Anxiety Flashcards

1
Q

What is anxiety

A

Recurrent emotional and physiological arousal in response to excessive perceptions of threat or danger

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2
Q

Common anxiety disorders of childhood

A

Generalised anxiety disorder

Social anxiety

Agoraphobia

Panic disorder

Separation anxiety disorder

Selective mutism

Specific phobia

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3
Q

Link between social, separation and generalised anxiety

A

Highly comorbid->60% chance of having more than one

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4
Q

When does normative separation anxiety peak and diminish

A

Peaks at 9-18 months and diminished at 2.5 years

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5
Q

Describe behaviourally inhibited children

A

Higher risk develop separation, social, GAD

Higher resting HR, +morning cortisol, low HR variability

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6
Q

Criteria Separation anxiety disorder

A

A. Developmentally inappropriate and excessive fear or anxiety concerning separation from those to whom the individual is attached, as evidenced by at least three of the following:

  1. Recurrent excessive distress when anticipating or experiencing separation from home or from major attachment figures.
  2. Persistent and excessive worry about losing major attachment figures or about possible harm to them, such as illness, injury, disasters, or death.
  3. Persistent and excessive worry about experiencing an untoward event (eg, getting lost, being kidnapped, having an accident, becoming ill) that causes separation from a major attachment figure.
  4. Persistent reluctance or refusal to go out, away from home, to school, to work, or elsewhere because of fear of separation.
  5. Persistent and excessive fear of or reluctance about being alone or without major attachment figures at home or in other settings.
  6. Persistent reluctance or refusal to sleep away from home or to go to sleep without being near a major attachment figure.
  7. Repeated nightmares involving the theme of separation.
  8. Repeated complaints of physical symptoms (eg, headaches, stomachaches, nausea, vomiting) when separation from major attachment figures occurs or is anticipated.

B. The fear, anxiety, or avoidance is persistent, lasting at least four weeks in children and adolescents and typically six months or more in adults.

C. The disturbance causes clinically significant distress or impairment in social, academic, occupational, or other important areas of functioning.

D. The disturbance is not better explained by another mental disorder, such as refusing to leave home because of excessive resistance to change in autism spectrum disorder; delusions or hallucinations concerning separation in psychotic disorders; refusal to go outside without a trusted companion in agoraphobia; worries about ill health or other harm befalling significant others in generalized anxiety disorder; or concerns about having an illness in illness anxiety disorder.

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7
Q

Criteria Generalised anxiety disorder

A

A. Excessive anxiety and worry (apprehensive expectation), occurring more days than not for at least six months, about a number of events or activities (such as work or school performance).

B. The individual finds it difficult to control the worry.

C. The anxiety and worry are associated with three (or more) of the following six symptoms (with at least some symptoms having been present for more days than not for the past six months):

Note: Only one item is required in children:

  1. Restlessness or feeling keyed up or on edge
  2. Being easily fatigued
  3. Difficulty concentrating or mind going blank
  4. Irritability
  5. Muscle tension
  6. Sleep disturbance (difficulty falling or staying asleep, or restless, unsatisfying sleep)

D. The anxiety, worry, or physical symptoms cause clinically significant distress or impairment in social, occupational, or other important areas of functioning.

E. The disturbance is not attributable to the physiological effects of a substance (eg, a drug of abuse, a medication) or another medical condition (eg, hyperthyroidism).

F. The disturbance is not better explained by another mental disorder (eg, anxiety or worry about having panic attacks in panic disorder, negative evaluation in social anxiety disorder (social phobia), contamination or other obsessions in obsessive-compulsive disorder, separation from attachment figures in separation anxiety disorder, reminders of traumatic events in posttraumatic stress disorder, gaining weight in anorexia nervosa, physical complaints in somatic symptom disorder, perceived appearance flaws in body dysmorphic disorder, having a serious illness in illness anxiety disorder, or the content of delusional beliefs in schizophrenia or delusional disorder).

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8
Q

Criteria Social Anxiety disorder

A

A. Marked fear or anxiety about one or more social situations in which the individual is exposed to possible scrutiny by others. Examples include social interactions (eg, having a conversation, meeting unfamiliar people), being observed (eg, eating or drinking), and performing in front of others (eg, giving a speech).

Note: In children, the anxiety must occur in peer settings and not just during interaction with adults.

B. The individual fears that he or she will act in a way or show anxiety symptoms that will be negatively evaluated (ie, will be humiliating or embarrassing; will lead to rejection or offend others).

C. The social situations almost always provoke fear or anxiety.

Note: In children, the fear or anxiety may be expressed by crying, tantrums, freezing, clinging, shrinking, or failing to speak in social situations.

D. The social situations are avoided or endured with intense fear or anxiety.

E. The fear or anxiety is out of proportion to the actual threat posed by the social situation and to the sociocultural context.

F. The fear, anxiety, or avoidance is persistent, typically lasting for six months or more.

G. The fear, anxiety, or avoidance causes clinically significant distress or impairment in social, occupational, or other important areas of functioning.

H. The fear, anxiety, or avoidance is not attributable to the physiological effects of a substance (eg, a drug of abuse, a medication) or another medical condition.

I. The fear, anxiety, or avoidance is not better explained by the symptoms of another mental disorder, such as panic disorder, body dysmorphic disorder, or autism spectrum disorder.

J. If another medical condition (eg, Parkinson’s disease, obesity, disfigurement from burns or injury) is present, the fear, anxiety, or avoidance is clearly unrelated or is excessive.

