rate for dizygotic twins.

Moderate genetic heritability, although it may be at least partially a nonspecific “neurotic” predisposition

Preliminary findings suggest that different genetic polymorphisms are implicated in OCD with Tourette’s syndrome and in OCD without Tourette’s syndrome, suggesting that these two forms of OCD are at least partially distinguishable at a genetic level

61
Q

OCD and the Brain

A
  • Basal Ganglia abnormalities
  • Abnormally high levels of activity in the subcortical caudate nucleus
  • The orbital frontal cortex seems to be where primitive urges regarding sex, aggression, hygiene, and danger come from
  • the overactivation of the orbital frontal cortex, which stimulates “the stuff of obsessions,” combined with a dysfunctional interaction among the orbital frontal cortex, the corpus striatum or caudate nucleus, and the thalamus (which is downstream from the corpus striatum) may be the central component of the brain dysfunction in OCD.
62
Q

Baxter’s theory

A
  • cortico-basal-ganglionic-thalamic circuit is normally involved in the preparation of complex sets of interrelated behavioral responses used in specific situations such as those involved in territorial or social concerns.
  • According to Baxter’s theory, the dysfunctions in this circuit in turn prevent people with OCD from showing the normal inhibition of sensations, thoughts, and behaviors that would occur if the circuit were functioning properly. In this case, impulses toward aggression, sex, hygiene, and danger that most people keep under control with relative ease “leak through” as obsessions and distract people with OCD from ordinary goal-directed behavior.
  • Evidence suggests that at least part of the reason that this circuit does not function properly may be due to abnormalities in white matter in some of these brain areas; white matter is involved in connectivity between various brain structures
63
Q

Specific Phobias - Treatment

A

Exposure therapy

  • invivo or imaginary
  • flooding
64
Q
  • Social Phobias - Treatment
A

Cognitive Therapy
- cognitive restructuring to change distorted automatic thoughts
Behavior Therapy
- exposure to social situations that evoke fear
Medications
- antidepressants
- relapse rate with medication is higher than with therapy

65
Q

Panic Disorder with or without Agoraphobia - Treatment

A
Medications
- anxiolytics (antianxiety)
- antidepressants
Behavioral treatments
cognitive-behavioral treatments
66
Q
  • Generalized Anxiety Disorder - Treatments
A

Anxiolytic (antianxitey; benzodiazepines and non-benzodiazepines)
- commonly used and misused
Buspirone seems effective and nonaddictive (nonbenzodiazepine)
Cognitive-behavioral therapy has become increasingly effective

67
Q

Body Dysmorphic Disorder - Treatments

A

• Antidepressants
• Cognitive-behavioral therapy
- Therapy emphasizing exposure and response prevention appears to be effective