Antivirals Flashcards
1
Q
What are Viruses made up of?
A
viruses are obligate intracellular parasites, rely on biosynthetic machinery to reproduce
-when not inside an infected cell, viruses exist as independent particles (virions) `
2
Q
What do Virions consist of?
A
- double or single stranded DNA or RNA
-a protein coat (capsid)
-some also possess a lipid envelope derived from the host cell which may contain antigenic glycoprotein
3
Q
shape of capsid
A
a way to classify viruses based on their shape
- helical, isosahedral, complex
4
Q
pathogenecity
A
ability of viruses to cause disease
- degree of pathogenecity is called virulence
5
Q
Life Cycle of Viral replication
A
absorption, penetration, replication, release
6
Q
Central Dogma of Biology
A
- eukaryotes and prokaryotes make protein from an mRNA template
DNA - mRNA - protein (one direction) - DNA can either be transcribed or replicated
-DNA replication and transcription happen in the nucleus
7
Q
DNA Viruses
A
- most DNA viruses enter the host cell nucleus, where the viral DNA is often integrated into the host genome and transcribed into mRNA by host DNA -dependent RNA polymerase; mRNA is tranlate