Specify if performance only — If the fear is restricted to speaking or performing in public.

The diagnosis of social anxiety disorder requires that a child has age appropriate relationships with the people familiar to him, and anxiety around less familiar peers and adults

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9
Q

Lifetime prevalence of any anxiety disorder in children

A

10-27%, most common GAD

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10
Q

Biopsychosocial factors in separation/social/general

A

Parental overprotection

Insecure parent-child attachment

Maternal depression/anxiety

Temperamental: shyness, withdrawl in unfamiliar situations

Death, illness, change environment

+activation amygdala in stress, hyperactivation

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11
Q

Social learning factors

A

Parent modelling of anxiety->phobic adaptation

Overprotection-> interpersonal sensitivity

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12
Q

Genetic factors

A

Accounts for 1/3 variance

36-65% heritability

Behavioural inhibition and physiological hyperarousal

Emotional reactivity

Increased negative affect

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13
Q

Differential diagnosis

A

GAD

Soc AD

MDD

Panic disorder w/ agorophobia

PTSD

ODD

Dysthymic

Selective mutism

ADHD

OCD

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14
Q

Predictors of future rmission

A

Younger age at initiation of treatment

Lower severity

Absence of comorbid depressive/anxiety

Absence of primary anxiety disorder being social anxiety

Most recover in first year

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15
Q

Predictors of slower recovery

A

Early age onset, later treatment

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16
Q

Treatment of spearation/soc/GAD

A

CBT

Family education

Family psychosocial intervention

SSRIs->fluvoxamine, fluoxetine, sertraline, paroxetine

Best EBM= CBT (exposure)+ SSRI->if able to manage daily activities, start with CBT. If severe combination.

Coping Cat, CALM program

17
Q

Before presrcibing for anxiety disorders

A

Exclude other diagnoses->

  1. Psychiatric: depression (inattention, sleep), bipolar (irritability, sleep, restless), ODD (irritability, oppositional), psychotic (withdrawal, restless), ADHD (inattention restless) , learning disability
  2. Medical:
    a) hyperthyroid, hypoglycemia, phaeochromocytoma
    b) Migraine, seizures, delirium, tumor
    c) arrythmias, asthma, lead
    d) asthma med, sympathomimetics, sterois, SSRI, antipsychotics, diet, cold, caffeine, energy drinks

Beware contraindications/interactions

Measure baseline severity: ADIS, Kiddie-Schedule for Affective disorders and SchizoP, RCADS. SCARED, MASC, CGI

Obtain consent

18
Q

Prescribing for anxiety

A

81% response with CBT and sertraline

Blackbox warning->for depressive, not based on anxiety

Venlafaxine second line

Benzo use not supported by controlled trials->however may be considered to potentiate initial titration with SSRIs and for rapid tranquilisation

19
Q

After prescribing

A

Acute: start low, titrate. Monitor response. SE->GIT, HA motor, insomnia

Effect should be 3-6 weeks, max at 12-16

If partial/no-> diagnosis, adequacy, compliance

Consider adding CBT, changing med, combingin

Maintenence: continue for 1 year of stable improvement

Discontinuation: trial off med started at low demand time

Taper slowly

Monitor for recurrene

20
Q

Externalising disorders of childhood

A

ADHD, ODD, Conduct disorder

21
Q

When does SAD normally present

A

Generally prepubertal condition presenting 7.5 years.

More in females, although no difference in symptom presentation

22
Q

Is SAD more common in upper/middle or lower SES

A

Lower-> perhaps owing to hidden biological propensity more likely expressed owing to cumulative stress burden, higher in children from impoverished settings

23
Q

Etiology of SAD

A

Inadequately reslved separation/individuation conflict

Vulnerability determined by temperament

Security of attachment

Behavioural contingencies

Decisive empirical data lacking

24
Q

Possible precipitants for acute onset SAD

A

Move, change of school, loss of a loved one, illness, prolonged absence from school

Waxes and wanes

25
Q

Greater risk of chronicity for SAD

A

Later age onset

Comorbidities

Familial pathology

Missing >1 year school

26
Q

Most common co-morbidities for SAD

A

GAD and speciic phobias

Depression->typically preceeds

+panic disorder= ++functional impairment

27
Q

Important history in SAD

A

Preceeding events

Response to parens departure

Ensuing behaviour

Consequences of separation

Symptoms: thoughts/worries/nightmares about separation

28
Q

Anxiety rating scales

A

Screen for child anxiety related emotional disorders

Multidimensional Anxiety Scale for Children

29
Q

Normal developmental fears

A
30
Q

Differential diagnosis for SAD

A

(school refusal eg)

ODD, CD

Other anxiety disorders

Mood disorders

Psychotic disorders, PTSD, Panic,

Pervasive development disorder, learning disorders

31
Q

Peak age for school refusal

A

5-6, 10-11 and 13-15

Transitory periods

32
Q

DDx for school refusal

A

SAD

GAD

Specific phobia

Social phobia

Panic disorder

PTSD

OCD

Conduct/ODD->truancy

33
Q

‘Treatment’ for school refusal

A

<2 weeks->inform parnts of disorder, get cooperation, encourage.

SHow emapathy/understanding, insit in firm way for regular school attendance

Provide skills to master fears

Parent may attend class initially eg

Reward ‘brave’ behaviour

>2 weeks->CBT, School refusal assessment scale to identify the negative.positive reinforces

34
Q
A