ANTIVIRAL IMMUNITY & VIRUS VACCINES

Question 1

2 types of immunity:

Answer 1

INNATE IMMUNITY

ADAPTIVE IMMUNITY

Question 2

Production of cytokines (small proteins affecting the behavior of other cells)

Answer 2

INTERLEUKINS - cytokines made by lymphocytes.

INTERFERONS - key family of cytokines

Question 3

Key elements of antiviral resistance at the cellular level

Answer 3

INTERFERONS

Question 4

Activated via cellular receptors

Answer 4

PATTERN RECOGNITION RECEPTORS (PRRs)

Question 5

Class of Pattern Recognition Receptors (PRR):

Answer 5

TLR7 & TLR8 (Toll-Like Receptors) - Bind ssRNA, detect RNA virus infections

TLR3 (Toll-Like Receptors) - detects dsRNA