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Drug Mech Test 3 > Antivirals > Flashcards

Antivirals Flashcards

1
Q

Which drug is used for HSV and VZV?

A

Acyclovir

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2
Q

Which drugs are an acyclic guanine derivative?

A

Acyclovir

Ganiciclovir

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3
Q

What are the antivirals for CMV?

A

Ganciclovir
Cidofovir
Foscarnet

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4
Q

Which drug is a cytosine nucleotide analog?

A

Cidofovir

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5
Q

Which drug is an inorganic pyrophosphate analog?

A

Foscarnet

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6
Q

Which drug is 100 times more effective than Acyclovir for CMV?

A

Ganiciclovir

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7
Q

Which drug is only anti-HSV for IV use?

A

Acyclovir

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8
Q

Which drug is selectively activated and accumulates only in the infected cells?

A

Acyclovir

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9
Q

Which drug requires no phosphorylation and will not compete with the nucleosides?

A

Foscarnet

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10
Q

Which drug is a nucleotide so it only requires 2 phosphorylation steps and is independent of viral enzymes?

A

Cidofovir

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11
Q

Which class is Zidovudine (Azidothrymidine-AZT) in?

A

Nucleoside-RTIs

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12
Q

Which class is Tenofovir in?

A

Nucleotide-TRIs

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13
Q

Which class is Nevirapine in?

A

NNRTIs

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14
Q

Which class is Ritonavir and Saquinavir in?

A

Protease inhibitor

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15
Q

Which class is Enfuviritide in?

A

Fusion Inhibitor

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16
Q

Which class is Maraviroc in?

A

CCR5 Antagonists

17
Q

Which class is Raltegravir-Isentress in?

A

InSTIs

18
Q

Which drug is a nucleotide analog of adenosine monophosphate?

A

Adefovir

19
Q

Which drug is a cytokine (endogenous proteins)?

A

Interferon Alfa

20
Q

Which drug is a guanosine analog?

A

Ribavirin

21
Q

Which drug is a third oral protease inhibitor?

A

Simeprevir

22
Q

Which drug is a uridine nucleotide analog?

A

Sofosbuvir

23
Q

Which drug is used to treat for HBV only?

A

Adefovir

24
Q

Which drug is used to treat for both HBV and HCV?

A

Interferon Alfa

25
Q

Which drug is used to treat for HCV only?

A

Ribavirin

26
Q

Which drugs are used to treat chronic HCV?

A

Simeprevir

Sofosbuvir

27
Q

Which drug is used in combination with Interferon Alfa?

A

Ribavirin

28
Q

Which drug is administered SQ or IM?

A

Interferon Alfa

29
Q

Which anti-Hep drug is generally well tolerated?

A

Sofosbuvir

30
Q

Which drugs are neuraminidase inhibitors?

A

Zanamivir

Oseltamivir

31
Q

What are the drugs used for anti-influenza therapy?

A

Zanamivir

Oseltamivir

32
Q

Which drugs are active against both influenza A and B?

A

Zanamivir

Oseltamivir

33
Q

Which anti-influenza drug is give through oral inhalation?

A

Zanamivir

Drug Mech Test 3 (3 decks)

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